sp600125 — TargetMol Chemicals

Search Result

Search Results for " sp600125 "

Compounds

Cat No.	Product Name	Synonyms	Targets
T3109	SP600125	1PMV,JNK Inhibitor II,Nsc75890,Pyrazolanthrone	Apoptosis , Ferroptosis , Trk receptor , JNK , Aurora Kinase , Autophagy
	SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitive properties. SP600125 inhibits autophagy and induces apoptosis.
T79754	JNK-IN-14		JNK
	JNK-IN-14 is a potent inhibitor of JNK with IC50 values of 1.81 nM for JNK1, 12.7 nM for JNK2, and 10.5 nM for JNK3. It induces early-stage apoptosis, arrests cell population at the G2/M phase, and moderately inhibits be...		JNK
T79296	JNK-IN-12		JNK
	JNK-IN-12 (compound P2) is a mitochondrial-targeted JNK inhibitor with an IC50 value of 66.3 nM, comprising a mitochondrial-specific cell-penetrating peptide linked to SP600125, a selective JNK inhibitor. It selectively ...		JNK
T36673	CC 401 dihydrochloride
	High affinity JNK inhibitor (Ki values are 25-50 nM). Inhibits JNK via competitive binding of the ATP-binding site of active, phosphorylated JNK. Exhibits > 40-fold selectivity for JNK over p38, ERK, IKK2, protein kinase...