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Search Results for " glucocorticoid "

20

Compounds

Cat No. Product Name Synonyms Targets
T37908 Glucocorticoid receptor agonist-1 Glucocorticoid Receptor
Glucocorticoid receptor agonist-1 is a potent glucocorticoid receptor agonist with an IC50 of 2.8 nM[1].
T67742 EX-A5386 Glucocorticoid receptor modulator-1 Glucocorticoid Receptor
EX-A5386 (Glucocorticoid receptor modulator-1) is a potent glucocorticoid receptor modulator, IC50/EC50<100nM.
T11417 Glucocorticoid receptor agonist Others
Glucocorticoid receptor agonist is an effective glucocorticoid receptor agonist.
T74697 Glucocorticoid receptor agonist-2
Glucocorticoid receptor agonist-2 (compound 21), a glucocorticoid receptor agonist exhibiting an IC50 value of 6.6 nM, serves as an active reference for ABBV-3373 [1]. This compound is instrumental in the synthesis of an...
T72102 Glucocorticoid receptor modulator 1
Glucocorticoid receptor modulator 1 is a potent, orally active, non-steroidal selective glucocorticoid receptor modulator, exhibiting IC50 values of 9 nM and 130 nM against NF-κB and AP-1, respectively. It effectively re...
T63551 Glucocorticoid receptor-IN-1
Glucocorticoid receptor-IN-1 is a selective regulator of the glucocorticoid receptor (GR) and exhibits anti-inflammatory activity. glucocorticoid receptor-IN-1 has good transcriptional repression, acting on hMMP1 ( IC50:...
T63539 Glucocorticoid receptor-IN-2
Glucocorticoid receptor-IN-2 is a selective regulator of the glucocorticoid receptor (GR) and exhibits anti-inflammatory activity. IC50: 0.171 nM) and also has some transcriptional activating effect on MMTV (EC50: 0.94 n...
T75016 Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Mal
Glucocorticoid Receptor Agonist-1 Phosphate Ala-Ala-Mal functions as a glucocorticoid receptor agonist, utilized in the formulation of anti-CD40 antibody agent conjugates (ADC). It serves as a research tool for exploring...
T77835 Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Br
Glucocorticoid Receptor Agonist-1 Phosphate (Gly-Glu-Br) is an antibody-drug conjugate (ADC) linker utilized in the synthesis of ABBV-154, ABBV-927, ABBV-368, and related analogs [1].
T77869 Glucocorticoid receptor agonist-2 Ala-Ala-Mal
Glucocorticoid receptor agonist-2 Ala-Ala-Mal (compound 79) serves as a precursor for synthesizing anti-inflammatory antibody-drug conjugate (ADC) molecules and acts as an active reference for ABBV-3373 [1].
T74116 Glucocorticoid receptor agonist-1 Ala-Ala-Mal
Glucocorticoid receptor agonist-1 Ala-Ala-Mal (compound 88), a glucocorticosteroid and glucocorticoid receptor agonist, can be conjugated with Adalimumab to formulate an ADC [1].
T6635 EMD638683 SGK
EMD638683,a novel SGK inhibitor with antihypertensive potency(with an IC50 of 3 μM).
T82303 Glucocorticoid receptor agonist-1 phosphate Gly-Glu TFA
Glucocorticoid Receptor Agonist-1 Phosphate Gly-Glu (TFA) serves as a cleavable linker for the synthesis of Antibody-Drug Conjugates (ADCs).
T75130 Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Br
Glucocorticoid Receptor Agonist-1 Phosphate Ala-Ala-Br is a drug-linker conjugate for antibody-drug conjugates (ADCs), serving as a reaction reagent in the creation of anti-CD40 antibody agent conjugates [1].
T9977 SGK1-IN-4 SGK
SGK1-IN-4 is a selective inhibitor of SGK1 and can be used in studies about osteoarthritis.
T2622 GSK 650394 GSK650394 SGK , Influenza Virus
GSK 650394 is a serum- and glucocorticoid-regulated kinase-1 inhibitor.
T1560 Prednisolone Predonine,Hydroretrocortine,Metacortandralone Glucocorticoid Receptor , Endogenous Metabolite
Prednisolone (Hydroretrocortine) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.
T15451 GW-870086 Glucocorticoid Receptor
GW-870086 is an effective anti-inflammatory agent. GW-870086 also plays a role in a glucocorticoid receptor agonist (pIC50: 10.1 in A549 cells expressing NF-κB).
T14377 AZD5423 Glucocorticoid Receptor
AZD5423 is an inhaled, potent, selective, and non-steroidal modulator of glucocorticoid receptor (GR) and it effectively reduces allergen-induced responses in subjects with mild allergic asthma.
T8777 Beclometasone BecloMethasone Glucocorticoid Receptor
Beclometasone is a prototype glucocorticoid receptor agonist. It is used topically as an anti-inflammatory agent and in aerosol form for the treatment of asthma.
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