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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T38111 | Dimethyl-W84 (dibromide) | Dimethyl-W84 (dibromide) | |
Dimethyl-W84 is a selective allosteric modulator of the M2 muscarinic acetylcholine receptor. It hinders the dissociation of the orthosteric antagonist N-methylscopolamine from the M2 receptor with an EC50 value of 3 nM. | |||
T23524 | W-84 dibromide | HDMPPA | AChR |
W-84 dibromide (HDMPPA) is a M2-receptor selective modulator. | |||
T6527 | GW842166X | Cannabinoid Receptor | |
GW842166X is a potent and highly selective agonist of cannabinoid receptor CB2 receptor with EC50 of 63 nM, shows no significant activity at CB1 receptor. Phase 2. | |||
T15454 | GW843682X | GW843682 | VEGFR , PLK , CDK , PDGFR , Aurora Kinase |
GW843682X (GW843682) is a selective and ATP-competitive inhibitor of PLK1 and PLK3 (IC50s = 2.2 nM and 9.1 nM). | |||
T27516 | GW844520 | ||
GW844520 is a potent and selective inhibitor of the cytochrome bc1 complex of mitochondrial electron transport in P. falciparum. | |||
T36574 | GW841819X | GW841819X | |
GW841819X is an analogue of (+)-JQ1 and a novel inhibitor of BET bromodomains. GW841819X was a single enantiomer but of undefined chirality at the 4-position of the benzodiazepine ring3. GW841819X and JQ1 were recently d... | |||
T69571 | SEW84 | ||
SEW84 is an inhibitor of Aha1-stimulated Hsp90(ASH) ATPase activity.SEW84 inhibits Aha1-stimulated Hsp90(ASH) activity with an IC50 value of 0.3 μM.SEW84 can be used in the study of protein deposition diseases. | |||
T27517 | GW848687X | GW-848687X,GW 848687X | |
GW848687X, a potent and selective prostaglandin EP1 receptor antagonist, is used for the treatment of inflammatory pain. |