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Taspine

Catalog No. TN5100 CAS 602-07-3

Taspine shows antitumor activity by modulating the EGFR signaling pathway of Erk1/2 and Akt in vitro and in vivo, it can inhibit growth and induce apoptosis of HUVEC in a dose-dependent manner, it has shown meaningful angiogenesis activity. Taspine exhibits a dose-related cicatrizant effect and an ED50 of 0.375 mg/kg.

Taspine, CAS 602-07-3

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Biological Description

Chemical Properties

Storage & Solubility Information

Description	Taspine shows antitumor activity by modulating the EGFR signaling pathway of Erk1/2 and Akt in vitro and in vivo, it can inhibit growth and induce apoptosis of HUVEC in a dose-dependent manner, it has shown meaningful angiogenesis activity. Taspine exhibits a dose-related cicatrizant effect and an ED50 of 0.375 mg/kg.
Targets&IC50	Akt , Bcl-2 , EGFR , ERK , MAPK , VEGFR

Molecular Weight	369.37
Formula	C20H19NO6
CAS No.	602-07-3

Storage

0-4℃ for short term (days to weeks), or -20℃ for long term (months).

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Related Products

Related compounds with same targets

Karanjin Myristicin Vatalanib free base EGFR-IN-7 A-674563 2HCl(552325-73-2(fb-2hcl)) UNC0064-12 hydrochloride (1430089-64-7(free base)) Cetuximab (anti-EGFR) Bevacizumab

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Answers to questions you may have can be found in the Inhibitor Handling Instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.