14
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T69033 | Magnesium Oxaloacetate | ||
Magnesium Oxaloacetate is an inhibitor of the amebicidal activity of activated murine macrophages, helping the parasite to survive within the mouse large intestine and increasing the survival of C. elegans exposed to H2O... | |||
T8765 | IGOT1-01 | Others | |
iGOT1-01 is an effective inhibitor of glutamate oxaloacetate transaminase 1(GOT1) . iGOT1-01 has IC50s of 84.6 μM and 11.3 μM in GOT1/MDH1 assay and GOT1/GLOX/HRP assay, respectively. iGOT1-01 can be used in anti-cancer ... | |||
T8766 | GOT1 inhibitor-1 | GOT1 inhibitor 2c | Others |
GOT1 inhibitor-1 (GOT1 inhibitor 2c) is a novel, potent and non-covalent inhibitor of glutamate oxaloacetate transaminase 1 (GOT1) with an IC50 of 8.2 uM. | |||
T12045 | (-)-Hydroxycitric acid lactone | Garcinia lactone | ATP Citrate Lyase |
(-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent.(-)-Hydroxycitric acid lactone was a potent inhibitor of ATP citrate lyase, which catalyzes the extramitochondrial cleavage of citrate to oxaloac... | |||
T4862 | Oxaloacetic acid | Endogenous Metabolite | |
Oxaloacetic acid, also known as oxosuccinic acid or oxalacetic acid, is a four-carbon dicarboxylic acid appearing as an intermediate of the citric acid cycle. In vivo, oxaloacetate (the ionized form of oxaloacetic acid) ... | |||
T4838 | (S)-Malic acid | L-(-)-Malic acid,(S)-(-)-HYDROXYSUCCINIC ACID,(S)-2-Hydroxysuccinic acid | Others , Endogenous Metabolite |
(S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a tart-tasting organic dicarboxylic acid that plays a role in many sour or tart foods. Apples contain malic acid, which contributes to the sourness of a green apple. Malic a... | |||
T76118 | Malate dehydrogenase | ||
Malate dehydrogenase catalyzes the mutual conversion of oxaloacetate and malate, and is associated with the oxidation/reduction of dinucleotide coenzymes [1] . | |||
T69068 | Aspulvinone H | ||
Aspulvinone H is a natural inhibitor of glutamic oxaloacetate transaminase 1 (GOT1), suppressing glutamine metabolism, making PDAC cells sensitive to oxidative stress and inhibiting cell proliferation, exhibiting potent ... | |||
TN1751 | Hydroxycitric acid | ERK , p38 MAPK , Fatty Acid Synthase | |
(-)-Hydroxycitric acid (HCA) can inhibit fat synthesis and reduces food intake, the primary mechanism of action of HCA appears to be related to its ability to act as a competitive inhibitor of the enzyme ATP-citrate lyas... | |||
T76178 | Aspartate aminotransferase | ||
Aspartate aminotransferase (AST) is a transaminase enzyme, is often used in biochemical studies. Aspartate aminotransferase catalyzes aspartate and alpha-ketoglutarate converts to oxaloacetate and glutamate. Aspartate am... | |||
T71305 | Clofibric Acid-d4 | ||
Clofibric acid-d4 is intended for use as an internal standard for the quantification of clofibric acid by GC- or LC-MS. Clofibric acid is a peroxisome proliferator-activated receptor α (PPARα) agonist (EC50 = 50 µM in a ... | |||
T80060 | Pyruvate carboxylase | Endogenous Metabolite | |
Pyruvate carboxylase, a biotin-containing enzyme, catalyzes the carboxylation of pyruvate to oxaloacetate, a reaction dependent on HCO3− and MgATP. This enzyme is crucial for regulating whole-body energetics, influencing... | |||
T78351 | Phosphoenolpyruvate carboxylase | PEPC | |
Phosphoenolpyruvate carboxylase (PEPC) is an enzyme that irreversibly catalyzes the conversion of phosphoenolpyruvate and bicarbonate to oxaloacetate and inorganic phosphorus in the presence of Mg2+. It is essential for ... | |||
T65396 | Piperazine 2HCl | ||
Piperazine (2HCl) is gamma-aminobutyric acid (GABA) agonists and its major effects appear to be on the central nervous system. Piperazine was the anthelmintic with the greatest number of reports of toxicoses and suspecte... |