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Search Results for " repressive "

10

Compounds

Cat No. Product Name Synonyms Targets
T7833 TLX agonist 1 Others
TLX agonist 1 is an orphan nuclear receptor tailless (TLX, NR2E1) modulator
T13954 UNC6852 Histone Methyltransferase , Ligands for Target Protein for PROTAC
UNC6852 contains an EED ligand (IC50 = 247 nM) and a von Hippel-Lindau ligand and is a selective polycomb repressive complex 2 (PRC2) degrader based on PROTAC.
T13974 ZL0580 Epigenetic Reader Domain , HIV Protease
ZL0580 induces HIV suppression by inhibiting Tat transactivation and transcription elongation as well as by inducing repressive chromatin structure at the HIV promoter.
T10205 A-395 Histone Methyltransferase
A-395 is an antagonist of polycomb repressive complex 2 (PRC2) protein-protein interactions that potently inhibits the trimeric PRC2 complex (EZH2-EED-SUZ12, IC50: 18 nM).
T17002 Tazemetostat hydrobromide E-7438 hydrobromide,EPZ-6438 hydrobromide Histone Methyltransferase
Tazemetostat hydrobromide (E-7438 hydrobromide) is a potent and selective EZH2 inhibitor. Tazemetostat hydrobromide inhibits the activity of human polycomb repressive complex 2 (PRC2)-containing wild-type EZH2 (Ki: 2.5 n...
T29231 ZLD1039 ZLD-1039,ZLD 1039 Histone Methyltransferase
ZLD1039 is a potent, orally bioavailable EZH2 (Enhancer of Zeste Homolog 2) inhibitor with high selectivity. It demonstrates strong, concentration-dependent inhibition of both wild-type and mutant (Y641F and A677G) PRC2 ...
T61825 EED ligand 1
EED ligand 1 is a highly versatile, potent, and effective inhibitor that specifically targets the EED subunit of the polycomb repressive complex 2 (PRC2) methyltransferase.
T12554 PROTAC EED degrader-2 Others
PROTAC EED degrader-2 is a PROTAC targeting EED (pKD of 9.27),is a inhibitor of polycomb repressive complex 2 (PRC2) with pIC50 of 8.11.
T12553 PROTAC EED degrader-1 Others
PROTAC EED degrader-1 is a PROTAC targeting EED (pKD = 9.02), is a inhibitor of polycomb repressive complex 2 (PRC2) with pIC50 of 8.17.
T36627 Lysine-specific Demethylase Inhibitor (1C) (hydrochloride)
Lysine-specific demethylase inhibitor (1C) (LSD inhibitor (1C)) is an inhibitor of LSD1, a repressive demethylase selective for histone H3 lysine 4 (H3K4).1,2LSD inhibitor (1C) inhibits LSD1 activity by 85.9% when used a...
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