Powder: -20°C for 3 years
In solvent: -80°C for 2 years
1,6-O,O-Diacetylbritannilactone(OODBL) has anti-inflammatory activity, it has a potential therapeutic efficacy on inflammatory diseases especially allergic airway disease as a lead compound. OODBL has anti-asthmatic activity, it reduces leukotriene C4 production and degranulation through the suppression of cytosolic phospholipase A2 phosphorylation and phospholipase Cγ-mediated Ca2+ influx in IgE/antigen-stimulated BMMCs. OODBL also exhibits potent antitumor activity against several human cancer cell lines.
Description | 1,6-O,O-Diacetylbritannilactone(OODBL) has anti-inflammatory activity, it has a potential therapeutic efficacy on inflammatory diseases especially allergic airway disease as a lead compound. OODBL has anti-asthmatic activity, it reduces leukotriene C4 production and degranulation through the suppression of cytosolic phospholipase A2 phosphorylation and phospholipase Cγ-mediated Ca2+ influx in IgE/antigen-stimulated BMMCs. OODBL also exhibits potent antitumor activity against several human cancer cell lines. |
Synonyms | 1,6-O,O-Diacetylbritannilactone |
Molecular Weight | 350.41 |
Formula | C19H26O6 |
CAS No. | 1286694-67-4 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
( < 1 mg/ml refers to the product slightly soluble or insoluble )
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Britannilactone diacetate 1286694-67-4 DNA损伤和修复 JAK/STAT信号通路 MAPK信号通路 表观遗传 蛋白酶体 凋亡 干细胞 免疫与炎症 血管生成 Caspase MAPK JNK JAK IL Receptor PARP STAT ROS 1,6-O,O-Diacetylbritannilactone Inhibitor inhibitor inhibit