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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T0328 | Hexetidine | NSC-17764 | Antibacterial , Antifungal |
Hexetidine (NSC-17764) is a bactericidal and fungicidal antiseptic. It is used as a 0.1% mouthwash for local infections and oral hygiene. | |||
T67915 | Succinate/succinate receptor antagonist 1 | Others | |
Succinate/succinate receptor antagonist 1 is a potent succinate receptor antagonist. Succinate/succinate receptor antagonist 1 interrupts succinate signals in gingival tissue and inhibits the activation of SucnRl Antagon... | |||
T68123 | Oxodipine | Calcium Channel | |
Oxodipine, a dihydropyridine-type calcium antagonist , inhibited KCl-induced aortic contraction in rabbits and reduced cardiac force in less potent rat ventricular test-paper contractions. In rat cultured neonatal ventri... | |||
T26838 | BLXA-4 | BLXA4,BLXA-4 ME,BLXA 4,BLXA-4-ME,BLXA4ME | |
BLXA-4 is used potentially to treat gingival diseases. | |||
T78549 | Ethylene glycol dimethacrylate | Reactive Oxygen Species | |
Ethylene glycol dimethacrylate, a methacrylate monomer, demonstrates cytotoxic and genotoxic impacts on human gingival fibroblasts (HGFs), elevating intracellular reactive oxygen species (ROS) levels, inducing DNA damage... | |||
TN2177 | Sanggenol L | c-Myc , NF-κB | |
Sanggenol L shows higher cytotoxicity against human oral tumor cell lines (HSC-2 and HSG) than against normal human gingival fibroblasts (HGF), it induces apoptosis via caspase activation and inhibition of NF-κB/IκBα± ph... | |||
T34811 | Terrein | NSC 291308,Terrain,(+)Terrein,NSC291308,NSC-291308 | |
Terrain, also known as NSC 291308, is a fungal metabolite with diverse biological activities. Terrein reduces age-related inflammation induced by oxidative stress through Nrf2/ERK1/2/HO-1 signalling in aged HDF cells. (+... | |||
T38309 | LL-37 amide (trifluoroacetate salt) | ||
LL-37 is a cationic and α-helical antimicrobial peptide expressed in human bone marrow, testis, granulocytes, and gingival epithelium and is upregulated in psoriatic lesions. It inhibits growth of Gram-positive E. coli D... |