ulcerogenic — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T40377	Nicotredole	Tryptamide	Others
	Nicotredole (Tryptamide) (Tryptamide) is an orally active analgesic and anti-inflammatory agent. Nicotredole exhibits evident anti-inflammatory effects of potency comparable with Phenylbutazone. Nicotredole has only weak...		Others
T4503	Talniflumate	Somalgen	Chloride channel , COX , N-Acetylglucosaminyltransferase , Anion Exchanger
	Talniflumate (Somalgen) is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell culture. It possesses anti-inflammatory actions via inhibition o...
T3S0509	Gaultherin		COX
	Gaultherin has analgesic, and anti-inflammatory activities.Gaultherin lacks gastric ulcerogenic effect, because of it released salicylate in intestine slowly, not in stomach and it left the cyclooxygenase-1 unaffected, w...		COX
T24090	Glaziovine
	Glaziovine is an agent of anti-ulcerogenic natural alkaloid.
TN5030	Sitoindoside I		Antifection
	Sitoindoside I has anti-ulcerogenic activity.		Antifection
TN1642	Ferruginol		BCL , PARP , Caspase
	Ferruginol has anti-plasmodial, leishmanicidal, anti-ulcerogenic, cardioprotective, anticancer, anti-oxidative and anti-inflammatory activities, it can induce apoptosis in non-small cell lung cancer (NSCLC) cells.		BCL , PARP , Caspase
T64063	COX-2-IN-24
	COX-2-IN-24 is an orally active COX-2 inhibitor (IC50: 0.17 μM) with anti-inflammatory and hypo-ulcerogenic effects.
T63348	COX-2-IN-23
	COX-2-IN-23 is a selective inhibitor of COX-2, with IC50 values of 0.28 and 20.14 μM for COX-2 and COX-1, respectively.COX-2-IN-23 exhibits anti-inflammatory effects as well as low ulcerogenic effects.
T83599	(+)-Leucocyanidin	2,3-trans-3,4-trans-Leucocyanidin,(2R,3S,4R)-Leucocyanidin,3,4-trans-Leucocyanidin
	(+)-Leucocyanidin, an isoform of leucocyanidin and potent anti-ulcerogenic agent, has been extracted from Litchi chinensis. This compound exhibits considerable protective properties in rat models against aspirin-induced ...
T60978	COX-2-IN-7
	COX-2-IN-7 (compound 4a) is a potent, selective, and orally active COX-2 inhibitor which is higher selectivity than Celecoxib with an IC 50 value of 6.585 uM. COX-2-IN-7 has good anti-inflammatory and low ulcerogenic act...
T63104	INOS/PGE2-IN-1
	iNOS/PGE2-IN-1 is an iNOS/PGE2 inhibitor and a potent anti-inflammatory agent. iNOS/PGE2-IN-1 exhibits an inhibitory effect on LPS-induced NO production and has a low ulcerogenic potential.
T27968	M-5011	T-3788,S-MTPPA,M 5011,M-5011C
	M-5011 is a non-steroidal anti-inflammatory drug and immunomodulator potentially for the treatment of inflammation and pain. M-5011 had an effective antinociceptive activity (ED50 value) of 0.63 mg/kg. M-5011 partially i...
T63646	COX-2-IN-9
	COX-2-IN-9 is a selective, potent, orally active COX-2 inhibitor (IC50: 10.17 μM).COX-2-IN-9 has a higher COX-2 selectivity than Celecoxib.COX-2-IN-9 exhibits good in vivo anti-inflammatory activity and low ulcerogenic e...
T78705	COX-2-IN-30		COX
	COX-2-IN-30, a benzenesulfonamide derivative, is an orally active, dual inhibitor of cyclooxygenase-2 (COX-2; IC50 = 49 nM) and cyclooxygenase-1 (COX-1; IC50 = 10.4 μM), as well as 5-lipoxygenase (5-LOX; IC50 = 2.4 μM). ...		COX