prostanoid — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T1626	Prostaglandin E1	PGE1,Alprostadil	Endogenous Metabolite , Prostaglandin Receptor
	Prostaglandin E1 (Alprostadil) is the naturally occurring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Prostaglandin E1 is a potent vasodilator agent that increases peripheral blood flow, in...		Endogenous Metabolite , Prostaglandin Receptor
T17232	Vidupiprant	AMG 853	Prostaglandin Receptor
	Vidupiprant (AMG 853) is an effective dual antagonist of CRTH2 and prostanoid D receptor with IC50s of 8 nM and 35 nM in human plasma. Vidupiprant can be used in studies about the treatment of asthma.		Prostaglandin Receptor
T4635	Ralinepag	APD811	Others , Prostaglandin Receptor
	Ralinepag (APD811) is a potent, orally bioavailable agonist of non-prostanoid prostacyclin (IP) receptor, with EC50s of 8.5 nM, 530 nM and 850 nM for human and rat IP receptor and human DP1 receptor, respectively.		Others , Prostaglandin Receptor
T2528	Latanoprost	Xalatan,PHXA41	GPR , Prostaglandin Receptor , RAR/RXR
	Latanoprost (Xalatan) is a prostaglandin F2alpha analogue and a prostanoid selective FP receptor agonist with an ocular hypertensive effect.		GPR , Prostaglandin Receptor , RAR/RXR
T1978	GW627368	GW 627368X	Prostaglandin Receptor
	GW627368 (GW 627368X)X is a novel, potent and selective antagonist of prostanoid EP4 receptor.		Prostaglandin Receptor
T11211	EP4 receptor antagonist 1		Prostaglandin Receptor
	EP4 Receptor Antagonist 1 is a highly potent and selective competitive prostanoid EP4 receptor antagonist, effective for cancer immunotherapy. It inhibits both human and mouse EP4 receptors with IC50 values of 6.1 nM and...		Prostaglandin Receptor
T2664	Timapiprant	OC000459	GPR , Prostaglandin Receptor
	Timapiprant (OC000459) is a potent and selective D prostanoid receptor 2 (DP2) antagonist (IC50: 13 nM).		GPR , Prostaglandin Receptor
T15718	Latanoprost acid		GPR
	Latanoprost acid is a selective agonist of prostanoid receptors and inhibits RANKL-induced osteoclastogenesis and function through the inhibition of c-fos/NFATc1 pathway. Latanoprost acid can be used in studies about low...		GPR
T69602	ONO-DI-004
	ONO-DI-004 is a selective EP1 Prostanoid receptor agonist.
T26578	AH13205	AH-13205,AH 13205
	AH13205 is an agonist of EP2 prostanoid receptor.
T29813	AL-3138	AL3138,AL 3138,11-Deoxy-16-fluoro PGF2alpha
	AL-3138 is a prostaglandin F2alpha (PGF2alpha) analogue which antagonizes FP prostanoid receptor-mediated inositol phosphates generation.
T27765	L-644,698
	L-644,698 is a selective agonist of human prostanoid DP receptor.
T20644	Unoprostone isopropyl	UF021,Rescula,UF-021,UF 021
	Unoprostone isopropyl, a prostanoid and synthetic docosanoid, is approved for the treatment of ocular hypertension and open-angle glaucoma.
T19660	QCC-374	QCC374
	QCC-374 is a prostanoid agonist. It potentially for the treatment of pulmonary arterial hypertension.
T27875	LY 150310	LY150310,LY-150310
	LY 150310, a histamine H1-receptor antagonist, can alter prostanoid concentrations in vitro and in vivo.
T28651	S-5751	S 5751
	S-5751, a prostanoid DP (DP1) antagonist, is used potentially for the treatment of bronchial asthma.
T29734	AH 19437	AH-19437,AH19437
	AH 19437 is a prostanoid receptor.
T15690	L-902688		Prostaglandin Receptor
	L-902688 is an orally active EP4 receptor agonist (Ki: 0.38 nM; EC50: 0.6 nM). L-902688 displays >4,000-fold selective for EP4 over other EP and prostanoid receptors.		Prostaglandin Receptor
T28032	MF266-1	MF 266-1,MF-266-1
	MF266-1, a selective E prostanoid receptor 4 antagonist, relieves joint inflammation and pain in rodent models of osteoarthritis and rheumatoid.
T16389	Omidenepag		Prostaglandin Receptor
	Omidenepag is a pharmacologically active form of Omidenepag Isopropyl and is a selective, non-prostanoid EP2 receptor agonist (EC50: 1.1 nM). Omidenepag displays binding affinities (IC50: 10 nM for h-EP2).		Prostaglandin Receptor