Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BAY 73-1449 is a selective and potent antagonist of the prostacyclin receptor(IC50<0.1 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 115.00 | |
5 mg | In stock | $ 247.00 | |
10 mg | In stock | $ 413.00 | |
25 mg | In stock | $ 692.00 | |
50 mg | In stock | $ 985.00 | |
100 mg | In stock | $ 1,330.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 272.00 |
Description | BAY 73-1449 is a selective and potent antagonist of the prostacyclin receptor(IC50<0.1 nM). |
Targets&IC50 | Prostacyclin receptor:<0.1 nM |
In vivo | In male Wistar rats, BAY 73-1449 (0.1-1 mg/kg; i.v.) significantly reduced splenic shunt vessel outflow without affecting mesenteric inflow[1]. BAY 73-1449 (1-5 mg/kg; s.c.) has no effects on portal pressures and the degree of porto-systemic shunting in rats[1]. |
Synonyms | BAY-73-1449, BAY73-1449 |
Molecular Weight | 425.48 |
Formula | C26H23N3O3 |
CAS No. | 693790-96-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/ml (129.27 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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BAY 73-1449 693790-96-4 Others vessel portal pressure,mesenteric porto-systemic inhibit BAY 731449 blood BAY 73 1449 prostacyclin inflow splenic Inhibitor shunt BAY-73-1449 lower Prostaglandin Receptor BAY73-1449 outflow inhibitor