zikv — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T63131	ZIKV-IN-1
	ZIKV-IN-1 is a potent inhibitor of zika virus (EC50: 2.8 μM, EC90: 6.8 μM). zIKV-IN-1 has anti-ZIKV effects and low cytotoxicity. zIKV-IN-1 shows high affinity for the RdRp domain of ZIKV.
T64123	ZIKV-IN-5
	ZIKV-IN-5 is an acid-stable, low cytotoxic anti-ZIKV agent with an EC50 value of 0.71 μM. ZIKV-IN-5 showed effective inhibition of ZIKV NS5 MTase activity.
T63533	ZIKV-IN-4
	ZIKV-IN-4 is a low cytotoxic, acid-stable anti-ZIKV agent with an EC50 value of 3.49 μM. ZIKV-IN-4 exhibited potent inhibition of ZIKV NS5 MTase.
T64067	ZIKV-IN-2
	ZIKV-IN-2 is a potent inhibitor of ZIKV NS5 methyltransferase (MTase) (IC50: 38.86 μM) and inhibits the replication and infection of ZIKV, which can be used to study Zika virus (ZIKV).
T73292	ZIKV-IN-3
	ZIKV-IN-3, a derivative of andrographolide, serves as a potent inhibitor of the Zika virus (ZIKV) NS5 methyl transferase (MTase), showcasing an IC50 of 18.34 μM. It effectively curtails ZIKV replication and infection, ma...
T69868	ZIKV-IN-K22
	ZIKV-IN-K22 is a potent antiviral agent against a broad range of coronaviruses by targeting membrane-bound viral RNA replication, effectively inhibiting ZIKV with IC50 of 2.1 μM.
T80729	ZIKV-IN-6
	ZIKV-IN-6 (compound 22) acts as a direct inhibitor of the Zika virus (ZIKV) by binding to its RNA-dependent RNA polymerase (RdRp) and obstructing viral RNA synthesis mediated by the ZIKV NS5 protein. This compound also d...
T7785	T-1105		Influenza Virus
	T-1105 is a broad-spectrum antiviral inhibitor.		Influenza Virus
T5429	Theaflavin 3,3'-digallate	8-Gingerol,TFDG	Virus Protease , Antioxidant , HIV Protease , HSV
	Theaflavin 3,3'-digallate (8-Gingerol) , a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory and cancer chemopreventive actions, it reduces tumor angiogenesis by downregul...		Virus Protease , Antioxidant , HIV Protease , HSV
T23004	ML-SA1	Mucolipin synthetic agonist 1	Others , TRP/TRPV Channel
	ML-SA1 (Mucolipin synthetic agonist 1) is a selective TRPML agonist, inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity. The IC50 value of ML-SA1 against DENV...		Others , TRP/TRPV Channel
T72051	LabMol-319		Virus Protease
	LabMol-319 is a potent Zika virus (ZIKV) NS5 RdRp inhibitor with antiviral activity for the study of ZIKV virus.		Virus Protease
T3S1852	Cephaeline hydrochloride		Others , Virus Protease , Influenza Virus
	Cephaeline hydrochloride, a phenolic alkaloid found in Indian Ipecac, effectively inhibits the infection of viruses ZIKV and EBOV.		Others , Virus Protease , Influenza Virus
T0265	Merbromin	Mercury dibromofluorescein disodium salt	Others , Antibacterial
	Merbromin (Mercury dibromofluorescein disodium salt) is an organomercuric disodium salt compound and a fluorescein, used as a topical antiseptic for minor cuts and scrapes.		Others , Antibacterial
T12941	SN 2		TRP/TRPV Channel
	SN 2 is a novel and potent TRPML3 ion channel activator(EC50 of 1.8±0.13 μM).		TRP/TRPV Channel
T62104	NS2B/NS3-IN-5
	NS2B/NS3-IN-5 (Compound 25b) is a variant of the DENV2 and ZIKV NS2B/NS3 protease inhibitor with IC50 values of 0.67 μM and 4.38 μM for the NS2B/NS3 protease of ZIKV and DENV2, respectively.
T69942	CN-716 HCl
	cn-716 is a novel Zika virus (ZIKV) NS2B-NS3pro protease inhibitor.
T62437	NS2B/NS3-IN-6
	NS2B/NS3-IN-6 (Compound 1a) is a variant of the DENV and ZIKV NS2B/NS3 protease inhibitor with IC50 values of 2.23 μM and 25.2 μM for the NS2B/NS3 protease of ZIKV and DENV, respectively.
T60458	NS2B/NS3-IN-4
	Compound 34e (NS2B/NS3-IN-4) is an allosteric inhibitor of the DENV2 and ZIKV NS2B/NS3 proteases, exhibiting IC50 values of 0.69 µM for DENV2 and 1.04 µM for ZIKV NS2B/NS3 proteases [1].
T79334	Antiviral agent 36		DNA/RNA Synthesis
	Antiviral agent 36 (compound 27), a potent inhibitor of both dengue (DENV) and Zika (ZIKV) viruses, demonstrates replication inhibition with EC50 values of 100 nM for ZIKV-FLR, 90 nM for ZIKV-HN16, 210 nM for DENV-2, and...		DNA/RNA Synthesis
T80003	Wulfenioidin H
	Wulfenioidin H (Compound 5), a diterpenoid, demonstrates anti-Zika virus (ZIKV) activity by inhibiting the expression of the ZIKV envelope (E) protein, resulting in an effective concentration \( EC_{50} \) value of 8.50 ...