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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN5100 | Taspine | ERK , EGFR , BCL , VEGFR , MAPK , Akt | |
Taspine shows antitumor activity by modulating the EGFR signaling pathway of Erk1/2 and Akt in vitro and in vivo, it can inhibit growth and induce apoptosis of HUVEC in a dose-dependent manner, it has shown meaningful an... | |||
T28960 | Thaspine HCl | Thaspine,Thaspine HCl, NSC 135784,NSC-135784,NSC135784 | |
Thaspine is a potent topoisomerase IB inhibitor. Taspine downregulates VEGF expression and inhibits proliferation of vascular endothelial cells through PI3 kinase and MAP kinase signaling pathways. |