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Terrein

Catalog No. T34811 CAS 582-46-7

Synonyms: NSC 291308, Terrain, (+)Terrein, NSC291308, NSC-291308

Terrain, also known as NSC 291308, is a fungal metabolite with diverse biological activities. Terrein reduces age-related inflammation induced by oxidative stress through Nrf2/ERK1/2/HO-1 signalling in aged HDF cells. (+)-terrein suppresses interleukin-6/soluble interleukin-6 receptor induced-secretion of vascular endothelial growth factor in human gingival fibroblasts.

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Terrein, CAS 582-46-7

Pack Size	Availability	Price/USD	Quantity
1 mg	35 days	$ 296.00
10 mg	35 days	$ 1,650.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	NSC 291308, Terrain, (+)Terrein, NSC291308, NSC-291308
Molecular Weight	154.16
Formula	C8H10O3
CAS No.	582-46-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Zaehle C, Gressler M, Shelest E, Geib E, Hertweck C, Brock M. Terrein biosynthesis in Aspergillus terreus and its impact on phytotoxicity. Chem Biol. 2014 Jun 19;21(6):719-31. doi: 10.1016/j.chembiol.2014.03.010. Epub 2014 May 8. PubMed PMID: 24816227. 2. Lee YH, Lee SJ, Jung JE, Kim JS, Lee NH, Yi HK. Terrein reduces age-related inflammation induced by oxidative stress through Nrf2/ERK1/2/HO-1 signalling in aged HDF cells. Cell Biochem Funct. 2015 Oct;33(7):479-86. doi: 10.1002/cbf.3145. Epub 2015 Sep 28. PubMed PMID: 26416516. 3. Mandai H, Omori K, Yamamoto D, Tsumura T, Murota K, Yamamoto S, Mitsudo K, Ibaragi S, Sasaki A, Maeda H, Takashiba S, Suga S. Synthetic (+)-terrein suppresses interleukin-6/soluble interleukin-6 receptor induced-secretion of vascular endothelial growth factor in human gingival fibroblasts. Bioorg Med Chem. 2014 Oct 1;22(19):5338-44. doi: 10.1016/j.bmc.2014.07.047. Epub 2014 Aug 7. PubMed PMID: 25151086. 4. Yin Y, Xu B, Li Z, Zhang B. Enhanced production of (+)-terrein in fed-batch cultivation of Aspergillus terreus strain PF26 with sodium citrate. World J Microbiol Biotechnol. 2013 Mar;29(3):441-6. doi: 10.1007/s11274-012-1196-x. Epub 2012 Oct 21. PubMed PMID: 23085955.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Terrein 582-46-7 NSC 291308 Terrain (+)Terrein NSC291308 NSC-291308 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.