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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T26357 | Pitstop 2 | Apoptosis | |
Pitstop2 is a selective inhibitor of amphiphysin association of clathrin terminal domain with an IC50 value of 12 μM. Pitstop2 acutely interferes with receptor-mediated endocytosis, entry of HIV, and synaptic vesicle rec... | |||
T9063 | Clathrin-IN-1 | HIV Protease | |
Clathrin-IN-1 is a inhibitor of clathrin, and inhibits clathrin-mediated endocytosis (CME) by associating with the terminal domain of clathrin. It has the potential for anti-cancer research. | |||
T64369 | Dynamin IN-2 | Dynamin | |
Dynamin IN-2 (compound 43) is a Wiskostatin analogue. Dynamin IN-2 is a potent dynamin inhibitor (dynamin I GTPase, IC50= 1.0 μM). Dynamin IN-2 blocks clathrin mediated endocytosis (CME) (IC50= 9.5 μM). | |||
T64368 | ES9-17 | Others | |
ES9-17, an analog of ES9 (endosidin9), is an inhibitor of clathrin-mediated endocytosis (CME). ES9-17 inhibits the uptake of FM4-64 and transferrin. ES9-17 inhibits root growth of Arabidopsis seedings. | |||
T15556 | Ikarugamycin | Others | |
Ikarugamycin, an antibiotic, is an inhibitor of clathrin-mediated endocytosis (CME). | |||
T72894 | Clathrin-IN-2 | ||
Clathrin-IN-2 is a potent inhibitor of clathrin-mediated endocytosis (CME), demonstrating an IC50 value of 2.3 μM. Additionally, it exhibits inhibitory effects on dynamin I GTPase, with an IC50 of 7.7 μM. | |||
T61488 | Dynole 2-24 | ||
Dynole 2 24 is an indole-based dynamin GTPase inhibitor ( IC 50 =0.56 μM for dynamin I). Dynole 2 24 is nontoxic and shows increased potency against dynamin I and II in vitro and in cells (IC (CME) =1.9 μM). Dynole 2 2... | |||
T36368 | 2H-Cho-Arg (trifluoroacetate salt) | ||
2H-Cho-Arg is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection. It forms a complex with plasmid DNA (pDNA) and dec... | |||
T83891 | Sulfonadyn-47 | ||
Sulfonadyn-47 is a dynamin inhibitor that effectively inhibits dynamin GTPase activity with an IC50 of 3.5 µM in cell-free assays. Additionally, it disrupts clathrin-mediated endocytosis in U2OS cells (IC50 = 27.3 µM) an... |