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Search Results for " tgf-β2 "

Targets

5

Compounds

9

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T3636 (E)-SIS3 SIS3,SIS3 HCl TGF-beta/Smad
(E)-SIS3 (SIS3), a selective Smad3 inhibitor, can attenuate TGF-β1-dependent Smad3 phosphorylation and DNA binding. It has no effect on p38 MAPK, Smad2, ERK or PI3K signaling. It also inhibits TGF-β1-induced myofibroblas...
T2386 Pirfenidone S-7701,AMR-69,S-7701,AMR69 CCR , TGF-beta/Smad
Pirfenidone (AMR69) is an inhibitor for TGF-β production and TGF-β stimulated collagen production. Pirfenidone inhibits fibroblast, epidermal, platelet-derived, and transforming beta-1 growth factors, thereby slowing tum...
T74204 Trabedersen
Trabedersen (AP 12009), an antisense oligodeoxynucleotide, specifically targets and inhibits TGF-β2 (TGF-beta/Smad), making it useful for researching malignant brain tumors and other solid tumors with high TGF-β2 express...
T77057 Lerdelimumab
Lerdelimumab (CAT-152) is a recombinant human monoclonal antibody of the IgG4 subclass targeting TGF-β2. It holds potential as an anti-scarring agent in glaucoma research [1] [2].
T71119 Netarsudil free base
Netarsudil, also known as AR-11324, is a Rho-associated protein kinase inhibitor. Netarsudil is potential useful for treating glaucoma and/or reducing intraocular pressure. Netarsudil Increases Outflow Facility in Hum...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-00413 TGF beta 2 Protein, Mouse, Recombinant (His) Mouse HEK293
TGF beta 2 (Transforming growth factor beta 2), an extracellular glycosylated protein, which belongs to the TGF-beta family. TGF-beta regulates key mechanisms of tumor development, namely immunosuppression, metastasis, a...
TMPJ-00261 TGF beta 2 Protein, Mouse/Rat, Recombinant Mouse,Rat Human Cells
Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofaci...
TMPJ-00258 TGF beta 2 Protein, Human, Recombinant Human Human Cells
Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. T...
TMPY-05314 TGF beta 2 Protein, Mouse, Recombinant (His), Biotinylated Mouse HEK293
TGF beta 2 (Transforming growth factor beta 2), an extracellular glycosylated protein, which belongs to the TGF-beta family. TGF-beta regulates key mechanisms of tumor development, namely immunosuppression, metastasis, a...
TMPY-00231 TGF beta 2 Protein, Canine, Recombinant (His) Canine HEK293
TGF beta 2 (Transforming growth factor beta 2), an extracellular glycosylated protein, which belongs to the TGF-beta family. TGF-beta regulates key mechanisms of tumor development, namely immunosuppression, metastasis, a...
TMPY-04577 TGF beta 2 Protein, Rhesus, Recombinant (His) Rhesus HEK293
TGF beta 2 (Transforming growth factor beta 2), an extracellular glycosylated protein, which belongs to the TGF-beta family. TGF-beta regulates key mechanisms of tumor development, namely immunosuppression, metastasis, a...
TMPJ-00260 Latent TGF-beta 2 Protein, Human, Recombinant (His & Avi), Biotinylated Human Human Cells
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are...
TMPJ-00259 TGF beta 2 Protein, Human, Recombinant (Avi), Biotinylated Human Human Cells
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are...
TMPJ-00771 TGF beta 1 Protein, Mouse/Rat, Recombinant Mouse,Rat Human Cells
Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differen...
Cat No. Product Name
L4100 TGF-beta/Smad Compound Library

184 compounds
A unique collection of 184 TGF-beta/Smad signaling targeted compounds for high throughput and high content screening;
TargetMol