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AZD5423
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Purity:98.94%
AZD5423
Catalog No. T14377Cas No. 1034148-04-3
AZD5423 is an inhaled, potent, selective, and non-steroidal modulator of glucocorticoid receptor (GR) and it effectively reduces allergen-induced responses in subjects with mild allergic asthma.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $35 | In Stock | |
| 5 mg | $58 | In Stock | |
| 10 mg | $97 | In Stock | |
| 25 mg | $178 | In Stock | |
| 50 mg | $316 | In Stock | |
| 100 mg | Inquiry | In Stock | |
| 1 mL x 10 mM (in DMSO) | $58 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | AZD5423 is an inhaled, potent, selective, and non-steroidal modulator of glucocorticoid receptor (GR) and it effectively reduces allergen-induced responses in subjects with mild allergic asthma. |
| In vitro | The affinity of AZD5423 to the glucocorticoid receptor is high with an IC50 of 0.9 nM in a radioligand human glucocorticoid receptor assay. And it selectivity towards other steroid hormone receptors is >900-fold[1]. |
| Molecular Weight | 487.45 |
| Formula | C25H21F4N3O3 |
| Cas No. | 1034148-04-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 100 mg/mL (205.15 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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