6
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T21876 | DC_AC50 | Apoptosis , Others | |
DC_AC50 is a dual inhibitor of Atox1 and CCS (copper chaperones). Inhibiting intracellular copper chaperones as a means of reducing/preventing acquired chemotherapy resistance.DC_AC50 binding to Atox1 and CCS and reducin... | |||
T3594 | ML346 | HSP | |
ML346 is a novel activator of Hsp70. | |||
T5152 | MKT-077 | MKT 077,FJ-776,MKT077 | HSP |
MKT-077 (FJ-776) is a cationic rhodacyanine dye that demonstrates antiproliferative activity against cancer cell lines (EC50s: 1.4-2.2 μM in vitro) through its ability to inhibit members of the Hsp70 family of molecular ... | |||
T62105 | NT219 | NT-219 | STAT |
NT219 is a dual inhibitor of insulin receptor substrate 1/2 (IRS1/2) and STAT3, enhances the aggregation of misfolded prion protein NT219 affects the levels of certain molecular chaperones and inhibits STAT3 phosphorylat... | |||
T71552 | ASC-JM-17 | ||
ASC-JM-17 is an activator of both Nrf1 and Nrf2 proteins. ASC-JM17 acts on Nrf1, Nrf2 and Hsf1 to increase the expression of proteasome subunits, antioxidant enzymes and molecular chaperones. ASC-JM17 ameliorates toxicit... | |||
T82171 | HS-291 | ROS Kinase | |
HS-291 is a HtpG inhibitor targeting Borrelia burgdorferi (Bb), composed of BX-2819 (high affinity for Bb HtpG), a PEG linker, and Verteporfin (a photoactive toxin). Upon light activation, HS-291 generates reactive oxyge... |