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Search Results for " trpa1 in 1 "

9

Compounds

Cat No. Product Name Synonyms Targets
T39935 TRPA1-IN-1 TRPA1-IN-1 Others
TRPA1-IN-1 is a potent, selective antagonist of the TRPA1 channel, demonstrating significant oral bioavailability as a small molecule.
T29968 AMG-0347 UNII-CD7L9290QR TRP/TRPV Channel
AMG-0347 (UNII-CD7L9290QR) is a small molecule inhibitor targeting TRPA1(transient receptor potential ankyrin 1) ion channels, a receptor found in sensory neurons and involved in the detection of pain and environmental s...
TN3575 (±)-Cannabichromene Cannabichromene,Cannabichrome Cannabinoid Receptor
(±)-Cannabichromene is a major non-psychotropic phytocannabinoid that inhibits endocannabinoid inactivation and activates the transient receptor potential ankyrin-1 (TRPA1), it selectively reduces inflammation-induced hy...
T78082 Supercinnamaldehyde NF-κB , Antibacterial , TRP/TRPV Channel
Supercinnamaldehyde is a transient receptor potential anchor protein 1 (TRPA1) activator with thousands of anticancer and antimicrobial activities.Supercinnamaldehyde inhibits NF-κB signaling, induces cytoprotective resp...
T16532 Pico145 HC-608 TRP/TRPV Channel
Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels. Pico145 inhibits ( )-englerin A-activated TRPC4/TRPC5 channels (IC50s: 0.349 and 1.3 nM in cells) It also shows no effect on TRPC3, TRPC6, TRPV1, TRPV4, T...
TCS0102 Pulegone (+)-Pulegone Calcium Channel , Endogenous Metabolite , TRP/TRPV Channel
1. Pulegone ((+)-Pulegone) has cytotoxicity followed by regenerative cell proliferation is the MOA for Pulegone-induced urothelial tumors in female rats. 2. Pulegone induces a verapamil-sensitive psychostimulant effect t...
T80843 Wasabi Receptor Toxin WaTx
Wasabi Receptor Toxin (WaTx) activates TRPA1 through prolonged channel openings while reducing Ca2+ permeability. This compound has potential applications in studying both acute and persistent pain [1].
T38372 2-Fluoro-4-iodo benzonitrile Others
2-Fluoro-4-iodo benzonitrile is a building block.1,2It has been used in the synthesis ofL. infantumtrypanothione reductase (Li-TryR) dimerization and oxidoreductase activity inhibitors.12-Fluoro-4-iodo benzonitrile has a...
T31995 GRC-17536 GRC17536,GRC 17536 Others
GRC-17536 is an orally available, potent, and selective transient receptor potential anchor protein 1 (TRPA1) inhibitor that has been shown to be highly effective in the treatment of inflammation and neuropathic pain in ...
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