store at low temperature,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
4-Vinylphenol is the metabolite of p-coumaric and ferulic acid by lactic acid bacteria in wine found in Hedyotis diffusa Willd. 4-Vinylphenol induces apoptosis in vivo.
Pack Size | Availability | Price/USD | Quantity |
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100 mg | In stock | $ 50.00 |
Description | 4-Vinylphenol is the metabolite of p-coumaric and ferulic acid by lactic acid bacteria in wine found in Hedyotis diffusa Willd. 4-Vinylphenol induces apoptosis in vivo. |
In vitro | 4-Vinylphenol (100 µg/mL) notably enhances caspase 3 expression, effectively making CSC-enriched MDAMB-231 cells more prone to apoptosis. At concentrations of 50 and 100 µg/mL, it dramatically inhibits cell proliferation in these cells. Furthermore, 4-Vinylphenol at a range of 12.5-200 µg/mL substantially decreases cell viability in parental MDA-MB-231 cells, with an IC50 value determined at 109 µg/mL. At lower doses (0.15, 0.3 µg/mL), it diminishes sphere formation and vimentin expression in CSCs, indicative of its potential in targeting breast cancer. Notably, 4-Vinylphenol cuts down ALDH1A1 expression by half in CSC-enriched MDA-MB-231 cells[1]. |
Source |
Molecular Weight | 120.15 |
Formula | C8H8O |
CAS No. | 2628-17-3 |
store at low temperature,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 145 mg/mL (1206.82 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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4-Vinylphenol 2628-17-3 Apoptosis Metabolism Endogenous Metabolite tumor blood Inhibitor invasive 4 Vinylphenol formation vessels 4Vinylphenol inhibit breast inhibitor