Home Tools
Log in
Cart

Search Result

Search Results for " proliferating-cell "

6

Compounds

Cat No. Product Name Synonyms Targets
T11546 HDHODH-IN-1 Dehydrogenase
hDHODH-IN-1 is a human dihydroorotate dehydrogenase (hDHODH) inhibitor with an anti-inflammatory effect.
T10343 AOH1160 N-(2-Oxo-2-(2-phenoxyphenylamino)ethyl)-1-naphthamide Apoptosis , DNA/RNA Synthesis
AOH1160 is an inhibitor of proliferating cell nuclear antigen (PCNA). AOH1160 induces apoptosis and causes cell-cycle arrest by interfering with DNA replication.
T35719 T2AA T2AA,4-[4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy]phenol,ZINC95605533 DNA/RNA Synthesis
T2AA (4-[4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy]phenol) is an inhibitor of proliferating cell nuclear antigen (PCNA) with IC50 of 1 μM for PCNA/PIP-box peptide interaction. T2AA suppresses cancer cell growth ...
T77520 AOH1996 Apoptosis , DNA/RNA Synthesis
AOH1996 is an orally active ligand for the replicasome component PCNA (proliferating cell nuclear antigen), targeting the transcription-replication conflict (TRC).AOH1996 interferes with the interaction of PCNA with its ...
T0798 Triamcinolone Fluoxyprednisolone,Aristocort,Rodinolone Glucocorticoid Receptor , COX
Triamcinolone (Aristocort) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. Upon cell entry, triamcinolone binds to and activates the glucocorticoid receptor, which leads to transloca...
T79293 EGFR-IN-79 EGFR
EGFR-IN-79 (compound 21), an EGFR inhibitor, exhibits antitumor activity through ROS-independent apoptosis and EGFR/AKT/mTOR-mediated autophagy. It effectively induces cell death in proliferating and quiescent zones of E...
TargetMol