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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T37908 | Glucocorticoid receptor agonist-1 | Glucocorticoid Receptor | |
Glucocorticoid receptor agonist-1 is a potent glucocorticoid receptor agonist with an IC50 of 2.8 nM[1]. | |||
T67742 | EX-A5386 | Glucocorticoid receptor modulator-1 | Glucocorticoid Receptor |
EX-A5386 (Glucocorticoid receptor modulator-1) is a potent glucocorticoid receptor modulator, IC50/EC50<100nM. | |||
T11417 | Glucocorticoid receptor agonist | Others | |
Glucocorticoid receptor agonist is an effective glucocorticoid receptor agonist. | |||
T74697 | Glucocorticoid receptor agonist-2 | ||
Glucocorticoid receptor agonist-2 (compound 21), a glucocorticoid receptor agonist exhibiting an IC50 value of 6.6 nM, serves as an active reference for ABBV-3373 [1]. This compound is instrumental in the synthesis of an... | |||
T72102 | Glucocorticoid receptor modulator 1 | ||
Glucocorticoid receptor modulator 1 is a potent, orally active, non-steroidal selective glucocorticoid receptor modulator, exhibiting IC50 values of 9 nM and 130 nM against NF-κB and AP-1, respectively. It effectively re... | |||
T63551 | Glucocorticoid receptor-IN-1 | ||
Glucocorticoid receptor-IN-1 is a selective regulator of the glucocorticoid receptor (GR) and exhibits anti-inflammatory activity. glucocorticoid receptor-IN-1 has good transcriptional repression, acting on hMMP1 ( IC50:... | |||
T63539 | Glucocorticoid receptor-IN-2 | ||
Glucocorticoid receptor-IN-2 is a selective regulator of the glucocorticoid receptor (GR) and exhibits anti-inflammatory activity. IC50: 0.171 nM) and also has some transcriptional activating effect on MMTV (EC50: 0.94 n... | |||
T75016 | Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Mal | ||
Glucocorticoid Receptor Agonist-1 Phosphate Ala-Ala-Mal functions as a glucocorticoid receptor agonist, utilized in the formulation of anti-CD40 antibody agent conjugates (ADC). It serves as a research tool for exploring... | |||
T77835 | Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Br | ||
Glucocorticoid Receptor Agonist-1 Phosphate (Gly-Glu-Br) is an antibody-drug conjugate (ADC) linker utilized in the synthesis of ABBV-154, ABBV-927, ABBV-368, and related analogs [1]. | |||
T77869 | Glucocorticoid receptor agonist-2 Ala-Ala-Mal | ||
Glucocorticoid receptor agonist-2 Ala-Ala-Mal (compound 79) serves as a precursor for synthesizing anti-inflammatory antibody-drug conjugate (ADC) molecules and acts as an active reference for ABBV-3373 [1]. | |||
T74116 | Glucocorticoid receptor agonist-1 Ala-Ala-Mal | ||
Glucocorticoid receptor agonist-1 Ala-Ala-Mal (compound 88), a glucocorticosteroid and glucocorticoid receptor agonist, can be conjugated with Adalimumab to formulate an ADC [1]. | |||
T6635 | EMD638683 | SGK | |
EMD638683,a novel SGK inhibitor with antihypertensive potency(with an IC50 of 3 μM). | |||
T82303 | Glucocorticoid receptor agonist-1 phosphate Gly-Glu TFA | ||
Glucocorticoid Receptor Agonist-1 Phosphate Gly-Glu (TFA) serves as a cleavable linker for the synthesis of Antibody-Drug Conjugates (ADCs). | |||
T75130 | Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Br | ||
Glucocorticoid Receptor Agonist-1 Phosphate Ala-Ala-Br is a drug-linker conjugate for antibody-drug conjugates (ADCs), serving as a reaction reagent in the creation of anti-CD40 antibody agent conjugates [1]. | |||
T9977 | SGK1-IN-4 | SGK | |
SGK1-IN-4 is a selective inhibitor of SGK1 and can be used in studies about osteoarthritis. | |||
T2622 | GSK 650394 | GSK650394 | SGK , Influenza Virus |
GSK 650394 is a serum- and glucocorticoid-regulated kinase-1 inhibitor. | |||
T1560 | Prednisolone | Predonine,Hydroretrocortine,Metacortandralone | Glucocorticoid Receptor , Endogenous Metabolite |
Prednisolone (Hydroretrocortine) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. | |||
T15451 | GW-870086 | Glucocorticoid Receptor | |
GW-870086 is an effective anti-inflammatory agent. GW-870086 also plays a role in a glucocorticoid receptor agonist (pIC50: 10.1 in A549 cells expressing NF-κB). | |||
T14377 | AZD5423 | Glucocorticoid Receptor | |
AZD5423 is an inhaled, potent, selective, and non-steroidal modulator of glucocorticoid receptor (GR) and it effectively reduces allergen-induced responses in subjects with mild allergic asthma. | |||
T8777 | Beclometasone | BecloMethasone | Glucocorticoid Receptor |
Beclometasone is a prototype glucocorticoid receptor agonist. It is used topically as an anti-inflammatory agent and in aerosol form for the treatment of asthma. |