Search Result

Search Results for " vitronectin "

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T80859	Vitronectin
	Vitronectin, a multifunctional glycoprotein found in blood and the extracellular matrix, interacts with glycosaminoglycans, collagen, plasminogen, and the urokinase-receptor, in addition to stabilizing the inhibitory con...
T38603	Vitronectin (367-378)
	Vitronectin (367-378) is a peptide derived from residues 367-378 of the multifunctional glycoprotein known as Vitronectin. Vitronectin plays a pivotal role in cell growth, angiogenesis, and metastasis within various huma...
T2494	Cilengitide	EMD 121974	Integrin , Autophagy
	Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.		Integrin , Autophagy
TP1879L1	P11 acetate		Integrin
	P11 acetate is an integrin αvβ3-vitronectin interaction antagonist(IC50 = 2.74 nM).		Integrin
T76844	Abciximab	C7E3	Integrin
	Abciximab (C7E3) is a mouse/human chimeric monoclonal antibody that is a potent glycoprotein IIb/IIIa inhibitor. Abciximab has anti-platelet aggregation and leukocyte adhesion, acting by binding to glycoproteins IIb/IIIa...		Integrin
TP1736L	Fibrinogen-Binding Peptide 137235-80-4(fb-acetate)		Others
	Fibrinogen-Binding Peptide (designed by anticomplementarity hypothesis) is a presumptive peptide mimic of the vitronectin binding site on the fibrinogen receptor. Fibrinogen-Binding Peptide binds fibrinogen and inhibits ...		Others
T24796	SK&F 107260	Skf107260,Skf-107260,Skf 107260
	SK&F 107260 is an RGD-containing peptide. It is a potent GP IIb/IIIa antagonist and a vitronectin antagonist.
TP1879	HSDVHK-NH2	P11
	Potent antagonist of the integrin αvβ3-vitronectin interaction (IC50 = 25.72 nM). Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic.
TP1736	Fibrinogen-Binding Peptide
	Fibrinogen-Binding Peptide (designed by anticomplementarity hypothesis) is a presumptive peptide mimic of the vitronectin binding site on the fibrinogen receptor. Fibrinogen, a soluble plasma protein, is a cofactor in pl...
T75835	HSDVHK-NH2 TFA
	HSDVHK-NH2 TFA acts as an antagonist to the αvβ3-vitronectin integrin interaction, displaying an inhibitory concentration (IC 50) of 1.74 pg/mL (2.414 pM) [1] [2].
T82919	Batifiban TFA
	Batifiban TFA, a cyclic peptide and antagonist of the platelet glycoprotein GPⅡb/Ⅲa, inhibits platelet aggregation by blocking the binding of circulating vitronectin to integrin ανβ3 [1].
T38363	MeOSuc-AAPV-pNA
	Proteinase 3 (PR3, myeloblastin) is a polymorphonuclear leukocyte serine proteinase that degrades matrix proteins including fibronectin, laminin, vitronectin, and collagen type IV to generate antimicrobial peptides. Neut...
T83848	VnP-16 TFA
	VnP-16, a synthetic peptide fragment mirroring amino acids 270-281 of vitronectin (a multifunctional glycoprotein involved in cell attachment, migration, and spreading), promotes attachment and spreading of isolated huma...
T83736	RTDLDSLRTYTL TFA
	RTDLDSLRTYTL is a ligand for αVβ6 integrin, exhibiting selective inhibition of fibronectin's binding to αVβ6 integrin with considerably less effect on the interactions between vitronectin and αVβ3 or αVβ5, as well as fib...
T70368	SF0166
	SF0166 is a potent, selective antagonist of α v β 3, demonstrating IC 50 values of 0.6 nM for α v β 3, 8 nM for α v β 6, and 13 nM for α v β 8. It effectively inhibits cellular adhesion to vitronectin in human, rat, rabb...

Compounds

Vitronectin (367-378)

Target: Integrin, Autophagy

Fibrinogen-Binding Peptide 137235-80-4(fb-acetate)

Synonym: Skf107260,Skf-107260,Skf 107260

Fibrinogen-Binding Peptide

Cat No.	Product Name	Targets
T14347	Aureothricin	Antibacterial
	Aureothricin, a dithiolopyrrolone (DTP) antibiotic originally derived from Streptomyces, demonstrates a broad-spectrum of antibacterial effectiveness. Additionally, it inhibits the adhesion of human umbilical vein endoth...	Antibacterial
TN5221	(-)-Variabilin
	Variabilin, a novel inhibitor of human platelet aggregation, it is a potent RGD (Arg-Gly-Asp)-containing antagonist of the fibrinogen receptor glycoprotein IIb-IIIa (GPIIb-IIIa; αIIbβ3) and the vitronectin receptor αvβ3....

Natural Products

Aureothricin

T14347

Synonym:

Target: Antibacterial

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-00121	Vitronectin Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Vitronectin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 53.7 kDa and the accession number is D9ZGG2.
TMPY-01861	Vitronectin Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Vitronectin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.2 kDa and the accession number is P29788.
TMPJ-00472	Vitronectin Protein, Human, Recombinant (Truncated, His)	Human	HEK293 Cells
	Vitronectin, also known as VTN, is a large glycoprotein found in blood and the extracellular matrix (ECM). Vitronectin is a plasma glycoprotein implicated as a regulator of diverse physiological process, including blood ...
TMPY-05716	Integrin alpha V beta 3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Integrin alpha-V & beta-3 (ITGAV/ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor.
TMPY-05717	Integrin alpha V beta 8 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Integrin alpha V beta 8 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. ITGAVB8 does not appear to assume different activation states; and the cytoplasmic tail does not connect to the cyto...
TMPH-03598	Streptopain Protein, S. pyogenes serotype M28, Recombinant (His & SUMO)	Streptococcus pyogenes	E. coli
	Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelia...
TMPH-03599	Streptopain Protein, S. pyogenes, Recombinant (His & SUMO)	Streptococcus pyogenes	E. coli
	Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelia...
TMPY-02759	Kallikrein 6/KLK6 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	KLK6 (kallikrein-related peptidase 6), also known as Klk7, belongs to the peptidase S1 family, Kallikrein subfamily. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence...