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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T7833 | TLX agonist 1 | Others | |
TLX agonist 1 is an orphan nuclear receptor tailless (TLX, NR2E1) modulator | |||
T13954 | UNC6852 | Histone Methyltransferase , Ligands for Target Protein for PROTAC | |
UNC6852 contains an EED ligand (IC50 = 247 nM) and a von Hippel-Lindau ligand and is a selective polycomb repressive complex 2 (PRC2) degrader based on PROTAC. | |||
T13974 | ZL0580 | Epigenetic Reader Domain , HIV Protease | |
ZL0580 induces HIV suppression by inhibiting Tat transactivation and transcription elongation as well as by inducing repressive chromatin structure at the HIV promoter. | |||
T10205 | A-395 | Histone Methyltransferase | |
A-395 is an antagonist of polycomb repressive complex 2 (PRC2) protein-protein interactions that potently inhibits the trimeric PRC2 complex (EZH2-EED-SUZ12, IC50: 18 nM). | |||
T17002 | Tazemetostat hydrobromide | E-7438 hydrobromide,EPZ-6438 hydrobromide | Histone Methyltransferase |
Tazemetostat hydrobromide (E-7438 hydrobromide) is a potent and selective EZH2 inhibitor. Tazemetostat hydrobromide inhibits the activity of human polycomb repressive complex 2 (PRC2)-containing wild-type EZH2 (Ki: 2.5 n... | |||
T29231 | ZLD1039 | ZLD-1039,ZLD 1039 | Histone Methyltransferase |
ZLD1039 is a potent, orally bioavailable EZH2 (Enhancer of Zeste Homolog 2) inhibitor with high selectivity. It demonstrates strong, concentration-dependent inhibition of both wild-type and mutant (Y641F and A677G) PRC2 ... | |||
T61825 | EED ligand 1 | ||
EED ligand 1 is a highly versatile, potent, and effective inhibitor that specifically targets the EED subunit of the polycomb repressive complex 2 (PRC2) methyltransferase. | |||
T12554 | PROTAC EED degrader-2 | Others | |
PROTAC EED degrader-2 is a PROTAC targeting EED (pKD of 9.27),is a inhibitor of polycomb repressive complex 2 (PRC2) with pIC50 of 8.11. | |||
T12553 | PROTAC EED degrader-1 | Others | |
PROTAC EED degrader-1 is a PROTAC targeting EED (pKD = 9.02), is a inhibitor of polycomb repressive complex 2 (PRC2) with pIC50 of 8.17. | |||
T36627 | Lysine-specific Demethylase Inhibitor (1C) (hydrochloride) | ||
Lysine-specific demethylase inhibitor (1C) (LSD inhibitor (1C)) is an inhibitor of LSD1, a repressive demethylase selective for histone H3 lysine 4 (H3K4).1,2LSD inhibitor (1C) inhibits LSD1 activity by 85.9% when used a... |