Powder: -20°C for 3 years | In solvent: -80°C for 2 years
D-Lin-MC3-DMA, an ionizable cationic Lipid, is a potent siRNA delivery vehicle.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 34.00 | |
2 mg | In stock | $ 48.00 | |
5 mg | In stock | $ 79.00 | |
10 mg | In stock | $ 117.00 | |
25 mg | In stock | $ 228.00 | |
50 mg | In stock | $ 349.00 | |
100 mg | In stock | $ 523.00 | |
500 mg | In stock | $ 1,170.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 113.00 |
Description | D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle. |
In vitro | Replacement of DSPC by unsaturated PCs and DLin-MC3-DMA by the related lipid DLin-KC2-DMA resulted in highly potent transfection reagents for HeLa cells in vitro. |
Cell Research | White leghorn chicken embryos at stage 24 (30) were removed and dissected in Hanks buffered saline solution (HBSS).?Forelimbs were pooled and treated for 1 h in dispase to remove epithelial ectoderm.?Limb mesenchyme was dissociated, and resuspended in DMEM with 5% FBS and 1% penicillin/streptomycin.?Cells were plated onto 96-well plates at a density of 2x10^5 or 2x10^7 cells/ml and treated with 0-40 μg/ml LNP-pDNA.?Cultures were incubated overnight at 37℃ and resuspended in PBS buffer for expression analysis using a BD LSRII flow cytometer.?Cell survival was assessed in low-density cultures after 24 h of treatment, by counting the adherent cells remaining after PBS washes.?Viability was determined based on average counts of all adherent cells within a single field of view (100x) normalized to cell counts of untreated cultures. |
Molecular Weight | 642.1 |
Formula | C43H79NO2 |
CAS No. | 1224606-06-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 2 years
Ethanol: 16.67 mg/mL (25.96 mM)
DMSO: 43.33 mg/mL (67.48 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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D-Lin-MC3-DMA 1224606-06-7 Others Inhibitor D-Lin-MC-3-DMA D Lin MC3 DMA inhibit DLinMC3DMA inhibitor