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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T39935 | TRPA1-IN-1 | TRPA1-IN-1 | Others |
TRPA1-IN-1 is a potent, selective antagonist of the TRPA1 channel, demonstrating significant oral bioavailability as a small molecule. | |||
T29968 | AMG-0347 | UNII-CD7L9290QR | TRP/TRPV Channel |
AMG-0347 (UNII-CD7L9290QR) is a small molecule inhibitor targeting TRPA1(transient receptor potential ankyrin 1) ion channels, a receptor found in sensory neurons and involved in the detection of pain and environmental s... | |||
TN3575 | (±)-Cannabichromene | Cannabichromene,Cannabichrome | Cannabinoid Receptor |
(±)-Cannabichromene is a major non-psychotropic phytocannabinoid that inhibits endocannabinoid inactivation and activates the transient receptor potential ankyrin-1 (TRPA1), it selectively reduces inflammation-induced hy... | |||
T78082 | Supercinnamaldehyde | NF-κB , Antibacterial , TRP/TRPV Channel | |
Supercinnamaldehyde is a transient receptor potential anchor protein 1 (TRPA1) activator with thousands of anticancer and antimicrobial activities.Supercinnamaldehyde inhibits NF-κB signaling, induces cytoprotective resp... | |||
T16532 | Pico145 | HC-608 | TRP/TRPV Channel |
Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels. Pico145 inhibits ( )-englerin A-activated TRPC4/TRPC5 channels (IC50s: 0.349 and 1.3 nM in cells) It also shows no effect on TRPC3, TRPC6, TRPV1, TRPV4, T... | |||
TCS0102 | Pulegone | (+)-Pulegone | Calcium Channel , Endogenous Metabolite , TRP/TRPV Channel |
1. Pulegone ((+)-Pulegone) has cytotoxicity followed by regenerative cell proliferation is the MOA for Pulegone-induced urothelial tumors in female rats. 2. Pulegone induces a verapamil-sensitive psychostimulant effect t... | |||
T80843 | Wasabi Receptor Toxin | WaTx | |
Wasabi Receptor Toxin (WaTx) activates TRPA1 through prolonged channel openings while reducing Ca2+ permeability. This compound has potential applications in studying both acute and persistent pain [1]. | |||
T38372 | 2-Fluoro-4-iodo benzonitrile | Others | |
2-Fluoro-4-iodo benzonitrile is a building block.1,2It has been used in the synthesis ofL. infantumtrypanothione reductase (Li-TryR) dimerization and oxidoreductase activity inhibitors.12-Fluoro-4-iodo benzonitrile has a... | |||
T31995 | GRC-17536 | GRC17536,GRC 17536 | Others |
GRC-17536 is an orally available, potent, and selective transient receptor potential anchor protein 1 (TRPA1) inhibitor that has been shown to be highly effective in the treatment of inflammation and neuropathic pain in ... |