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Search Results for " ps2 "

Targets

5

Compounds

11

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T16670 PS210 PDK
PS210 is a potent and selective activator of PDK1 (Kd: 3 μM), specifically targeting the PIF-binding pocket of PDK1, without acting against other protein kinases such as S6K, PKB/Akt, or GSK3. Its prodrug, PS423, serves ...
T8457 NPS2390 GluR
NPS2390 is a first generation quinoxaline derivative that acts as a noncompetitive antagonist of mGluR1 and mGluR5 (IC50 of 5.2 and 82 nM, respectively)
T74181 CPS2
CPS2, a first-in-class, highly potent, selective, and irreversible PROTAC CDK2 degrader (IC 50 = 24 nM), is utilized in the research of acute myeloid leukemia [1].
T12639 (R)-PS210 Others
(R)-PS210, the R enantiomer of PS210 is a substrate-selective allosteric PDK1 activator with an (AC50 of 1.8 μM).
T11178 ELN318463 ELN 318463 Others
ELN 318463 shows differential inhibition of presenilin (PS1)- and PS2-comprised γ-secretase with EC50s of 12 nM and 656 nM for PS1 and PS2, respectively. ELN 318463 is 51-fold more selective for PS1.ELN 318463 is an amyl...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPJ-01089 TFF1 Protein, Mouse, Recombinant (His) Mouse Human Cells
Trefoil Factor 1 (TFF1) belongs to the three structurally related secreted proteins that contain trefoil domains.TFF1 is an approximately peptide that has an important effect in epithelial regeneration and wound healing...
TMPY-05431 TFF1 Protein, Human, Recombinant (His) Human HEK293
TFF1 Protein, Human, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 8.1 kDa. Accession number: P04155
TMPK-00007 TFF1 Protein, Human, Recombinant (hFc) Human HEK293
Breast cancer (BC) is the most common cancer in women and the second leading cause of their cancer death. Establishing an accurate BC prognosis is very difficult because of its heterogeneity. Elevated TFF1 levels in seru...
TMPK-00941 TFF1 Protein, Mouse, Recombinant (hFc) Mouse HEK293
Breast cancer (BC) is the most common cancer in women and the second leading cause of their cancer death. Establishing an accurate BC prognosis is very difficult because of its heterogeneity. Elevated TFF1 levels in seru...
TMPK-01315 PS20 Protein, Cynomolgus, Recombinant (His) Cynomolgus E. coli
The whey acidic protein family member, WFDC1/ps20 is a permissivity factor in HIV infection. Herein we describe a contrasting role for ps20 in limiting MHV-1 infection. Intranasal MHV-1 infection produces a respiratory i...
TMPK-01189 PS20 Protein, Human, Recombinant (His) Human E. coli
The whey acidic protein family member, WFDC1/ps20 is a permissivity factor in HIV infection. Herein we describe a contrasting role for ps20 in limiting MHV-1 infection. Intranasal MHV-1 infection produces a respiratory i...
TMPK-01173 PS20 Protein, Mouse, Recombinant (His) Mouse E. coli
The whey acidic protein family member, WFDC1/ps20 is a permissivity factor in HIV infection. Herein we describe a contrasting role for ps20 in limiting MHV-1 infection. Intranasal MHV-1 infection produces a respiratory i...
TMPY-04768 PRPS2 Protein, Human, Recombinant (His) Human E. coli
PRPS2, a subset of PRS, is reported to be a potential protein associated with Sertoli-cell only syndrome. PRPS2 expression correlates with Sertoli-cell only syndrome and inhibits the apoptosis of TM4 Sertoli cells via th...
TMPH-00462 COPS2 Protein, Danio rerio, Recombinant (His) Danio rerio (Zebrafish) Yeast
COPS2 Protein, Danio rerio, Recombinant (His) is expressed in Yeast.
TMPH-01137 COPS2 Protein, Human, Recombinant (His) Human Yeast
COPS2 Protein, Human, Recombinant (His) is expressed in Yeast.
TMPH-00461 COPS2 Protein, Danio rerio, Recombinant (E. coli, His) Danio rerio (Zebrafish) E. coli
COPS2 Protein, Danio rerio, Recombinant (E. coli, His) is expressed in E. coli.
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