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20

Compounds

Cat No. Product Name Synonyms Targets
T16518 PH-002 Others
PH-002, an inhibitor targeting the intramolecular domain interaction of apolipoprotein (apo) E4 in neuronal cells, additionally enhances mitochondrial motility and promotes neurite outgrowth, thereby countering related i...
T8885 5-Ph-IAA Others
5-Ph-IAA is a derivative of Indole-3-acetic acid (IAA), which is a plant hormone and acts as an enzyme or prodrug combination for cancer gene therapy.
T1974 PH-797804 PH797804 p38 MAPK , Autophagy
PH-797804 is a pyridinone inhibitor of p38α (IC50: 26 nM, in a cell-free assay); 4-fold more selective versus p38β and does not inhibit JNK2.
T18794 Tetrazine-Ph-NHCO-C3-NHS ester Others , PROTAC Linker
Tetrazine-Ph-NHCO-C3-NHS ester is a PEG-derived linker for PROTACs synthesis.
T17372 Ald-Ph-NHS ester Others
Ald-Ph-NHS ester is a non-cleavable linker used in antibody-drug-conjugation (ADC).
T18476 N3-Ph-NHS ester Others
N3-Ph-NHS ester is a noncleavable ADC linker. N3-Ph-NHS ester can be used in the synthesis of antibody-drug conjugates (ADCs).
T7756 Pomalidomide-PEG4-Ph-NH2 Ligand for E3 Ligase
Pomalidomide-PEG4-Ph-NH2 is a synthetic E3 ligase ligand-linker conjugate combining a Pomalidomide-based cereblon ligand and a 4-unit PEG linker.
T16486 Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD PF-05231023 FGFR , PROTAC Linker
Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD (PF-05231023) is a long-acting fibroblast growth factor 21 (FGF21) analog and is an FGF21-receptor agonist. It is also suitable for development as a potential treatment for T2DM.
T7055 Bz-RS-ISer(3-Ph)-Ome Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate Others , HIV Protease
Bz-RS-ISer(3-Ph)-Ome (Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate) is a paclitaxel derivative that inhibits the HSV replication cycle at low cytotoxicity, blocks mitosis in Vero cells, affects the size o...
T40203 AZD-CO-Ph-PEG4-Ph-CO-AZD AZD-CO-Ph-PEG4-Ph-CO-AZD
AZD-CO-Ph-PEG4-Ph-CO-AZD is a bis-β-lactam linker, commonly employed in the synthesis of antibody-siRNA conjugates.
T16519 PH-064 BIM-46187 Others
PH-064 (BIM-46187) is a heterotrimeric G-protein complex inhibitor.
T68180 Ph CL 28A
Ph CL 28A is a 15-hydroxyprostaglandin dehydrogenase inhibitor.
T40754 M-PEG2-O-Ph-NH2 m-PEG2-O-Ph-NH2
m-PEG2-O-Ph-NH2 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system w...
T38667 Mal-Ph-CONH-PEG4-​NHS ester Mal-Ph-CONH-PEG4-NHS ester
Mal-Ph-CONH-PEG4-NHS ester, a non-cleavable four-unit polyethylene glycol (PEG) ADC linker, plays a crucial role in the synthesis of antibody-drug conjugates (ADCs).
T18801 Tetrazine-Ph-PEG5-Ph-tetrazine Others
Tetrazine-Ph-PEG5-Ph-tetrazine is a PEG-based PROTAC linker utilized for the synthesis of PROTACs[1].
T18800 Tetrazine-Ph-PEG4-Ph-aldehyde Others
Tetrazine-Ph-PEG4-Ph-aldehyde is a polyethylene glycol (PEG) derived linker, specifically designed for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
T33958 PH 1008 PH1008,PH-1008
PH 1008 is a porphyrin photosensitizer that may be useful as a diagnostic tool.
T16519L BIM-46187 4HCl PH-064 4HCl Others
BIM-46187 4HCl (PH-064 4HCl) is a heterotrimeric G-protein complex inhibitor.
T39535 Ald-Ph-amido-PEG3-NHS ester Ald-Ph-amido-PEG3-NHS ester
Ald-Ph-amido-PEG3-NHS ester is a non-cleavable 3-unit PEG linker specifically designed for the synthesis of antibody-drug conjugates (ADCs). It is utilized as a chemical compound in connecting antibodies and drugs, formi...
T38632 Ald-Ph-amido-PEG11-NH-Boc Ald-Ph-amido-PEG11-NH-Boc
Ald-Ph-amido-PEG11-NH-Boc is a non-cleavable 11-unit polyethylene glycol (PEG) linker employed in the synthesis of antibody-drug conjugates (ADCs).
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