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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T0459 | Sulindac | Arthrocine,MK-231,Clinoril,Sulindac sulfoxide | COX , Autophagy |
Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity. Converted in vivo to an active metabolite, sulindac, a nonsteroidal anti-inflammatory drug (NSAID), blocks cycl... | |||
T13037 | Sulindac sulfide | cis-Sulindac sulfide | Raf , Others , AChR |
Sulindac sulfide (cis-Sulindac sulfide) is a non-steroidal anti-inflammatory compound that has a high affinity for COX-1 and acts as an inhibitor in Ras activation of Raf-1. Sulindac sulfide is a non-competitive inhibito... | |||
T23403 | Sulindac sulfone | Reductase , COX | |
Sulindac sulfone is a metabolite of the nonsteroidal anti-inflammatory drug sulindac. | |||
T24051 | Exisulind | Sulindac sulfone,CP248 | Apoptosis , PKA |
Exisulind (CP248) induces apoptosis through the activation of protein kinase G (PKG). Exisulind exhibits antineoplastic activity in solid tumour and haematological cancer cell lines and is an inhibitor of tumour growth i... | |||
T61585 | Sulindac sodium | ||
Sulindac (sodium) (MK-231) is an orally active nonsteroidal anti-inflammatory agent. Sulindac (sodium) is used to reduce pain, swelling, and joint stiffness from arthritis. Sulindac is also used for the research of arthr... | |||
T68027 | (Z/E)-cp-461 free base | ||
CP-461 is an orally bioavailable second-generation selective apoptotic antineoplastic drug (SAAND) and analog of the nonsteroidal anti-inflammatory drug (NSAID) sulindac, with potential pro-apoptotic and antineoplastic a... |