splenic — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T5405	BI-1347		CDK
	BI-1347 is a potent, selective inhibitor of CDK8/cyclinC (IC50: 1 nM). It shows tumor growth inhibition in an in vivo xenograft model.		CDK
T26745	BAY 73-1449	BAY-73-1449,BAY73-1449	Others
	BAY-73-1449 is an antagonist of prostacyclin receptor.		Others
T21459	Splenopentin diacetate	Thymopoietin III pentapeptide (32-36),SP5,Splenopentin Acetate,Splenin pentapeptide (32-36),Arg-lys-glu-val-tyr	Others
	Splenopentin diacetate (Splenin pentapeptide (32-36)) is a synthetic immunomodulating peptide and can reproduce the biological activities of splenin and thymic hormone thymopoietin.		Others
T32088	Sovleplenib	HMPL 523,HMPL523,HMPL-523	Syk
	Sovleplenib (HMPL523) is an orally available, selective and potent inhibitor of the splenic tyrosine kinase SYK with an IC50 of 25 nM.Sovleplenib has antitumor activity and may be used in studies of immune thrombocytopen...		Syk
T11449L	Golotimod	Gamma-D-glutamyl-L-tryptophan,SCV 07	Antibiotic
	Golotimod (SCV 07) is an antimicrobial dipeptide with immunomodulatory activity that significantly improves the efficacy of anti-tuberculosis therapy, induces thymic and splenic cell proliferation, modulates macrophage f...		Antibiotic
T36696	DMBA
	7,12-Dimethylbenz[a]anthracene (DMBA) is a polycyclic aromatic hydrocarbon (PAH) that has been found in tobacco smoke and diesel exhaust and has carcinogenic activity.1,2It undergoes metabolic activation by numerous enzy...
T3289L	Amifostine Hydrate
	Amifostine Hydrate is a radiation protective agent that induces splenic vasodilation and blocks autonomic ganglion.
T3289L2	Amifostine sodium	WR-2721 sodium,WR2721 sodium,WR 2721 sodium
	Amifostine sodium is a phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
T37288	Remisporine B
	Remisporine B is a polyketide and derivative of remisporine A that has been found inPenicilliumand has immunosuppressant activity.1,2It inhibits LPS- or concanavalin A-induced proliferation of isolated mouse splenic lymp...
T36355	Sydowinin B
	Sydowinin B is a xanthone polyketide that has been found inA. sydowiiand has immunosuppressant activity.1It inhibits LPS- or concanavalin A-induced proliferation of isolated mouse splenic lymphocytes (IC50s = 19.2 and 20...
TP1962	Pam2CSK4
	Toll-like receptor 2/6 (TLR2/6) agonist. Induces TNF-α production in human mononuclear cells. Also induces proliferation and activation of mouse splenic B cells.
T35513	13C15-Nivalenol	13C15-Nivalenol
	13C15-Nivalenol is intended for use as an internal standard for the quantification of nivalenol by GC- or LC-MS. Nivalenol is a trichothecene mycotoxin that has been found inFusarium.1It is lethal to mice (LD50= 6.9 mg/k...
T40132	Insulin β Chain Peptide (15-23)
	Insulin β Chain Peptide (15-23), also referred to as INS, is an insulin-derived peptide that is specifically recognized by islet-associated T cells. The tetramer of Insulin β Chain Peptide (15-23) effectively stained the...
T62860	YM-341619
	YM-341619 (AS1617612) is a potent, orally active STAT6 inhibitor (IC50: 0.70 nM). YM-341619 inhibits IL-4-induced Th2 differentiation in mouse splenic T cells with an IC50 value of 0.28 nM, but does not affect Th1 cell d...
T35995	Ferrichrome (iron-free)
	Ferrichrome (iron-free) is a hydroxamate siderophore produced by various fungi (including U. sphaerogena) that facilitates iron chelation and uptake by these organisms and is also used by bacteria as a heterologous sider...
T11449	Golotimod hydrochloride (229305-39-9 free base)	Golotimod hydrochloride,Gamma-D-glutamyl-L-tryptophan hydrochloride,SCV 07 hydrochloride	STAT
	Golotimod hydrochloride (SCV 07 hydrochloride) is an immunomodulating peptide with antimicrobial properties. It enhances antituberculosis therapy effectiveness, promotes thymic and splenic cell proliferation, and boosts ...		STAT
T35515	3-Acetyldeoxy Nivalenol-13C17	3-Acetyldeoxy Nivalenol-13C17
	3-Acetyldeoxy nivalenol-13C17is intended for use as an internal standard for the quantification of 3-acetyldeoxy nivalenol by GC- or LC-MS. 3-Acetyldeoxy nivalenol is a mycotoxin that has been found inF. graminearum.1In ...