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Search Results for " sulindac "

6

Compounds

Cat No. Product Name Synonyms Targets
T0459 Sulindac Arthrocine,MK-231,Clinoril,Sulindac sulfoxide COX , Autophagy
Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity. Converted in vivo to an active metabolite, sulindac, a nonsteroidal anti-inflammatory drug (NSAID), blocks cycl...
T13037 Sulindac sulfide cis-Sulindac sulfide Raf , Others , AChR
Sulindac sulfide (cis-Sulindac sulfide) is a non-steroidal anti-inflammatory compound that has a high affinity for COX-1 and acts as an inhibitor in Ras activation of Raf-1. Sulindac sulfide is a non-competitive inhibito...
T23403 Sulindac sulfone Reductase , COX
Sulindac sulfone is a metabolite of the nonsteroidal anti-inflammatory drug sulindac.
T24051 Exisulind Sulindac sulfone,CP248 Apoptosis , PKA
Exisulind (CP248) induces apoptosis through the activation of protein kinase G (PKG). Exisulind exhibits antineoplastic activity in solid tumour and haematological cancer cell lines and is an inhibitor of tumour growth i...
T61585 Sulindac sodium
Sulindac (sodium) (MK-231) is an orally active nonsteroidal anti-inflammatory agent. Sulindac (sodium) is used to reduce pain, swelling, and joint stiffness from arthritis. Sulindac is also used for the research of arthr...
T68027 (Z/E)-cp-461 free base
CP-461 is an orally bioavailable second-generation selective apoptotic antineoplastic drug (SAAND) and analog of the nonsteroidal anti-inflammatory drug (NSAID) sulindac, with potential pro-apoptotic and antineoplastic a...
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