Shopping Cart

Your shopping cart is currently empty

(+)-PD 128907 hydrochloride

Name: (+)-PD 128907 hydrochloride
Brand: TargetMol
SKU: T7553
Price: 37 USD
Availability: InStock
Rating: 5 (10 reviews)

Copy Product Info

😃Good

Catalog No. T7553Cas No. 300576-59-4

(+)-PD 128907 hydrochloride is an agonist of the D3 dopamine receptor.

(+)-PD 128907 hydrochloride

Copy Product Info

😃Good

Purity: 97.76%

Catalog No. T7553Cas No. 300576-59-4

(+)-PD 128907 hydrochloride is an agonist of the D3 dopamine receptor.

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$37	In Stock	In Stock
10 mg	$58	In Stock	In Stock
25 mg	$117	In Stock	In Stock
50 mg	$207	In Stock	In Stock
100 mg	$302	In Stock	In Stock
200 mg	$428	-	In Stock
1 mL x 10 mM (in DMSO)	$56	In Stock	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:97.76%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

(+)-PD 128907 hydrochloride AI Summary

(+)-PD 128907 hydrochloride exhibits a diverse range of bioactivities, including modulation of Lamin A splicing, inhibition of APE1 endonuclease, modulation of lipid storage in Drosophila S3 cells, inhibition of Bloom's syndrome helicase, antagonism of the Neuropeptide S receptor, inhibition of histone lysine methyltransferase G9a, interference with Rango - Importin beta complex formation, inhibition of malarial parasite plastid function, inhibition of HP1-beta chromodomain interactions, inhibition of mammalian selenoprotein thioredoxin reductase 1, blocking Marburg Virus binding or entry into cells, inhibition of Glutaminase, inhibition of Hepatitis C Virus, modulation of the 5-hydroxytryptamine receptor 2A, inhibition of ERG Ets/DNA interaction, and activation of D3 Dopamine Receptor B-arrestin..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	(+)-PD 128907 hydrochloride is an agonist of the D3 dopamine receptor.
Targets&IC50	D3 receptor (human):1.7 nM (Ki), D3 receptor (rat):0.84 nM (Ki), D2 receptor (rat):770 nM (Ki), D2 receptor (human):179 nM (Ki)

Chemical Properties

Molecular Weight	285.77
Formula	C₁₄H₂₀ClNO₃
Cas No.	300576-59-4
Smiles	CCCN1CCO[C@@H]2c3cc(O)ccc3OC[C@H]21.Cl
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 150 mg/mL (524.9 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (14 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.4993 mL	17.4966 mL	34.9932 mL	174.9659 mL
5 mM	0.6999 mL	3.4993 mL	6.9986 mL	34.9932 mL
10 mM	0.3499 mL	1.7497 mL	3.4993 mL	17.4966 mL
20 mM	0.1750 mL	0.8748 mL	1.7497 mL	8.7483 mL
50 mM	0.0700 mL	0.3499 mL	0.6999 mL	3.4993 mL
100 mM	0.0350 mL	0.1750 mL	0.3499 mL	1.7497 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc