vhl ligand 6 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T17924	(S,R,S)-AHPC-PEG2-NH2 hydrochloride	VH032-PEG2-NH2 hydrochloride,VHL Ligand-Linker Conjugates 3 hydrochloride,E3 ligase Ligand-Linker Conjugates 6	Others , E3 Ligase Ligand-Linker Conjugate
	(S,R,S)-AHPC-PEG2-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 6) is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-PEG2-NH2 hydrochloride incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit...		Others , E3 Ligase Ligand-Linker Conjugate
T17925	(S,R,S)-AHPC-PEG2-NH2	VH032-PEG2-NH2,VHL Ligand-Linker Conjugates 3,E3 ligase Ligand-Linker Conjugates 6 Free Base	Others , E3 Ligase Ligand-Linker Conjugate
	(S,R,S)-AHPC-PEG2-NH2 (VHL Ligand-Linker Conjugates 3) is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-PEG2-NH2 incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis ...		Others , E3 Ligase Ligand-Linker Conjugate
T18600	VH032 thiol	VHL ligand 6	Others
	VH032 thiol (VHL ligand 6) is a VHL ligand that interacts with pan-BET inhibitor JQ1 through a linker to create a PROTAC[1] compound.		Others
T13671L	(S,R,S)-AHPC-Me dihydrochloride	VHL ligand 2 dihydrochloride,E3 ligase Ligand 1 dihydrochloride,(S,R,S)-AHPC-Me dihydrochloride (1948273-02-6 free base)	Others
	(S,R,S)-AHPC-Me dihydrochloride, also known as VHL ligand 2 dihydrochloride, is a chemical compound utilized in the synthesis of ARV-771. ARV-771, a BET PROTAC degrader relying on von Hippel-Landau (VHL) E3 ligase, demon...		Others
T17913	(S,R,S)-AHPC-PEG2-N3	VHL Ligand-Linker Conjugates 6,VH032-PEG2-N3,E3 ligase Ligand-Linker Conjugates 13	Others , Ligand for E3 Ligase
	(S,R,S)-AHPC-PEG2-N3 (VHL Ligand-Linker Conjugates 6) is a synthesized E3 ligase ligand-linker conjugate containing a (S,R,S)-AHPC based VHL ligand and 2 unit PEG linker.		Others , Ligand for E3 Ligase
T17911	(S,R,S)-AHPC-C6-PEG3-C4-Cl	VH032-C6-PEG3-C4-Cl,VHL Ligand-Linker Conjugates 12,E3 ligase Ligand-Linker Conjugates 8	Others
	(S,R,S)-AHPC-C6-PEG3-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker. (S,R,S)-AHPC-C6-PEG3-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in ce...		Others
T17926	(S,R,S)-AHPC-PEG6-C4-Cl	VHL Ligand-Linker Conjugates 10,E3 ligase Ligand-Linker Conjugates 9,VH032-PEG6-C4-Cl	Others
	(S,R,S)-AHPC-PEG6-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 6-unit PEG linker. (S,R,S)-AHPC-PEG6-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-bas...		Others
T17350	ACBI1		Apoptosis , Epigenetic Reader Domain , PROTACs
	ACBI1 is a potent PROTAC degrader of BAF ATPase subunits SMARCA2 and SMARCA4, also degrades the polybromo-associated BAF (PBAF) complex member PBRM1, with DC50s of 6 nM, 11 nM and 32 nM for SMARCA2, SMARCA4 and PBRM1 in ...		Apoptosis , Epigenetic Reader Domain , PROTACs
T18059	K-Ras ligand-Linker Conjugate 6		Others
	K-Ras ligand-Linker Conjugate 6 is a chemical compound that combines a ligand for K-Ras recruiting moiety and a PROTAC linker. This compound can recruit E3 ligases, including VHL, CRBN, MDM2, and IAP. K-Ras ligand-Linker...		Others
T36246	SJF 8240
	c-MET degrader. Comprises MET inhibitor foretinib (GSK 1363089; Cat. No. 6056) joined by a linker to a von Hippel-Lindau (VHL) recruiting ligand. Degrades c-MET within 6 hours in vitro. Inhibits agonist-driven AKT phosph...
T83947	HDAC4 CHDI Degrader 11
	HDAC4 CHDI Degrader 11 is a potent, selective degrader of HDAC4 (PROTAC) with DC_50 values of 4 nM and 6 nM in Jurkat E6-1 and Jurkat cells, respectively. This compound integrates the class IIa HDAC inhibitor trifluorome...