radiolabeled — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T15684	L-689560		NMDAR , iGluR
	L-689560 is widely used as a radiolabeled ligand in binding studies and used to study the roles of NMDA receptors in normal neurological processes as well as in diseases. At the GluN1 glycine binding site, L-689560 is an...		NMDAR , iGluR
T32237	Isoxaben	EL 107,NA 8318,Isoxaben； EL 107； NA 8318	Cell wall
	Isoxaben (EL 107) is a specific inhibitor of cell wall biosynthesis, often used as a herbicide, that inhibits the incorporation of radiolabeled glucose into acid-insoluble cell wall fractions.		Cell wall
T60336	CCR4 antagonist 3-1		CCR
	CCR4 antagonist 3-1 is a less active chemokine receptor 4 (CCR4) antagonist that inhibits [125I]TARC (thymus and activation-regulated chemokine) with an IC50 value of 1.7 μM. CCR4 antagonist 3-1 inhibits the binding of r...		CCR
T15629	JTE-013		Apoptosis , S1P Receptor , LPL Receptor
	JTE-013 is an effective and specific antagonist of S1P2. JTE-013 suppresses the specific binding of radiolabeled S1P to human and rat S1P2 (IC50s: 17 nM and 22 nM, respectively).		Apoptosis , S1P Receptor , LPL Receptor
T70599	Asem F-18
	Asem F-18 is a radiolabeled antagonist for imaging the α7-nicotinic acetylcholine receptor with PET .
T18926	Biotin-probe 1		Others
	Biotin-probe 1 is a non-radiolabeled probe and can be applied to in situ hybridization.		Others
T31787	Fet F-18	Fet F18,18F-Fluoroethyltyrosine,18F-FET
	Fet F-18 is an amino acid analog radiolabeled with fluorine F-18, a positron-emitting isotope, can be used as a tracer in positron emission tomography (PET).
T24014	Dotanoc	DOTA-Nal3-octreotide,DOTA-NOC
	Dotanoc is a ligand to make gallium Ga 68-DOTANOC, which is a gallium Ga 68-radiolabeled analog of somatostatin.
T80157	DOTA-JR11
	DOTA-JR11 is a somatostatin receptor 2 (SSTR2) antagonist that can be radiolabeled with 68Ga. It is utilized for paired imaging in the study of neuroendocrine tumors (NETs) [1].
T80238	NODAGA-LM3 TFA
	NODAGA-LM3 TFA, a SSTR2 antagonist, can be radiolabeled with ^68Ga for PET imaging applications, particularly in the visualization of SSTR-positive paragangliomas [1] [2].
T68873	Cornigerine
	Cornigerine is a natural product analog of colchicine produced by Colchicum cornigerum that inhibited tubulin polymerization both with and without microtubule-associated proteins, inhibited the binding of radiolabeled co...
T37275	2,3-dinor-11β-Prostaglandin F2α	2,3-dinor-11β-Prostaglandin F2α
	2,3-dinor-11β-Prostaglandin F2α (2,3-dinor-11β-PGF2α) was recovered from the urine of both normal monkeys and humans when infused with radiolabeled PGD2, where it represented approximately 1% and 4% of the infused radiol...
T35448	10-Thiastearic Acid
	Heteroatom-substituted fatty acids have been observed to modulate the extension and desaturating of fatty acids, and to influence their distribution within phospholipids pools. 10-Thiastearic acid inhibits desaturation o...
T39545	MK-6884
	MK-6884, a positive allosteric modulator (PAM) of M4 muscarinic receptors, exhibits a high affinity (Ki = 0.19 nM). It is a valuable compound for the investigation of neurodegenerative diseases. Additionally, MK-6884 can...
T68714	Iobenguane I 131
	Iobenguane I 131 is a guanidine analog with specific affinity for tissues of the sympathetic nervous system and related tumors. The radiolabeled forms are used as antineoplastic agents and radioactive imaging agents. MIB...
T61087	THK-5105
	THK-5105, an arylquinoline derivative, demonstrates a high binding affinity for tau fibrils, protein aggregates, and tau-rich Alzheimer's disease (AD) brain homogenates, indicative of its potential as a tau imaging PET (...
T75252	Gemcitabine triphosphate
	Gemcitabine triphosphate (dFdCTP), alongside its counterpart, the active diphosphate (dFdCDP), represents one of the two primary nucleoside metabolites of Gemcitabine within cellular structures. It serves as a benchmark ...
T76253	WL12
	WL12 is a peptide that targets and binds specifically to programmed death ligand 1 (PD-L1). It can be radiolabeled with various radionuclides to produce radiotracers, enabling the evaluation of PD-L1 expression in tumors...
T69712	Icapamespib HCl
	Icapamespib, also known as PU-HZ 151, is a heat shock protein 90 (HSP90) inhibitor. PU-HZ151 showed EC50 of 5 nM in the FP assay as compared to 11 nM for PU-H71 and a logD of 2.37 as compared to 1.21 for PU-H71. PU-HZ...
T70865	BMY-42393
	BMY-42393 is orally active and selective platelet aggregation inhibitor. BMY-42393 is also a prostacyclin partial agonist that inhibited ADP, collagen and thrombin-induced platelet aggregation (IC50 range 0.3 - 2.0 mic...