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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T76147 | 3α-Hydroxysteroid dehydrogenase | ||
3α-Hydroxysteroid dehydrogenase (3α-HSD), encoded by the AKR1C4 gene, is responsible for catalyzing the transformation of 3-ketosteroids into 3α-hydroxy compounds. This enzyme significantly contributes to the inactivatio... | |||
T2207 | Adrenosterone | 11-ketoandrostenedione,11-oxoandrostenedione,Reichstein's substance G | Androgen Receptor , Endogenous Metabolite |
Adrenosterone (11-ketoandrostenedione) is a steroid hormone isolated from the adrenal cortex. | |||
T68664 | Epostane | Win-32729 | Dehydrogenase |
Epostane (Win-32729) is a 3β-hydroxysteroid dehydrogenase inhibitor that acts by inhibiting the enzyme 3β-hydroxysteroid dehydrogenase, blocking progesterone production. | |||
T14151 | AKR1C1-IN-1 | NADPH | |
AKR1C1-IN-1 is a human 20α-hydroxysteroid dehydrogenase (AKR1C1) inhibitor (Ki: 4 nM for AKR1C1). | |||
T14388 | AZD 4017 | Dehydrogenase | |
AZD 4017 is an inhibitor of 11β-Hydroxysteroid Dehydrogenase Type 1(11β-HSD1) (IC50: 7 nM). | |||
T71394 | BMS-823778 | ||
BMS-823778 is an orally available potent and selective inhibitor of 11-β-hydroxysteroid-dehydrogenase 1 (11βHSD-1). BMS-823778 is a potential therapeutic agent for type 2 diabetes mellitus (T2DM). | |||
T9594 | BI-187004 | Dehydrogenase | |
BI-187004 is an 11β-hydroxysteroid dehydrogenase 1 inhibitor. | |||
T67903 | 11β-HSD1 inibitor 17 | Dehydrogenase | |
11β-HSD1 inibitor 17 is an inhibitor of 11β-hydroxysteroid dehydrogenase (11β-HSD1). | |||
T13100 | TC HSD 21 | Dehydrogenase | |
TC HSD 21 is a potent and highly selective inhibitor of 17β-hydroxysteroid dehydrogenase type 3 (IC50 = 14 nM). | |||
T0238 | 2-(Acetyloxy)-3-Methylbenzoic Acid | Others | |
2-(Acetyloxy)-3-Methylbenzoic Acid is used in qHTS Assay for Inhibitors of hydroxysteroid (17-beta) dehydrogenase 4, HSD17B4 with activity value of 19.95 μM | |||
T3542 | BVT-14225 | BVT 14225 | Dehydrogenase |
BVT-14225 is a selective 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor (IC50=52 nM). | |||
T1473 | Trilostane | Win 24540 | Dehydrogenase |
Trilostane (Win 24540) is a synthetic derivative of androstane with adrenocortical suppressive properties. Trilostane reversibly inhibits 3 beta-hydroxysteroid dehydrogenase delta 5-4 isomerase in the adrenal cortex. | |||
T77576 | 17β-HSD10-IN-1 | Dehydrogenase , Endogenous Metabolite | |
17β-HSD10-IN-1 is an orally available 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10) inhibitor with blood-brain permeability and potency for the study of Alzheimer's disease. | |||
T77606 | WAY-311610 | Dehydrogenase | |
WAY-311610 is an 11β-hydroxysteroid dehydrogenase HSD11B1 inhibitor that inhibits the 11β-HSD1 enzyme with an IC = 0.34 μM.It can be used to study neuropathic pain, inflammatory pain, and occipital neuralgia. | |||
T73446 | BI‑3231 | Dehydrogenase | |
BI‑3231 is a selective and potent inhibitor of hydroxysteroid 17ß-dehydrogenase 13 HSD17B13, inhibiting hHSD17B13 and mHSD17B13.BI-3231 can be used for the study of alcohol-associated liver injury, fibrosis and cirrhosis... | |||
T16510 | PF-915275 | Dehydrogenase | |
The dose-dependent effect of PF-915275 on the conversion of cortisone to cortisol in primary human and monkey hepatocytes (EC50: 20 and 100 nM, respectively). PF-915275 is an effective and selective human 11β-hydroxyster... | |||
TJS0341 | 7-Amino-4-(trifluoromethyl)coumarin | Coumarin 151,AFC | 5-HT Receptor |
7-Amino-4-(trifluoromethyl)coumarin (Coumarin 151) is a 5-Hydroxytryptamine Receptor Subtype 1E (HTR1E) antagonist. 7-Amino-4-(trifluoromethyl)coumarin is a Galanin Receptor 2 (GALR2) antagonist. 7-Amino-4-(trifluorometh... | |||
T22458 | WEHL-04 | 7-Bromo-1,2,3,4-tetrahydroquinoline | Others |
WEHL-04 is an intermediate used to prepare (isoquinolinylsulfonyl)benzoic acids as inhibitors of type 5 71-β-hydroxysteroid dehydrogenase AKR1C3. It is also used in the synthesis of 2-aminooctahydrocyclopentalene-3a-carb... | |||
T0522 | Diammonium Glycyrrhizinate | Glycyrrhizin | Dehydrogenase |
Diammonium Glycyrrhizinate (Glycyrrhizin) , an extensively used anti-inflammatory agent, is isolated from the licorice root. It is metabolized to glycyrrhetinic acid, which inhibits 11-β-hydroxysteroid dehydrogenase and ... | |||
T14001 | 11-Beta-hydroxyandrostenedione | NSC-17102,4-Androsten-11β-ol-3,17-dione | Endogenous Metabolite |
11-Beta-hydroxyandrostenedione (NSC-17102) is a steroid mainly found in the adrenal origin (11β-hydroxylase is present in adrenal tissue, but absent in ovarian tissue), which is a 11β-hydroxysteroid dehydrogenase isozyme... |