acyl-coenzyme — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T10857	Coenzyme A		Endogenous Metabolite
	Coenzyme A is an obligatory cofactor in all living cells synthesized from pantothenate (Vitamin B5), adenosine triphosphate (ATP), and cysteine.		Endogenous Metabolite
T76124	Acyl coenzyme A synthetase
	Acyl coenzyme A synthetase (ACS), also known as acetyl coenzyme A synthetase, plays a pivotal role in biochemical research. This enzyme catalyzes the activation of fatty acids via coenzyme A through a two-step thioesteri...
T12225L	Nevanimibe hydrochloride	PD-132301 hydrochloride,ATR101 hydrochloride	Apoptosis , Acyltransferase
	Nevanimibe hydrochloride (PD-132301 hydrochloride) is an orally active and selective inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) (EC50 of 9 nM).		Apoptosis , Acyltransferase
T30961	CL 277082	CL277082,CL-277082,Ddpmhu	Others
	CL 277082 (Ddpmhu) is an acyl coenzyme A:cholesterol O-acyltransferase inhibitor that inhibits granuloma tissue ACAT activity.		Others
T23550	YM-750	YM 750	Acyltransferase
	YM-750 is a potent inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), with an IC50 value of 0.18 μM. ACAT is an enzyme that catalyzes the conversion of cholesterol and long-chain fatty-acyl-coenzyme A into cholest...		Acyltransferase
T8314	RP-64477	RP64477	Acyltransferase
	RP-64477 is the cholesterol esterifying enzyme Acyl-coenzyme A:cholesterol O-acyltransferase (ACAT) inhibitor.		Acyltransferase
T25651	Lecimibide	DuP128,DuP-128,DuP 128	Acyltransferase
	Lecimibide (DuP 128) is a potent and selective inhibitor of acyl coenzyme A: cholesterol acyltransferase (ACAT), which can be used to study diseases due to high lipids.		Acyltransferase
T27245L	Eflucimibe	L0081,F-12511	Acyltransferase
	Eflucimibe (L0081) is an acyl coenzyme A: cholesterol acyltransferase inhibitor for the treatment of cardiovascular disease and endocrine and metabolic disorders, and can be used to study atherosclerosis and hyperlipidem...		Acyltransferase
T2753	Avasimibe	PD-148515,CI-1011	P450 , Acyltransferase
	Avasimibe (PD-148515) is an orally bioavailable inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT, IC50: 3.3 μM) that prevents cholesterol deposition in the arterial wall. It also inhibits human P450 isoenz...		P450 , Acyltransferase
T4867	Erucic acid	Prifac 2990,13(Z)-Docosenoic Acid,cis-13-docosenoic acid	PI3K , Endogenous Metabolite
	Increased levels of erucic acid (22:1n9) have been found in the red blood cell membranes of autistic subjects with developmental regression (PMID: 16581239 ). Erucic acid (13(Z)-Docosenoic Acid) is broken down long-chain...		PI3K , Endogenous Metabolite
T32768	Linoleoyl-coenzyme A	Coenzyme A,linoleoyl-
	Linoleoyl-coenzyme A is a substrate used to investigate the specificity and kinetics of acyl-CoA.
T40553	ACAT-IN-6
	ACAT-IN-6, an acyl-Coenzyme A: cholesterol acyltransferase (ACAT) inhibitor, displays potent inhibition of NF-κB mediated transcription.
T70300	Avasimibe sodium
	Avasimibe sodium is an acyl coenzyme A: cholesterol acyltransferase (ACAT) inhibitor.
T74043	Hexanoyl coenzyme A trilithium
	Hexanoyl coenzyme A trilithium, a medium-chain fatty acyl coenzyme A derivative found universally in organisms, serves as a precursor for cannabinoid biosynthesis and functions as a competitive inhibitor of medium-chain ...
T39417	ACAT-IN-2
	ACAT-IN-2 is a potent inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT). This compound effectively blocks NF-κB mediated transcription.
T39415	ACAT-IN-9
	ACAT-IN-9, acts as an inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT). By doing so, it effectively suppresses NF-κB mediated transcription.
T12225	Nevanimibe	ATR-101,PD-132301	Others
	Nevanimibe is an orally active and selective inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) (EC50 of 9 nM).		Others
T64276	Octanoyl coenzyme A lithium
	Octanoyl coenzyme A lithium is a derivative of the fatty acid acyl coenzyme A. Octanoyl coenzyme A lithium inhibits citrate synthase and glutamate dehydrogenase (IC50: 0.4-1.6 mM).
T39414	ACAT-IN-7
	ACAT-IN-7 is a compound that acts as an inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT) enzyme. It effectively suppresses the transcription process mediated by NF-κB.
T32598	Lauroyl-coenzyme A	Dodecanoyl-coa,Coenzyme A, lauroyl-,Lauroyl-coa
	Lauroyl-coenzyme A can function as an acyl group carrier, acetyl-CoA. It can be used as an intermediate in lipid metabolism and is involved in lipid biosynthesis and fatty acid transport.