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Britannilactone diacetate

Catalog No. TN2511 CAS 1286694-67-4

Synonyms: 1,6-O,O-Diacetylbritannilactone

1,6-O,O-Diacetylbritannilactone(OODBL) has anti-inflammatory activity, it has a potential therapeutic efficacy on inflammatory diseases especially allergic airway disease as a lead compound. OODBL has anti-asthmatic activity, it reduces leukotriene C4 production and degranulation through the suppression of cytosolic phospholipase A2 phosphorylation and phospholipase Cγ-mediated Ca2+ influx in IgE/antigen-stimulated BMMCs. OODBL also exhibits potent antitumor activity against several human cancer cell lines.

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Britannilactone diacetate, CAS 1286694-67-4

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	1,6-O,O-Diacetylbritannilactone
Molecular Weight	350.41
Formula	C19H26O6
CAS No.	1286694-67-4

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Britannilactone diacetate 1286694-67-4 DNA损伤和修复 JAK/STAT信号通路 MAPK信号通路表观遗传蛋白酶体凋亡干细胞免疫与炎症血管生成 Caspase MAPK JNK JAK IL Receptor PARP STAT ROS 1,6-O,O-Diacetylbritannilactone Inhibitor inhibitor inhibit

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