scopolamine — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T0253	Methscopolamine	Methscopolamine bromide,Hyoscine methyl bromide,(-)-Scopolamine methyl bromide	AChR
	Methscopolamine (Hyoscine methyl bromide) (Pamine), as a natural plant alkaloid, is a muscarinic acetylcholine receptor blocker.		AChR
T0333	Aniracetam	Ro 13-5057	Dopamine Receptor , 5-HT Receptor , GluR , AChR , iGluR
	Aniracetam (Ro 13-5057)(Ro 13-5057), a nootropic and neuroprotective drug, selectively modulates the AMPA receptor and nAChR.		Dopamine Receptor , 5-HT Receptor , GluR , AChR , iGluR
TN1994	Norscopolamine		Others
	Norscopolamine is a natural product		Others
T34435	RU 47213	RU-47213,Itameline,RU47213	Others
	RU 47213 can be used to inhibit scopolamine-induced working memory impairment in rats.		Others
T77678	TZ3O		AChR
	TZ3O is an anticholinergic compound with neuroprotective activity.TZ3O ameliorates memory impairment and cognitive decay in Scopolamine-induced Alzheimer's type model in rats, and can be used in the study of Alzheimer's ...		AChR
TN2230	Soyasaponin Ba		Others
	Soyasaponin Ba may represent viable candidates for effective vaccine adjuvants due to their higher and lower or non-haemolytic effects.Soyasaponins Ab and Bb prevent scopolamine-induced memory impairment in mice without ...		Others
T21532	Anisodamine	6-Hydroxyhyoscyamine,6-beta-Hydroxyhyoscyamine	AChR
	Anisodamine (6-beta-Hydroxyhyoscyamine) is an antagonist of muscarinic and nicotinic cholinoceptor with similar affinities at the muscarinic receptor as scopolamine and atropine. Anisodamine improve the microcirculation ...		AChR
T5702	Tenuifoliside B		Dehydrogenase
	Tenuifoliside B is a natural product from the roots of Polygala tenuifolia.And is a target lactate dehydrogenase inhibitor. Tenuifoliside B has cognitive improving and cerebral protective effects. it can inhibit potassi...		Dehydrogenase
T5595	Tropine	3alpha-Tropanol,Pseudotropine	Others
	Tropine is a naturally-occurring tropane alkaloid extracted primarily from plants of the Solanaceae family. It serves as an intermediate in the synthesis of a variety of bioactive alkaloids.		Others
T38192	Unifiram		Others
	Unifiram is a nootropic agent.1It increases acetylcholine (ACh) release in the rat cerebral cortexin vivoand induces a long-lasting increase in the amplitude of field excitatory postsynaptic potentials (fEPSPs) in the ra...		Others
T32800	Littorine	(R)-(-)-Littorine
	Littorine is a tropane alkaloid found in a variety of plants including Datura and Atropa belladonna. It is closely related in chemical structure to atropine, hyoscyamine, and scopolamine, which all share a common biosynt...
T81072	Suffruticosol A
	Suffruticosol A, a neuroprotective compound isolated from the seeds of P. lactiflora [1], mitigates scopolamine-induced neurodegenerative cellular damage and improves hippocampal cholinergic function. Additionally, it pa...
T79621	TZ4M
	TZ4M, a 2,4-thiazolidinedione (TZD)-based anti-ADV agent, exhibits neuroprotective effects and acetylcholinesterase (AChE) inhibition in human plasma. It enhances memory and cognitive function in adult rats within a scop...
T64036	5-HT6R/MAO-B modulator 1
	5-HT6R/MAO-B modulator 1 is an antagonist of 5-HT6R at Gs signaling and an irreversible inhibitor of MAO-B that exhibits glial protective activity. 5-HT6R/MAO-B modulator 1 exhibits induction of scopolamine-induced memor...
T81335	PZ-1922		5-HT Receptor
	PZ-1922 (Compound 16), able to cross the blood-brain barrier, is a dual antagonist for 5-HT6R and 5-HT3R with K i values of 17 nM and 0.45 nM, respectively. It also reversibly inhibits MAO-B with a pIC50 of 8.93. Moreove...		5-HT Receptor
T78739	PD07
	PD07 is an orally active acetylcholinesterase (AChE) inhibitor, exhibiting an IC50 of 0.29 μM against human AChE, and demonstrates inhibition of cholinesterases (ChEs), β-site amyloid precursor protein cleaving enzyme 1 ...
T76229	P3Ysh-3
	p3Ysh-3, a peptide inhibitor targeting the STEP Phosphatase-GluA2 AMPA receptor interaction, exhibits a Ki of 1.09 μM. It effectively reverses memory deficits and demonstrates anxiolytic and antidepressant effects in sco...
T76230	P-fin4
	p-fin4 is a peptide inhibitor targeting the interaction between STEP Phosphatase and GluA2 AMPA receptor, exhibiting a Ki of 0.4 μM. This compound has been shown to reverse memory deficits and exert anxiolytic and antide...
T12738	Rivanicline hemioxalate	RJR-2403 hemioxalate,(E)-Metanicotine hemioxalate	Others
	Rivanicline hemioxalate, also known as RJR-2403 hemioxalate or (E)-Metanicotine hemioxalate, is a chemical compound acting as a neuronal nicotinic receptor agonist with pronounced selectivity for the α4β2 receptor subtyp...		Others
T37388	Afizagabar
	Afizagabar (S44819) is a first-in-class, competitive, and selective antagonist at the GABA-binding site of the α5-GABAAR, with an IC50 of 585 nM for α5β2γ2 and a Ki of 66 nM for α5β3γ2. Afizagabar enhances hippocampal sy...