co-factor — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2369	Rociletinib	AVL-301,CNX-419,CO-1686	EGFR
	Rociletinib (CNX-419) is an orally available small molecule, irreversible inhibitor of epidermal growth factor receptor (EGFR) with potential antineoplastic activity.		EGFR
T5692	Pyrroloquinoline quinone		Others , Endogenous Metabolite
	Pyrroloquinoline quinone (PQQ), as a well-known redox enzyme cofactor, PQQ can protect NS/PCs against glutamate toxicity associated with ROS-mediated mitochondrial pathway,		Others , Endogenous Metabolite
T5693	Pyrroloquinoline quinone disodium salt	Methoxatin disodium salt	Others , Endogenous Metabolite
	Pyrroloquinoline quinone disodium salt (Methoxatin disodium salt), an aromatic tricyclic o-quinone, is a redox cofactor for bacterial dehydrogenases. It is an efficient electron transfer catalyst from a number of organic...		Others , Endogenous Metabolite
T16486	Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD	PF-05231023	FGFR , PROTAC Linker
	Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD (PF-05231023) is a long-acting fibroblast growth factor 21 (FGF21) analog and is an FGF21-receptor agonist. It is also suitable for development as a potential treatment for T2DM.		FGFR , PROTAC Linker
T27307L	Fasnall HCl	Fasnall HCl（929978-58-5 Free base）	Fatty Acid Synthase
	Fasnall HCl is a selective FASN inhibitor that acts through its co-factor binding sites. Fasnall HCl also shows potent anti-tumor activity in the MMTV-Neu model of HER2(+) breast cancer, particularly when combined with c...		Fatty Acid Synthase
T27307	Fasnall		Fatty Acid Synthase
	Fasnall is a selective FASN inhibitor that acts through its co-factor binding sites. Fasnall shows potent anti-tumor activity in the MMTV-Neu model of HER2(+) breast cancer, particularly when combined with carboplatin.		Fatty Acid Synthase
T82866	Biotin-PEG-Biotin (MW 20000)
	Biotin-PEG-Biotin (MW 20000) is a bifunctional PEG derivative featuring biotin labels at each terminal end. As an enzyme co-factor, biotin facilitates protein labeling, while PEG, known for its hydrophilic nature and low...
T79741	CARM1 degrader-1		Histone Methyltransferase
	PROTAC CARM1 degrader-1 (compound 3b) serves as a highly potent degrader (DC50=8.1 nM) of the co-activator associated arginine methyltransferase (CARM1). This compound facilitates the degradation of CARM1 via the VHL-pro...		Histone Methyltransferase
T35538	HPI-1 (hydrate)	HPI-1 hydrate
	HPI-1 (hydrate) is a Hedgehog (Hh) pathway inhibitor that suppresses signaling through Sonic Hh (IC50= 1.5 μM) without significantly affecting Wnt signaling (IC50≥ 30 μM).1HPI-1 suppresses Hh activation induced by loss o...
T79742	CARM1 degrader-2		Histone Methyltransferase
	PROTAC CARM1 degrader-2 (compound 3e), with a DC50 value of 8.8 nM, is a VHL- and proteasome-dependent degrader of co-activator associated argininemethyltransferase (CARM1). It not only promotes the degradation of CARM1 ...		Histone Methyltransferase
T36064	N-Oleoyl Glutamine
	N-Oleoyl glutamine is an endogenous N-acyl amine.1,2It is both formed and degraded by peptidase M20 domain-containing 1 (PM20D1), a factor secreted by thermogenic adipose cells. N-Oleoyl glutamine (50 μM) induces mitocho...
T74564	Phospholipid-PEG-Biotin (MW 2000)
	Phospholipid-PEG-Biotin (MW 2000), a biotin-labeled phospholipid PEG derivative, is designed for modifying the surfaces of liposomes, cells, and pancreatic islets intended for cell transplantation. This compound integrat...
T74566	Phospholipid-PEG-Biotin (MW 5000)
	Phospholipid-PEG-Biotin (MW 5000), a derivative of phospholipid PEG, serves to modify the surfaces of liposomes, cells, and pancreatic islets for cell transplantation. This compound incorporates a phospholipid (a lipid f...
T82873	Biotin-PEG-Alk (MW 10000)
	Biotin-PEG-Alk (MW 10000) is a biotinylated polyethylene glycol (PEG) derivative featuring an alkyne group for click chemistry applications. This compound combines biotin, an enzyme co-factor used in protein labeling, wi...
T82874	Biotin-PEG-Alk (MW 1000)
	Biotin-PEG-Alk (MW 1000) is a biotinylated polyethylene glycol (PEG) derivative with alkyne functionality for click chemistry applications. Biotin serves as an enzyme co-factor suitable for protein labeling, while PEG pr...
T82867	Biotin-PEG-azide (MW 3400)
	Biotin-PEG-azide (MW 3400) is a biotinylated polyethylene glycol (PEG) derivative featuring an azide group. Biotin serves as an enzyme co-factor suitable for protein labeling, while PEG is a hydrophilic, water-soluble, l...
T35814	Urocortin III (human) (trifluoroacetate salt)
	Urocortin III is a neuropeptide hormone and member of the corticotropin-releasing factor (CRF) family which includes mammalian CRF , urocortin , urocortin II , frog sauvagine, and piscine urotensin I.1 Human urocortin II...