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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T16518 | PH-002 | Others | |
PH-002, an inhibitor targeting the intramolecular domain interaction of apolipoprotein (apo) E4 in neuronal cells, additionally enhances mitochondrial motility and promotes neurite outgrowth, thereby countering related i... | |||
T8885 | 5-Ph-IAA | Others | |
5-Ph-IAA is a derivative of Indole-3-acetic acid (IAA), which is a plant hormone and acts as an enzyme or prodrug combination for cancer gene therapy. | |||
T1974 | PH-797804 | PH797804 | p38 MAPK , Autophagy |
PH-797804 is a pyridinone inhibitor of p38α (IC50: 26 nM, in a cell-free assay); 4-fold more selective versus p38β and does not inhibit JNK2. | |||
T18794 | Tetrazine-Ph-NHCO-C3-NHS ester | Others , PROTAC Linker | |
Tetrazine-Ph-NHCO-C3-NHS ester is a PEG-derived linker for PROTACs synthesis. | |||
T17372 | Ald-Ph-NHS ester | Others | |
Ald-Ph-NHS ester is a non-cleavable linker used in antibody-drug-conjugation (ADC). | |||
T18476 | N3-Ph-NHS ester | Others | |
N3-Ph-NHS ester is a noncleavable ADC linker. N3-Ph-NHS ester can be used in the synthesis of antibody-drug conjugates (ADCs). | |||
T7756 | Pomalidomide-PEG4-Ph-NH2 | Ligand for E3 Ligase | |
Pomalidomide-PEG4-Ph-NH2 is a synthetic E3 ligase ligand-linker conjugate combining a Pomalidomide-based cereblon ligand and a 4-unit PEG linker. | |||
T16486 | Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD | PF-05231023 | FGFR , PROTAC Linker |
Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD (PF-05231023) is a long-acting fibroblast growth factor 21 (FGF21) analog and is an FGF21-receptor agonist. It is also suitable for development as a potential treatment for T2DM. | |||
T7055 | Bz-RS-ISer(3-Ph)-Ome | Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate | Others , HIV Protease |
Bz-RS-ISer(3-Ph)-Ome (Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate) is a paclitaxel derivative that inhibits the HSV replication cycle at low cytotoxicity, blocks mitosis in Vero cells, affects the size o... | |||
T40203 | AZD-CO-Ph-PEG4-Ph-CO-AZD | AZD-CO-Ph-PEG4-Ph-CO-AZD | |
AZD-CO-Ph-PEG4-Ph-CO-AZD is a bis-β-lactam linker, commonly employed in the synthesis of antibody-siRNA conjugates. | |||
T16519 | PH-064 | BIM-46187 | Others |
PH-064 (BIM-46187) is a heterotrimeric G-protein complex inhibitor. | |||
T68180 | Ph CL 28A | ||
Ph CL 28A is a 15-hydroxyprostaglandin dehydrogenase inhibitor. | |||
T40754 | M-PEG2-O-Ph-NH2 | m-PEG2-O-Ph-NH2 | |
m-PEG2-O-Ph-NH2 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system w... | |||
T38667 | Mal-Ph-CONH-PEG4-NHS ester | Mal-Ph-CONH-PEG4-NHS ester | |
Mal-Ph-CONH-PEG4-NHS ester, a non-cleavable four-unit polyethylene glycol (PEG) ADC linker, plays a crucial role in the synthesis of antibody-drug conjugates (ADCs). | |||
T18801 | Tetrazine-Ph-PEG5-Ph-tetrazine | Others | |
Tetrazine-Ph-PEG5-Ph-tetrazine is a PEG-based PROTAC linker utilized for the synthesis of PROTACs[1]. | |||
T18800 | Tetrazine-Ph-PEG4-Ph-aldehyde | Others | |
Tetrazine-Ph-PEG4-Ph-aldehyde is a polyethylene glycol (PEG) derived linker, specifically designed for the synthesis of proteolysis-targeting chimeras (PROTACs)[1]. | |||
T33958 | PH 1008 | PH1008,PH-1008 | |
PH 1008 is a porphyrin photosensitizer that may be useful as a diagnostic tool. | |||
T16519L | BIM-46187 4HCl | PH-064 4HCl | Others |
BIM-46187 4HCl (PH-064 4HCl) is a heterotrimeric G-protein complex inhibitor. | |||
T39535 | Ald-Ph-amido-PEG3-NHS ester | Ald-Ph-amido-PEG3-NHS ester | |
Ald-Ph-amido-PEG3-NHS ester is a non-cleavable 3-unit PEG linker specifically designed for the synthesis of antibody-drug conjugates (ADCs). It is utilized as a chemical compound in connecting antibodies and drugs, formi... | |||
T38632 | Ald-Ph-amido-PEG11-NH-Boc | Ald-Ph-amido-PEG11-NH-Boc | |
Ald-Ph-amido-PEG11-NH-Boc is a non-cleavable 11-unit polyethylene glycol (PEG) linker employed in the synthesis of antibody-drug conjugates (ADCs). |