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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T12747 | ROCK2-IN-2 | ROCK | |
ROCK2-IN-2 is a selective inhibitor of ROCK2 (IC50 of <1 μM). | |||
T79832 | ROCK2-IN-6 | ROCK | |
ROCK2-IN-6 (Comp A) is a selective inhibitor of ROCK2, applicable in the study and treatment of ROCK-mediated, autoimmune, and inflammatory diseases [1]. | |||
T81261 | ROCK2-IN-7 | ROCK | |
ROCK2 inhibitor is a chemical compound associated with the therapeutic management of psoriasis. It exhibits its efficacy in targeting ROCK2 enzymes within HaCaT cells and has demonstrated beneficial effects in a psoriasi... | |||
T73117 | ROCK2-IN-5 | ||
ROCK2-IN-5, a compound integrating structural elements from the Rho kinase inhibitor fasudil and the NRF2 inducers caffeic and ferulic acids, exhibits a favorable multitarget profile and tolerability. It shows potential ... | |||
T78205 | ROCK2-IN-6 hydrochloride | ROCK | |
ROCK2-IN-6 hydrochloride (Comp A) serves as a selective inhibitor of ROCK2, applicable for research into ROCK-mediated diseases, autoimmune disorders, and inflammation [1]. | |||
T3518 | GSK269962A | GSK269962B,GSK 269962,GSK269962A HCl | ROCK , S6 Kinase |
GSK269962A (GSK269962A HCl) is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively. | |||
T6867 | Belumosudil | KD025,Rezurock,ROCK inhibitor,SLx-2119 | ROCK |
Belumosudil (Rezurock) is an orally available, and specific ROCK2 inhibitor (IC50/Ki: 60/41 nM). | |||
TQ0187 | SR-3677 | ROCK , Autophagy | |
SR-3677 is an effective and specific inhibitor of ROCK2 (IC50: 3 nM). | |||
T15798 | LX7101 | ROCK , LIM Kinase , PKA | |
LX7101 is an effective inhibitor of LIMK and ROCK2 (IC50: 24, 1.6, and 10 nM for LIMK1, LIMK2, and ROCK2, respectively). It also inhibits PKA (IC50 <1 nM). | |||
T12746 | ROCK inhibitor-2 | ROCK | |
ROCK inhibitor-2 is a selective dual inhibitor of ROCK1 and ROCK2 (IC50s of 17 nM and 2 nM, respectively). | |||
T4276L | Hydroxyfasudil | Hydroxy-Fasudil,HA-1100 | ROCK , PKA |
Hydroxyfasudil (Hydroxy-Fasudil) is a ROCK inhibitor(IC50s of 0.73 and 0.72 μM for ROCK1 and ROCK2, respectively). | |||
T13419 | ROCK-IN-1 | ROCK | |
ROCK-IN-1 is a potent ROCK inhibitor that inhibits ROCK2-mediated signaling with an IC50 value of 1.2 nM.ROCK-IN-1 can be used in the study of neurological disorders and inflammation-related diseases. | |||
T22037 | AS 1892802 | ROCK | |
AS 1892802 is a potent and selective inhibitor of ROCK. AS 1892802 exibits IC50 values of 52nM, 57nM and 122 nM for human ROCK2, rat ROCK2 and human ROCK1, respectively. The onset of antinociceptive effect of AS 1892802 ... | |||
TQ0319 | Ripasudil | K-115,Ripasudil hydrochloride dihydrate | ROCK |
Ripasudil (Ripasudil hydrochloride dihydrate) (K-115) hydrochloride dihydrate is a specific ROCK inhibitor (IC50s: 51/19 nM for ROCK1/ROCK2). | |||
T1898 | RKI-1447 | RKI1447 | ROCK |
RKI-1447 is a potent inhibitor of ROCK1 and ROCK2. It has anti-invasive and antitumor activities. | |||
T14960 | Chroman 1 | ROCK | |
Chroman 1 is an inhibitor of ROCK2 (IC50: 1 nM). | |||
T7301 | BDP5290 | ROCK | |
BDP5290 is a potent inhibitor of both ROCK and MRCK(IC50s of 5 nM, 50 nM, 10 nM and 100 nM for ROCK1, ROCK2, MRCKα and MRCKβ, respectively.) | |||
T12721 | Rho-Kinase-IN-1 | ROCK | |
Rho-Kinase-IN-1 is an inhibitor of ROCK with Kis of 30.5 nM and 3.9 nM for ROCK1 and ROCK2, respectively. Rho-Kinase-IN-1 can be used in studies about excessive cell proliferation, remodeling, edema and inflammation dise... | |||
T4276 | Hydroxyfasudil Hydrochloride | Hydroxyfasudil (HA-1100) HCl,HA 1100 hydrochloride | ROCK |
Hydroxyfasudil Hydrochloride (HA 1100 hydrochloride) is a ROCK1/2 inhibitor (IC50s: 0.73/0.72 μM). | |||
T23308 | SAR407899 hydrochloride | ROCK | |
ATP-competitive ROCK inhibitor |