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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11546 | HDHODH-IN-1 | Dehydrogenase | |
hDHODH-IN-1 is a human dihydroorotate dehydrogenase (hDHODH) inhibitor with an anti-inflammatory effect. | |||
T10343 | AOH1160 | N-(2-Oxo-2-(2-phenoxyphenylamino)ethyl)-1-naphthamide | Apoptosis , DNA/RNA Synthesis |
AOH1160 is an inhibitor of proliferating cell nuclear antigen (PCNA). AOH1160 induces apoptosis and causes cell-cycle arrest by interfering with DNA replication. | |||
T35719 | T2AA | T2AA,4-[4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy]phenol,ZINC95605533 | DNA/RNA Synthesis |
T2AA (4-[4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy]phenol) is an inhibitor of proliferating cell nuclear antigen (PCNA) with IC50 of 1 μM for PCNA/PIP-box peptide interaction. T2AA suppresses cancer cell growth ... | |||
T77520 | AOH1996 | Apoptosis , DNA/RNA Synthesis | |
AOH1996 is an orally active ligand for the replicasome component PCNA (proliferating cell nuclear antigen), targeting the transcription-replication conflict (TRC).AOH1996 interferes with the interaction of PCNA with its ... | |||
T0798 | Triamcinolone | Fluoxyprednisolone,Aristocort,Rodinolone | Glucocorticoid Receptor , COX |
Triamcinolone (Aristocort) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. Upon cell entry, triamcinolone binds to and activates the glucocorticoid receptor, which leads to transloca... | |||
T79293 | EGFR-IN-79 | EGFR | |
EGFR-IN-79 (compound 21), an EGFR inhibitor, exhibits antitumor activity through ROS-independent apoptosis and EGFR/AKT/mTOR-mediated autophagy. It effectively induces cell death in proliferating and quiescent zones of E... |