salivary — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T0099	Tolterodine tartrate	Detrol LA,PNU-200583E,Kabi-2234	AChR
	Tolterodine tartrate (PNU-200583E) is a potent antagonist for muscarinic receptor. It show selectivity for the urinary bladder and salivary glands in vivo.		AChR
T4579	Pentagastrin	ICI-50123	Others , cholecystokinin
	Pentagastrin (ICI-50123) is a synthetic polypeptide that has effects like gastrin when given parenterally, which can cause the secretion and synthesis of salivary proteins.		Others , cholecystokinin
T38089	2F-Peracetyl-Fucose	1,3,4-Tri-O-acetyl-2-deoxy-2-fluoro-L-fucopyranos	Others
	2F-Peracetyl-Fucose (1,3,4-Tri-O-acetyl-2-deoxy-2-fluoro-L-fucopyranos) is a potent fucosyltransferase (FUT) inhibitor that inhibits salivary acidification and fucosylation in an in vitro inflammatory model.		Others
T25913L	P-113 acetate		HIV Protease , Antibacterial , Antibiotic
	P-113 acetate is an antimicrobial peptide (AMP) derived from the human salivary protein histatin 5, shows good safety and efficacy profiles in gingivitis and human immunodeficiency virus (HIV) patients with oral candidia...		HIV Protease , Antibacterial , Antibiotic
T8832	Eledoisin trifluoroacetate (69-25-0 free base)	Eledoisin trifluoroacetate	Others
	Eledoisin trifluoroacetate (69-25-0 free base) is a peptide extracted from the posterior salivary glands of certain small octopi (Eledone spp., Mollusca), or obtained by synthesis. Its actions resemble those of SUBSTANCE...		Others
T0962	L-Hyoscyamine	Daturine,Hyoscyamine	AChR
	L-Hyoscyamine (Daturine) functions as a non-selective, competitive antagonist of muscarinic receptors, thereby inhibiting the parasympathetic activities of acetylcholine on the salivary, bronchial, and sweat glands, as w...		AChR
T9417L	Gamma-preprotachykinin amide (72-92) acetate	gamma-preprotachykinin amide (72-92) acetate (114882-65-4 Free base)	Others
	gamma-preprotachykinin amide (72-92) acetate is a 21 amino acid peptide belonging to the tachykinin (TK) family and including neurokinin A (NKA) in its C-terminal sequence. gamma-preprotachykinin amide (72-92) acetate po...		Others
T4S1619	L-Hyoscyamine sulfate	Hyoscyamine sulfate hydrate,Levsin Sulfate,Hyoscyamine Sulphate	AChR
	L-Hyoscyamine sulfate (Levsin Sulfate) is the sulfate salt of a belladonna alkaloid derivative and the levorotatory form of racemic atropine isolated from the plants Hyoscyamus niger or Atropa belladonna, which exhibits ...		AChR
T20131	Cevimeline hydrochloride	Cevimeline HCl,Evoxac
	Cevimeline HCl is an agonist of cholinergic that binds to muscarinic receptors. Muscarinic agonists in sufficient dosage can enhance the secretion of exocrine glands, such as salivary and sweat glands.
T21119	Cevimeline	AF-102B,FKS 508,SNI 2011,HSDB 7286
	Cevimeline, a parasympathomimetic and muscarinic agonist, affects M1 and M3 receptors. Cevimeline has been shown to treat dry mouth and Sj gren's syndrome. It is also used to reduce Xerostomia symptoms and increase saliv...
TP1741	Histatin 5
	Histatin 5 inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μM, respectively. Histatin 5 is a human basic salivary peptide with strong fungicidal properties in vitro...
T37834	G3-CNP
	G3-CNP is a colorimetric substrate for α-amylases.1Upon hydrolysis by α-amylases, 2-chloro-4-nitrophenol is released which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity. G3-CNP has...
T83715	Histatin 3 TFA	Hst-3
	Histatin 3, a salivary antimicrobial peptide, exhibits activity against C. albicans with an LC50 of 9.2 µM. Additionally, at a concentration of 12 µM, it promotes actin polymerization in cell-free assays.
T78627	Chinese gallotannin		Others
	Chinese gallotannin, a non-specific promiscuous inhibitor of α-amylase, exhibits a K(i) value of 0.82 μg/mL against human salivary α-amylase and shows potential for diabetes research [1].		Others
T76467	Acetyl-Adhesin (1025-1044) amide
	Acetyl-Adhesin (1025-1044) amide, a 20-peptide fragment derived from the cell surface adhesin of Streptococcus pyogenes, functions as an antimicrobial peptide. It specifically prevents Streptococcus pyogenes recolonizati...
T16547	PK14105		Others
	PK14105 has been evaluated biologically as a potential radioligand for positron emission tomography (PET) studies targeting peripheral benzodiazepine binding sites (PBBS) receptors. When administered to rats with unilate...		Others
T82217	Helospectin I
	Helospectin I, a neuropeptide belonging to the vasoactive intestinal peptide (VIP) family, exhibits vasodilatory and antihypertensive properties, effectively reducing blood pressure. It was initially isolated from the sa...
T82216	Helospectin II
	Helospectin II, a member of the vasoactive intestinal peptide (VIP) family, exhibits vasodilatory and antihypertensive properties that reduce blood pressure. This neuropeptide was initially isolated from the venom of the...
T83689	Histatin 8 TFA	Hst-8
	Histatin 8, a salivary antimicrobial peptide derived from proteolytic fragments of histatin 3 and histatin 5, exhibits activity against A. baumannii strains, both colistin-susceptible and -resistant, at a concentration o...