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Search Results for " sirna "

20

Compounds

Cat No. Product Name Synonyms Targets
T74869 SiRNA Negative Control
siRNA Negative Control, a 21-nucleotide siRNA, serves as a negative control.
T19080 DOPE Others
DOPE (DOPE) is a neutral helper lipid for cationic liposomes.It is used in combination with cationic phospholipids to increase efficiency during DNA transfection studies as a non-viral method of gene delivery.
T0717L Enoxacin NSC 629661,AT 2266,Pd107779,CI 919 DNA/RNA Synthesis , Topoisomerase , Antibacterial , Antibiotic
Enoxacin (NSC-629661) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.
T0717 Enoxacin hydrate CI-919 hydrate,Enoxacin Sesquihydrate,AT-2266 hydrate DNA gyrase , DNA/RNA Synthesis , Topoisomerase , Antibacterial , Antibiotic
Enoxacin hydrate (AT-2266 hydrate) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent.
T15139 DLin-KC2-DMA Others
DLin-KC2-DMA is a cationic/ionizable lipid. Which is used for siRNA delivery.
T5823 D-Lin-MC3-DMA Others
D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.
T31546 DLinDAP D-Lin-DAP,D-LinDAP Others
DLinDAP (D-LinDAP) is an ionizable cationic lipid used for SiRNA delivery.
T13254L UNC10217938A HCl UNC10217938A HCl(1347749-97-6 Free base),UNC7938 HCl Others
UNC10217938A HCl (UNC7938 HCl) is a 3-deazapteridine analog. UNC10217938A HCl exhibits strong oligonucleotide enhancing effects. UNC10217938A HCl can modulate their intracellular trafficking and release from endosomes, l...
T15140 DLinDMA Others
DLinDMA, as a benchmark, is a key stable nucleic acid lipid particleslipid component.
T8902 DOTMA Trimethyl[2,3-(dioleyloxy)propyl]ammonium Chloride,N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium Others
DOTMA (N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium) is a tetra-methylated DOTA analogue. DOTMA is a cationic lipid and can be used as a non-viral vector for gene therapy. It has been used as a component in lipos...
T9098 DMG-PEG 2000 DMG-PEG2000 Others
DMG-PEG 2000 (DMG-PEG2000) is a lipid excipient that has been used in combination with other lipids in the formation of lipid nanoparticles. Formulations containing DMG-PEG 2000 have been used in the development of lipid...
T64293 SLN124
SLN124 is a GalNac-siRNA that targets transmembrane serine protease 6 (Tmprss6) and consists of a trimeric GalNAc ligand bound to TMPRSS6-siRNA. SLN124 has the potential to be used as an siRNA agent to restore ferroregul...
T74447 503O13
503O13 is a degradable ionizable lipid for siRNA delivery.
T39122 Inclisiran ALN-PCSsc
Inclisiran (ALN-PCSsc) is a double-stranded small interfering RNA (siRNA) compound that effectively suppresses PCSK-9 transcription. It proves promising in the investigation of hyperlipidemia and cardiovascular disease (...
T74423 Xalnesiran sodium
Xalnesiran (sodium) is siRNA for the treatment of chronic hepatitis B ( HBV )..
T82481 Elebsiran sodium VIR-2218 sodium
Elebsiran sodium is an siRNA targeting hepatitis B and D virus infections [1].
T37035 HAPC-Chol
HAPC-Chol is a cationic cholesterol. HAPC-Chol, as part of a lipoplex with DOPE , has been used for siRNA delivery and gene silencing in MCF-7 cells in a luciferase assay without affecting cell viability. It has also bee...
T74431 Cemdisiran
Cemdisiran, a conjugated siRNA with N-acetylgalactosamine (GalNAc), targets the liver to inhibit the production of complement 5 (C5) protein, serving as a potential therapeutic agent for the study of complement-mediated ...
T39304 Vutrisiran ALN-TTRsc02
Vutrisiran (ALN-TTRsc02) is an investigational, liver-directed small interfering ribonucleic acid (siRNA) compound designed for research on transthyretin (TTR)-mediated amyloidosis.
T40203 AZD-CO-Ph-PEG4-Ph-CO-AZD AZD-CO-Ph-PEG4-Ph-CO-AZD
AZD-CO-Ph-PEG4-Ph-CO-AZD is a bis-β-lactam linker, commonly employed in the synthesis of antibody-siRNA conjugates.
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