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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T74869 | SiRNA Negative Control | ||
siRNA Negative Control, a 21-nucleotide siRNA, serves as a negative control. | |||
T19080 | DOPE | Others | |
DOPE (DOPE) is a neutral helper lipid for cationic liposomes.It is used in combination with cationic phospholipids to increase efficiency during DNA transfection studies as a non-viral method of gene delivery. | |||
T0717L | Enoxacin | NSC 629661,AT 2266,Pd107779,CI 919 | DNA/RNA Synthesis , Topoisomerase , Antibacterial , Antibiotic |
Enoxacin (NSC-629661) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid. | |||
T0717 | Enoxacin hydrate | CI-919 hydrate,Enoxacin Sesquihydrate,AT-2266 hydrate | DNA gyrase , DNA/RNA Synthesis , Topoisomerase , Antibacterial , Antibiotic |
Enoxacin hydrate (AT-2266 hydrate) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent. | |||
T15139 | DLin-KC2-DMA | Others | |
DLin-KC2-DMA is a cationic/ionizable lipid. Which is used for siRNA delivery. | |||
T5823 | D-Lin-MC3-DMA | Others | |
D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle. | |||
T31546 | DLinDAP | D-Lin-DAP,D-LinDAP | Others |
DLinDAP (D-LinDAP) is an ionizable cationic lipid used for SiRNA delivery. | |||
T13254L | UNC10217938A HCl | UNC10217938A HCl(1347749-97-6 Free base),UNC7938 HCl | Others |
UNC10217938A HCl (UNC7938 HCl) is a 3-deazapteridine analog. UNC10217938A HCl exhibits strong oligonucleotide enhancing effects. UNC10217938A HCl can modulate their intracellular trafficking and release from endosomes, l... | |||
T15140 | DLinDMA | Others | |
DLinDMA, as a benchmark, is a key stable nucleic acid lipid particleslipid component. | |||
T8902 | DOTMA | Trimethyl[2,3-(dioleyloxy)propyl]ammonium Chloride,N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium | Others |
DOTMA (N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium) is a tetra-methylated DOTA analogue. DOTMA is a cationic lipid and can be used as a non-viral vector for gene therapy. It has been used as a component in lipos... | |||
T9098 | DMG-PEG 2000 | DMG-PEG2000 | Others |
DMG-PEG 2000 (DMG-PEG2000) is a lipid excipient that has been used in combination with other lipids in the formation of lipid nanoparticles. Formulations containing DMG-PEG 2000 have been used in the development of lipid... | |||
T64293 | SLN124 | ||
SLN124 is a GalNac-siRNA that targets transmembrane serine protease 6 (Tmprss6) and consists of a trimeric GalNAc ligand bound to TMPRSS6-siRNA. SLN124 has the potential to be used as an siRNA agent to restore ferroregul... | |||
T74447 | 503O13 | ||
503O13 is a degradable ionizable lipid for siRNA delivery. | |||
T39122 | Inclisiran | ALN-PCSsc | |
Inclisiran (ALN-PCSsc) is a double-stranded small interfering RNA (siRNA) compound that effectively suppresses PCSK-9 transcription. It proves promising in the investigation of hyperlipidemia and cardiovascular disease (... | |||
T74423 | Xalnesiran sodium | ||
Xalnesiran (sodium) is siRNA for the treatment of chronic hepatitis B ( HBV ).. | |||
T82481 | Elebsiran sodium | VIR-2218 sodium | |
Elebsiran sodium is an siRNA targeting hepatitis B and D virus infections [1]. | |||
T37035 | HAPC-Chol | ||
HAPC-Chol is a cationic cholesterol. HAPC-Chol, as part of a lipoplex with DOPE , has been used for siRNA delivery and gene silencing in MCF-7 cells in a luciferase assay without affecting cell viability. It has also bee... | |||
T74431 | Cemdisiran | ||
Cemdisiran, a conjugated siRNA with N-acetylgalactosamine (GalNAc), targets the liver to inhibit the production of complement 5 (C5) protein, serving as a potential therapeutic agent for the study of complement-mediated ... | |||
T39304 | Vutrisiran | ALN-TTRsc02 | |
Vutrisiran (ALN-TTRsc02) is an investigational, liver-directed small interfering ribonucleic acid (siRNA) compound designed for research on transthyretin (TTR)-mediated amyloidosis. | |||
T40203 | AZD-CO-Ph-PEG4-Ph-CO-AZD | AZD-CO-Ph-PEG4-Ph-CO-AZD | |
AZD-CO-Ph-PEG4-Ph-CO-AZD is a bis-β-lactam linker, commonly employed in the synthesis of antibody-siRNA conjugates. |