latent — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TP1268	CEF19, Epstein-Barr Virus latent NA-3A (458-466)	CEF19,Epstein-Barr Virus latent NA-3A 458-466
	CEF19, Epstein-Barr Virus latent NA-3A (458-466) is a single peptide epitope, YPLHEQHGM, representing residues 458-466 of the type 1 Epstein-Barr Virus (EBV) nuclear antigen 3A protein (B95.8 strain).
T0850	Primaquine diphosphate	Primaquine phosphate,Primaquine bisphosphate	Antibiotic , Parasite
	Primaquine diphosphate is the phosphate salt form of primaquine, a synthetic, 8-aminoquinoline derivative with antimalarial properties. Although its mechanism of action is unclear, primaquine bind to and alter the proper...		Antibiotic , Parasite
T32668	Leucomalachite green	NSC36379,NSC 36379,NSC-36379	Others
	Leucomalachite green (NSC-36379) is used in detecting latent bloodstains and in the forensic field because of convenience and cost/time-effectiveness.		Others
T10603	BRD-6929		HIV Protease , HDAC
	BRD-6929 is a selective, brain-penetrant HDAC1 and HDAC2 inhibitor (IC50: 1 and 8 nM). BRD-6929 (Cpd-60) shows high-affinity to HDAC1 and HDAC2 (Kis: 0.2 and 1.5 nM) [2]. BRD-6929 potentiates the efficacy of gnidimacrin...		HIV Protease , HDAC
T5S2017	Ingenol	(-)-Ingenol	PKC
	1. Ingenol ((-)-Ingenol) mebutate is an effective treatment for actinic keratosis. 2. Formulating novel derivatives from Ingenol esters may be an innovative approach to develop new lead compounds to reactivate latent HIV...		PKC
T3926	Echinatin	Retrochalcone	Free radical scavengers
	Echinatin (Retrochalcone) disturb the mitochondrial energy transfer reactions and membrane permeability, at a low concentration cause deterioration of respiratory control and oxidative phosphorylation of isolated rat liv...		Free radical scavengers
T27611	Ingenol 3-Hexanoate
	Ingenol 3-Hexanoate is a novel potent reactivator of latent HIV-1.
T28818	SMAPP1
	SMAPP1 is an activator of protein phosphatase 1 (PP1). SMAPP1 induces PP1 activity in vitro and activates latent HIV-1 provirus in cultured and primary T cells.
T61310	HIV-1 inhibitor-37
	HIV-1 inhibitor-37 (Compound 83) is a highly powerful HIV-1 inhibitor. It exhibits significant potential for use as an innovative latent HIV-1 reactivating agent [1].
T27988	MDG486	BAF IN A01,A01,MDG-486,MDG 486,BAF-IN-A01
	MDG486, an inhibitor of BAF, works by activating latent HIV-1.
T40191	17-GMB-APA-GA
	17-GMB-APA-GA, a potent HSP90 inhibitor, is an ADC cytotoxin commonly employed for studying latent T. gondii infection.
T24132	HDAC3-IN-T326	HDAC3 inhibitor-T326,T326,HDAC3 IN T326,HDAC3 inhibitor T326,HDAC3INT326
	HDAC3-IN-T326 is a potent and selective HDAC3 inhibitor that acts by increasing NF-κB acetylation and activating HIV gene expression in latent HIV-infected cells.
T81931	Linavonkibart
	Linavonkibart (SRK 181) is a fully human antibody with high affinity for latent TGFβ1, selectively binding and inhibiting its activation. This compound is significant in the context of cancer [1].
T68502	Dibrospidium Free Base
	Dibrospidium Free Base is a dispirotripiperazine derivative and alkylating agent with potential antineoplastic and anti-inflammatory activities. The duration of DNA synthesis inhibition in tumor cells was found to correl...
T77067	Livmoniplimab
	Livmoniplimab (ABBV-151; ARGX-115), a potent humanized monoclonal antibody targeting LRRC32 (GARP)/TGFβ1, inhibits LRRC32-mediated activation of latent TGFβ1. This compound shows promise for cancer research [1].
T69009	Gnidimacrin
	Gnidimacrin activated HIV-1 replication and killed persistently-infected cells at picomolar concentrations. In addition to its potential to purge HIV-1 from latently infected cells, gnidimacrin potently inhibited a panel...
TN3914	Echinatine		ATPase , IL Receptor , TNF
	Echinatin exerts a protective effect against ischemia/reperfusion (I/R)-induced myocardial injury on hearts, this effect may be attributed to the antioxidant and anti-inflammatory activities of this compound. Echinatin c...		ATPase , IL Receptor , TNF
T73986	ONX-0914 TFA
	ONX-0914 (PR-957) TFA is a selective, noncompetitive, irreversible inhibitor targeting the chymotrypsin-like subunit (LMP7) of the immunoproteasome, effectively blocking cytokine production and mitigating the progression...