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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T22676 | Prothrombin (474-477) [Mus musculus] | Others | |
Prothrombin (coagulation factor II) is produced in the liver and is post-translationally modified in a vitamin K-dependent reaction that converts ten glutamic acids on prothrombin into gamma-carboxyglutamic acid. Prothro... | |||
T31206 | Darexaban | YM 150,Darexaban, Tanexaban,YM150 | Factor Xa |
Darexaban (Tanexaban, YM-150) is a direct inhibitor of Factor Xa.Darexaban and Darexaban glucuronide selectively and competitively inhibit FXA and inhibit prothrombin activity at the site of blood clot (thrombus) formati... | |||
T1736 | Apixaban | BMS-562247-01 | Factor Xa |
Apixaban (BMS-562247-01) is an orally active inhibitor of coagulation factor Xa with anticoagulant activity. Apixaban directly inhibits factor Xa, thereby interfering with the conversion of prothrombin to thrombin and pr... | |||
T0809 | Dicoumarol | Dicumarol | Dehydrogenase , NADPH , PDK |
Dicoumarol (Dicumarol) is a hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicoumarol is a competitive inhibitor of vitamin K epoxidereductase; t... | |||
T1184 | Rivaroxaban | BAY 59-7939 | Factor Xa , Thrombin |
Rivaroxaban (BAY 59-7939) is an orally bioavailable oxazolidinone derivative and direct inhibitor of the coagulation factor Xa with anticoagulant activity. Upon oral administration, rivaroxaban selectively binds to both ... | |||
T20616 | Coumachlor | G-23133,Ratilan,G23133,Tomorin,G 23133 | |
Coumachlor, a first-generation anticoagulant rodenticide, blocks the formation of prothrombin and inhibits blood coagulation causing internal haemorrhage. | |||
TP1853 | TP508 | ||
TP508 is a 23 amino acid synthetic peptide representing residues 508-530 of human prothrombin which is identified as a potential receptor-binding domain based on competition for high-affinity thrombin binding to fibrobla... | |||
TP2234 | Coagulation factor II (thrombin) B chain fragment [Homo sapiens] | Others | |
Thrombin is a "trypsin-like" serine protease that is encoded by the F2 gene in humans. Thrombin is produced by the enzymatic cleavage of two sites on prothrombin by activated Factor X (Xa). Thrombin in turn acts as a ser... | |||
T75589 | Bitis Cornuta Venom | ||
Bitis Cornuta (Many-horned Adder) Venom, sourced from Bitis Cornuta, comprises snake venom phospholipase A2 (sPLA2) toxins that exhibit anticoagulant properties by inhibiting the prothrombinase complex, consequently prom... | |||
T27698 | JTV-803 mesylate | JTV803,JTV 803,JTV-803 | |
JTV-803 is a factor Xa inhibitor. JTV-803 showed a competitive inhibitory effect on human factor Xa, with a K(i) value of 0.019 microM and IC(50) value of 0.081 microM. JTV-803 was 100 times more selective in inhibiting ... | |||
T36203 | Menaquinone 9 | MK-9,Vitamin K2(45),Menaquinone 9 | |
Menaquinone 9 (MK-9) is a vitamin K2 analog that has been found in various bacteria, including E. coli. MK-9 is UV-sensitive and binds to soluble nitrate reductase, a component of the bacterial electron transport chain. ... |