hca-i — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T6503	Fluorometholone Acetate	NSC 47438,Flarex,Eflone,Oxylone acetate	Glucocorticoid Receptor , Carbonic Anhydrase
	Fluorometholone Acetate (Oxylone acetate) is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye.		Glucocorticoid Receptor , Carbonic Anhydrase
T63557	hCA I-IN-1
	hCA I-IN-1 is a human carbonic anhydrase I (hCA I) inhibitor that acts on hCA I (Ki: 38.3 nM), hCA II (Ki: 716.4 nM), hCAIX (Ki: 940.1 nM) and hCAXII (Ki: 192.8 nM).
T63972	hCA I-IN-2
	hCA I-IN-2 (Compound 6d) is a selective inhibitor of human carbonic anhydrase I (hCA I) and acts on hCA I (Ki: 18.8 nM), hCA II (Ki: 375.1 nM), hCAIX (Ki: 1721 nM) and hCAXII (Ki: 283.9 nM).
T60450	AChE/hCA I/II-IN-1
	AChE/hCA I/II-IN-1 (Compound 6) is a potent AChE/Hca inhibitor with IC50 values of 22.21, 60.79 and 66.64 nM for AChE, Hca Ⅰ and Hca Ⅱ. AChE/hCA I/II-IN-1 can be used in glaucoma, Alzheimer's disease, and diabetes rsearc...
T63305	Carbonic anhydrase inhibitor 6
	Carbonic anhydrase inhibitor 6 is a potent inhibitor of human carbonic anhydrase (hCA), acting on hCA IX (Ki: 9.7 nM), hCA II (Ki: 35.2 nM), hCA XII (Ki: 88.5 nM) and hCA I (Ki: 91.8 nM).
T77560	Histone acetyltransferase p300 Inhibitor 4c		Carbonic Anhydrase , AChE
	Histone acetyltransferase p300 Inhibitor 4c is a 2-aminothiazole derivative. Histone acetyltransferase p300 Inhibitor 4c inhibited hCA I, hCA II, AChE and BChE with Ki values of 0.008 ± 0.001, 0.124 ± 0.017, 0.129 ± 0.03...		Carbonic Anhydrase , AChE
T61745	hCAI/II-IN-6		Carbonic Anhydrase
	hCAI/II-IN-6 is a selective and orally active inhibitor of human carbonic anhydrase (CA). hCAI/II-IN-6 inhibited hCA I, hCA II, hCA VII, and hCA XII with Ki values of 220, 4.9, 6.5, and ＞50,000 nM. hCAI/II-IN-6 showed an...		Carbonic Anhydrase
T23782	Benzolamide	CL-11366,W 1803,CL 11366,CL11366,W-1803	Carbonic Anhydrase
	Benzolamide (CL 11366) inhibits carbonic anhydrase effectively and low-threshold calcium currents in hippocampal pyramidal neurons.		Carbonic Anhydrase
T35610	2,5-dimethyl Celecoxib		Apoptosis , Wnt/beta-catenin , Prostaglandin Receptor
	2,5-dimethyl Celecoxib is a derivative of celecoxib that does not inhibit COX-2 (IC50 = >100 μM).1 It does inhibit microsomal prostaglandin E synthase-1 (mPGES-1) in HeLa cells (IC50 = 15.6 μM) and reduces prostaglandin ...		Apoptosis , Wnt/beta-catenin , Prostaglandin Receptor
T61263	hCA IX-IN-1
	hCA IX-IN-1 (Compound 6f) is a human carbonic anhydrase ( hCA ) inhibitor with K i values of 331.4, 28.4, 9.4 and 17.8 nM against hCA I, hCA II, hCA IX and hCA XII, respectively. hCA IX-IN-1 shows anticancer activity [1]...
T61282	hCAI/II-IN-2
	hCAI/II-IN-2 (compound 2b) is a highly effective dual inhibitor of human carbonic anhydrase I and II (hCA I/II), with Ki values of 40.97 nM, 15.15 nM, and 61.88 nM for hCA I, hCA II, and hCA IX, respectively. With its an...
T74486	hCAIX-IN-17
	Compound 6f, also known as hCA IX-IN-1, is a human carbonic anhydrase (hCA) inhibitor that exhibits varying inhibitory effectiveness across different hCA isoforms, with K i values of 331.4 nM for hCA I, 28.4 nM for hCA I...
T62666	Carbonic anhydrase inhibitor 7
	Carbonic anhydrase inhibitor 7 is a potent inhibitor of human carbonic anhydrase (hCA), acting on hCA IX (Ki: 6.5 nM), hCA II (Ki: 7.1 nM), hCA XII (Ki: 72.1 nM) and hCA I (Ki: 255.8 nM).
T61842	Carbonic anhydrase inhibitor 14
	Carbonic anhydrase inhibitor 14 (Compound 8b) is a potent CA inhibitor, exhibiting K i values of 1203, 99.7, 9.4, and 27.7 nM against hCA I, hCA II, hCA IX, and hCA XII, respectively. Additionally, it effectively inhibit...
T61832	hCAI/II-IN-3
	hCAI/II-IN-3 (compound 5b) is a highly effective dual inhibitor of hCA I/II enzymes. It exhibits Ki values of 51.25, 13.15, and 42.18 nM for hCA I, hCA II, and hCA Ⅸ, respectively. hCAI/II-IN-3 demonstrates anti-hypoxic ...
T62892	hCAI/II-IN-1
	hCAI/II-IN-1 (Compound 3h) is a human carbonic anhydrase I and II (hCA I/II) inhibitor that acts on hCA I (IC50: 0.047 μM) and hCA II (IC50: 0.024 μM).
T61164	hCAII-IN-3
	hCAII-IN-3 (Compound 16) is an inhibitor of human carbonic anhydrase (hCA). It exhibits high affinity for hCA I, hCA II, hCA IX, and hCA XII, with Ki values of 403.8 nM, 5.1 nM, 10.2 nM, and 5.2 nM, respectively. Notably...
T63764	hCA XII/II/IX-IN-1
	hCA XII/II/IX-IN-1 is a potent inhibitor of human carbonic anhydrase (hCA) and is able to act on hCA I (IC50: 2.6 μM), hCA II (IC50: 0.004 μM), hCA IX (IC50: 0.005 μM) and hCA XII (IC50: 0.001 μM). hCA XII/II/IX -IN-1 ex...
T61980	Carbonic anhydrase inhibitor 8
	Carbonic anhydrase inhibitor 8 (compound R-13) is a potent human carbonic anhydrase (hCA). Carbonic anhydrase inhibitor 8 shows K i values of 60.7 nM, 320.7 nM, 2298 nM for hCA I, hCA II, hCA IV, respectively.
T63631	hCAII-IN-2
	hCAII-IN-2 is a cytoplasmic human carbonic anhydrase (hCA) inhibitor that acts on hCA I (Ki: 261.4 nM), hCA II (Ki: 3.8 nM), hCA IX (Ki: 19.6 nM) and hCA XII (Ki: 45.2 nM).