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Aminoadipic acid

Catalog No. T4705 CAS 542-32-5

Synonyms: DL-2-Aminoadipic acid

Aminoadipic acid (DL-2-Aminoadipic acid) (2-aminoadipate) is a metabolite in the principal biochemical pathway of lysine. It is an intermediate in the metabolism (i.e. breakdown or degradation) of lysine and saccharopine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor N-methyl-D-aspartate (NMDA). Aminoadipic acid has also been shown to inhibit the production of kynurenic acid, a broad spectrum excitatory amino acid receptor antagonist, in brain tissue slices.

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Aminoadipic acid, CAS 542-32-5

Pack Size	Availability	Price/USD
500 mg	In stock	$ 42.00
1 g	In stock	$ 74.00
1 mL * 10 mM (in H2O)	In stock	$ 46.00

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Purity: 99.7%

Purity: 98.1%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	DL-2-Aminoadipic acid
Molecular Weight	161.16
Formula	C6H11NO4
CAS No.	542-32-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: Insoluble

H2O: 10 mM

References and Literature

1. Wang TJ, et al. 2-Aminoadipic acid is a biomarker for diabetes risk. J Clin Invest. 2013 Oct;123(10):4309-17. 2. Wang X, et al. α-Aminoadipic acid protects against retinal disruption through attenuating Müller cell gliosis in a rat model of acute ocular hypertension. Drug Des Devel Ther. 2016 Oct 20;10:3449-3457.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Human Endogenous Metabolite Library RO5 Drug-like Natural Product Library Bioactive Compound Library Natural Product Library for HTS NO PAINS Compound Library Natural Product Library Bioactive Compounds Library Max Human Endogenous Metabolite Compound Library Plus Gut Microbial Metabolite Library

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Keywords

Aminoadipic acid 542-32-5 Metabolism Others Endogenous Metabolite inhibit Inhibitor DL-2-Aminoadipic acid inhibitor

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