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Search Results for " thrombopoietin "

Targets

14

Compounds

10

Recombinant Proteins

Cat No. Product Name Synonyms Targets
TQ0223 Lusutrombopag S-888711,Mulpleta Thrombin , Thrombopoietin Receptor
Lusutrombopag (Mulpleta) is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist for chronic liver disease (CLD) patients with thrombocytopenia prior to elective invasive surgery.
T2562 Eltrombopag SB-497115,SB-497115-GR Thrombin
Eltrombopag (SB-497115-GR), an orally active thrombopoietin receptor agonist with megakaryopoiesis stimulating activity, binds to and stimulates the platelet thrombopoietin receptor (TPO-R or CD110).
T6825 Eltrombopag Olamine Promacta Olamine,Revolade,Eltrombopag diethanolamine salt,SB497115,SB-497115GR Thrombin
Eltrombopag Olamine (Eltrombopag diethanolamine salt) is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrom...
T7417 Avatrombopag YM477,AKR-501,E5501 Thrombin , Thrombopoietin Receptor
Avatrombopag (YM477) is a new oral thrombopoietin (TPO) receptor agonist, activating TPO receptor and increasing megakaryocytic proliferation/differentiation and platelet production.
T67894 Butyzamide Thrombopoietin Receptor , JAK
Butyzamide is an effective and oral Mpl activator. It is a novel non-peptide-based molecule with antagonistic effects on thrombopoietin (TPO) receptors, which promotes proliferation of human Mpl (hMpl) expression and mou...
T27536 Hetrombopag olamine
Hetrombopag olamine is a non-peptide thrombopoietin (TPO) receptor agonist with oral activity.
T17146 TPO agonist 1 Others
TPO agonist 1 is a thrombopoietin agonist. It would be useful as promoters of thrombopoiesis and megakaryocytopoiesis to treat thrombocytopenia.
T62865 Rafutrombopag
Rafutrombopag is a thrombopoietin (TPO) agonist.
T38602 (E/Z)-Eltrombopag 13C4 (E/Z)-Eltrombopag 13C4,(E/Z)-SB-497115 13C4
(E/Z)-Eltrombopag 13C4 ((E/Z)-SB-497115 13C4) is a mixture complex of E-Eltrombopag and Z-Eltrombopag, with 13C labeled. Z-Eltrombopag is a thrombopoietin (TPO) receptor agonist developed for certain conditions that lead...
T62864 Hetrombopag
Hetrombopag is a potent agonist of the thrombopoietin receptor. Hetrombopag is well tolerated and has a controlled safety profile. hetrombopag has potential for studies in immune thrombocytopenia.
T68560 Totrombopag choline
Totrombopag, also known LGD-4665, GSK2285921 and SB559448, is an oral thromobopoietin receptor agonist, is being developed as a new generation small molecule thrombopoietin (TPO) mimetic. It is a highly selective and po...
T40654 Avatrombopag hydrochloride AKR-501 hydrochloride,YM477hydrochloride,E5501hydrochloride
Avatrombopag hydrochloride (AKR-501) is an orally active, nonpeptide agonist of the thrombopoietin (TPO) receptor with an EC 50 of 3.3 nM. It effectively mimics the biological activities of TPO, stimulating platelet prod...
T72265 Eltrombopag methyl ester
Eltrombopag Methyl Ester, a derivative of Eltrombopag, functions as a thrombopoietin (Tpo) receptor agonist to enhance platelet production and is employed in the study of certain thrombocytopenia variants.
T68888 Avatrombopag maleate
Avatrombopag, also known as AKR-501, YM477, AS 1670542 or E5501, is a novel orally-active thrombopoietin (TPO) receptor agonist. AKR-501 specifically targeted the TPO receptor and stimulated megakaryocytopoiesis througho...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-00939 Thrombopoietin Protein, Mouse, Recombinant (His) Mouse HEK293
Thrombopoietin (TPO or THPO), also known as myeloproliferative leukemia virus ligand (c-Mpl), is a hematopoietic growth factor belonging to the EPO/TPO family. The thrombopoietin protein is produced mainly by the liver a...
TMPY-01609 Thrombopoietin Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Thrombopoietin (TPO or THPO), also known as myeloproliferative leukemia virus ligand (c-Mpl), is a hematopoietic growth factor belonging to the EPO/TPO family. The thrombopoietin protein is produced mainly by the liver a...
TMPY-04201 Thrombopoietin Protein, Human, Recombinant (hFc) Human HEK293
Thrombopoietin (TPO or THPO), also known as myeloproliferative leukemia virus ligand (c-Mpl), is a hematopoietic growth factor belonging to the EPO/TPO family. The thrombopoietin protein is produced mainly by the liver a...
TMPY-05423 C-MPL Protein, Rat, Recombinant (hFc) Rat HEK293
CD11, also known as c-MPL, is a 635 amino acid transmembrane domain, with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs. It is expressed at a low level in a large number o...
TMPJ-00235 TPO Protein, Human, Recombinant (His) Human Human Cells
Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. It produced by the liver and kidney which regulates the production of platelets. TPO stimulates the production and differentiation of me...
TMPY-03421 C-MPL Protein, Rat, Recombinant (His) Rat Baculovirus-Insect Cells
CD11, also known as c-MPL, is a 635 amino acid transmembrane domain, with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs. It is expressed at a low level in a large number o...
TMPY-06797 C-MPL Protein, Human, Recombinant (His) Human HEK293
CD11, also known as c-MPL, is a 635 amino acid transmembrane domain, with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs. It is expressed at a low level in a large number o...
TMPY-06863 C-MPL Protein, Mouse, Recombinant (His) Mouse HEK293
CD11, also known as c-MPL, is a 635 amino acid transmembrane domain, with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs. It is expressed at a low level in a large number o...
TMPK-00874 Thyroid Peroxidase Protein, Mouse, Recombinant (His) Mouse HEK293
Thyroid peroxidase, also called thyroperoxidase (TPO) or iodide peroxidase that encodes a 933 amino-acid residue (aa) molecule with a single membrane-spanning region. Thyroid peroxidase plays a key role in thyroid hormon...
TMPH-02274 JAK2 Protein, Human, Recombinant (His) Human E. coli
Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cyto...
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