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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8682 | Vazegepant hydrochloride | Vazegepant HCl | CGRP Receptor |
Vazegepant hydrochloride (Vazegepant HCl) is the first intranasal gepant for the acute treatment of migraine and has announced a positive phase II/III study. | |||
T21404 | Fluticasone furoate | Veramyst,Allermist,Avamys,Fluticasone furoate | Glucocorticoid Receptor |
Fluticasone furoate (Avamys) is a synthetic trifluorinated corticosteroid derived from fluticasone with a Kd of 0.3 nM. Fluticasone furoate has potent anti-inflammatory, anti-asthmatic activity, and low systemic exposure... | |||
T15257 | Etripamil | MSP-2017,(-)-MSP-2017 | Calcium Channel |
Etripamil (MSP-2017) displays atrioventricular nodal conduction and prolongs atrioventricular nodal refractory periods by inhibiting calcium ion influx through the calcium slow channels in the atrioventricular node cells... | |||
T71012 | Nemazoline Free Base | ||
Nemazoline Free Base is a nasal decongestant. It has alpha 1-agonist/alpha 2-antagonist activity and was more effective and long-acting than oxymetazoline on canine nasal mucosa, in-vitro and in-vivo. Upon intranasal adm... | |||
T38734 | Vazegepant | Zavegepant,BHV-3500 | |
Vazegepant is an intranasal CGRP receptor antagonist utilized for conducting acute migraine research. | |||
T27153 | Dexamethasone cipecilate | NS126,NS-126,NS 126 | |
Dexamethasone cipecilate is a long-acting intranasal corticosteroid and a highly lipophilic anti-inflammatory corticosteroid. | |||
T25437 | Fpl 14294 | Fpl-14294,Fpl14294 | |
Fpl 14294 is a novel CCK-8 agonist with effective intranasal anorectic activity in the rat. | |||
T11482 | GSK2245035 | Others | |
GSK2245035 is a highly selective intranasal TLR7 agonist with preferential Type-1 interferon (IFN)-stimulating properties (pEC50s: 9.3 and 6.5 for IFNα and TFNα). It effectively suppresses allergen-induced Th2 cytokine p... | |||
T38118 | Zanamivir-13C,15N2 | Zanamivir-13C,15N2 | |
Zanamivir-13C,15N2is intended for use as an internal standard for the quantification of zanamivir by GC- or LC-MS. Zanamivir is a sialic acid analog that inhibits neuraminidase release of newly replicated influenza virus... | |||
T36984 | Cyclic di-IMP (sodium salt) | ||
Cyclic di-IMP (sodium salt) (c-di-IMP) is a synthetic second messenger structurally related to the bacterial second messengers cyclic di-GMP and cyclic di-AMP . C-di-IMP has adjuvant properties when co-administered with ... |