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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1092 | Zolmitriptan | 311C90,BW-311C90 | 5-HT Receptor |
Zolmitriptan (311C90) selectively binds to and activates serotonin (5-HT) 1B receptors expressed in intracranial arteries and 5-HT 1D receptors located on peripheral trigeminal sensory nerve terminals in the meninges and... | |||
T1509 | Cyclobenzaprine hydrochloride | Cyclobenzaprine HCl,MK130 hydrochloride | 5-HT Receptor |
Cyclobenzaprine hydrochloride (MK130 hydrochloride) , a centrally acting muscle relaxant with antidepressant activity, leads to a reduction in muscle spasms. | |||
T33846 | Oxyphenonium bromide | Spasmophen,Oxifenon,Oxyfenon,Atrenyl,Oxyphenon | Others |
Oxyphenonium bromide (Oxyfenon) shows anticholinergic activity and can be used for research on the treatment of gastric and duodenal ulcers and for the relief of visceral spasms. | |||
T21447 | Tolazoline | Priscol,Priscoline,Pridazole,Divascol,Vasimid,Benzalolin | Adrenergic Receptor |
Tolazoline (Benzalolin), a non-selective competitive α-adrenergic receptor antagonist, is used as a vasodilator to treat spasms of peripheral blood vessels. It has also been used successfully as an antidote to reverse th... | |||
T1065 | Baclofen | Lioresal | GABA Receptor |
Baclofen (Lioresal) is a synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing Baclofen acts as a gamma-aminobutyric acid (GABA) agonist sp... | |||
T1475 | Fesoterodine fumarate | Toviaz,SPM 907 | AChR |
Fesoterodine fumarate (Toviaz) is the fumarate salt form of fesoterodine, a competitive muscarinic receptor antagonist with muscle relaxant and urinary antispasmodic properties. Fesoterodine is rapidly hydrolyzed in vivo... | |||
T0786 | Clidinium bromide | Ro 2-3773 | AChR |
Clidinium bromide (Ro 2-3773) , a synthetic anticholinergic agent, has been shown in experimental and clinical researchers to have a pronounced antisecretory and antispasmodic effect on the gastrointestinal tract. It can... | |||
T34121 | Pramiverine | EMD 9806,HSP 2986,EMD9806,HSP2986,EMD-9806 | |
Pramiverine is a long-acting choline dissolving agent used for gastrointestinal spasms. | |||
T25654 | Leiopyrrole | Leioplegil,DV 714,Leiopyrrolum,DV714,DV-714 | |
Leiopyrrole is an anticholinergic compound that can be used to relieve spasms. | |||
T21376 | Chlorphenesin Carbamate | Kolpicortin-sine,Rinlaxer,Chlorphensin carbamate,Maolate,laChlorphenesin Carbamate | |
Chlorphenesin Carbamate is a centrally acting muscle relaxant used to treat muscle pain and spasms and also an antifungal agent. | |||
T33314 | Methantheline Bromide | Frenogastrico,Dixamone bromide,Banthine,Asabaine,Methanthelinium bromide | |
Methantheline Bromide is a synthetic spasmolytic used to relieve cramps or spasms of the stomach, bowel, and bladder. It is also useful for intestinal or gastric ulcers (peptic ulcer disease), intestinal problems, pancre... | |||
T70153 | Pipoxolan hydrochloride | ||
Pipoxolan (HCl) is an antispasmodic drug. In vivo, the drug inhibited the contractions of intestines caused by neostigmine, barium chloride or injection of acetylcholine. The drug possesses ganglioplegic action and inhib... | |||
T69661 | Pipoxolan (free base) | ||
Pipoxolan (free base) is an antispasmodic drug. In vivo, the drug inhibited the contractions of intestines caused by neostigmine, barium chloride or injection of acetylcholine. The drug possesses ganglioplegic action and... | |||
T61453 | Propantheline | ||
Propantheline is an orally active antagonist of muscarinic acetylcholine receptors (mAChRs), commonly employed to investigate smooth muscle dysfunction, hyperhidrosis, smooth muscle spasms or cramps in the stomach, intes... | |||
T29000 | Tralomethrin | EPA Pesticide Chemical Code 121501,SAGA,HAG-107,HAG 107,Scout | |
Tralomethrin is used as a pyrethroid insecticide. It modifies the gating kinetics of the sodium channels in neurons, increases the length of time the channel remains open after a stimulus, thereby depolarizing the neuron... | |||
T25325 | Dicyclonon | LAB 145-138H,BAS 145-138 | |
Dicyclonon is a muscarinic antagonist utilized as an antispasmodic and in urinary incontinence. It has little effect on glandular secretion or the cardiovascular system. It has some local anesthetic properties and is uti... | |||
T37950 | 2-(Isopentylamino)naphthalene-1,4-dione | ||
2-(Isopentylamino)naphthalene-1,4-dione is a vitamin K analog.1It inhibits spasms induced by pentylenetetrazole and tonic hindlimb extension induced by maximal electroshock (MES) in mice (ED50s = 349.2 and 108.1 mg/kg, r... |