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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T71029 | RCC-36 HCl | ||
Rcc 36 is an active metabolite of temiverine that has inhibitory actions toward the atropine-resistant part of contractions, which may be related to the calcium antagonistic actions of these compounds. | |||
T26046 | Razoxane | Topoisomerase | |
Razoxane is used as an antimitotic agent with immunosuppressive properties. | |||
T6683 | STF-62247 | STF 62247 | Estrogen/progestogen Receptor , Autophagy |
STF-62247 is TGN inhibitor with IC50 of 0.625 μM and 16 μM in RCC4 and RCC4/VHL cells, respectively. | |||
T9698 | UC2288 | Mdm2 , p53 | |
UC2288 is a relatively selective p21 attenuator which is synthesized based Sorafenib. UC2288 attenuates p21 protein levels with minimal effect on p21 protein stability. | |||
T71027 | KDI-792 hydrochloride | ||
KDI-792 hydrochloride is a thromboxane dual blocker. | |||
T60904 | ERCC1-XPF-IN-2 | Others | |
ERCC1-XPF-IN-2 is active in nucleotide excision repair, cisplatin enhancement and γH2AX assays. ERCC1-XPF-IN-2 is a potent inhibitor of ERCC1-XPF endonuclease with an IC 50 value of 0.6 μM [1]. | |||
T63464 | ERCC1-XPF-IN-1 | ||
ERCC1-XPF-IN-1 is a potent, high-affinity inhibitor of ERCC1-XPF (IC50: 0.49 μM). ERCC1-XPF-IN-1 inhibits the removal of CPDs, reduces the toxicity of cyclophosphamide to colorectal cancer cells, enhances the cytotoxic e... | |||
T14318 | ARCC-4 | Others | |
ARCC-4 is an enzalutamide-based von Hippel-Lindau (VHL)-recruiting AR PROTAC and outperforms enzalutamide and it is a low-nanomolar androgen receptor (AR) degrader based on PROTAC, with a DC50 of 5 nM. ARCC-4 effectively... | |||
T41227 | ARCC 4 negative control | ||
ARCC 4 negative control is a negative control for ARCC 4. Binds androgen receptors (AR) without inducing degradation. | |||
T63505 | Tivozanib hydrochloride hydrate | ||
Tivozanib hydrochloride hydrate is a selective, potent, orally active VEGFR tyrosine kinase inhibitor that acts on VEGFR-1 (IC50: 0.21 nM), VEGFR-2 (IC50: 0.16 nM), and VEGFR-3 (IC50: 0.24 nM). Tivozanib hydrochloride hy... | |||
T76723 | Tilvestamab | ||
Tilvestamab (BGB149), a humanized anti-AXL antibody, effectively blocks AXL-mediated cell signaling, significantly reduces Gas6-induced AXL activation, and inhibits downstream AKT phosphorylation in 786-0-Luc RCC cells. ... |