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Search Results for " panc1 "

6

Compounds

Cat No. Product Name Synonyms Targets
T12006 Metarrestin ML246 DNA/RNA Synthesis
Metarrestin (ML246) is a first-in-class perinucleolar compartment inhibitor with a favorable PK profile, which effectively suppresses metastasis. Metarrestin disrupts the nucleolar structure and inhibits RNA polymerase (...
T8800 NSAH 2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide DNA/RNA Synthesis
NSAH (2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide) is a nonnucleoside inhibitor of human ribonucleotide reductase (hRR).with cell-free IC50 of 32 μM and cell-based IC50 of ~250 nM, respectively...
T6823 E3330 HIF/HIF Prolyl-Hydroxylase , DNA/RNA Synthesis
E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.
T11593 I-OMe-Tyrphostin AG 538 I-OMe-AG 538 IGF-1R , PI3K
I-OMe-Tyrphostin AG 538 is a specific IGF-1R inhibitor and ATP-competitive inhibitor of PI5P4Kα (IC50: 1 µM).I-OMe-Tyrphostin AG 538 inhibits IGF-1R-mediated signaling and exhibits preferential cytotoxicity to nutrient-d...
TN2967 Pinobanksin 3-acetate 3-O-Acetylpinobanksin Others , Antioxidant
Pinobanksin 3-acetate (3-O-Acetylpinobanksin), a flavonoid derivative, is a strong antioxidant found in sunflowers and honey that inhibits LDL peroxidation.
T68981 PD-321852
PD-321852 is a small-molecule Chk1 inhibitor, which potentiates gemcitabine-induced clonogenic death in a panel of pancreatic cancer cell lines and evaluated the relationship between endpoints associated with Chk1 inhibi...
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