paclitaxel — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T0968	Paclitaxel	Taxol,NSC 125973	Apoptosis , Microtubule Associated , Autophagy
	Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer. Paclitaxel has anti-tumor activity and causes cell death by inducing mitotic arrest, apoptosis, and cell autophagy.		Apoptosis , Microtubule Associated , Autophagy
T20864	7-Troc-paclitaxel		Others
	7-Troc-paclitaxel is a precursor of paclitaxel which has anti-tumor activity.		Others
T5749	10-Deacetyl-7-xylosyl paclitaxel	10-Deacetyl-7-xylosyltaxol,10-Deacetyltaxol 7-Xyloside,7-Xylosyl-10-deacetyltaxol,10-Deacetylpaclitaxel 7-Xyloside	Others , Microtubule Associated
	10-Deacetyl-7-xylosyl paclitaxel (7-Xylosyl-10-deacetyltaxol) is a Paclitaxel derivative with improved pharmacological features and higher water solubility,used in Chinese clinics to treat cancer.		Others , Microtubule Associated
T5738	7-Epi 10-desacetyl paclitaxel	10-Deacetyl-7-epipaclitaxel,7-Epi-10-deacetyltaxol	Others
	7-Epi 10-desacetyl paclitaxel (10-Deacetyl-7-epipaclitaxel) shows IC50 values of 0.085 nM, against HeLa cells.		Others
T33862	Paclitaxel-Succinic acid	Paclitaxel-hemisuccinic acid
	Paclitaxel-Succinic acid (paclitaxel-succinate , paclitaxel-semisucinic acid)is a paclitaxel derivative with a succinic acid linker. Paclitaxel-Succinic acid can be used to prepare paclitaxel conjugates for drug delivery...
T5165	10-Deacetyltaxol	10-DAT,10-Desacetyl Paclitaxel,Deacetyltaxol,10-deacetyl-paclitaxel,Deacetyl Paclitaxel	Others , Microtubule Associated
	10-Deacetyltaxol (10-DAT) is extracted from Taxus brevifolia barks.		Others , Microtubule Associated
T36398	Paclitaxel octadecanedioate
	Paclitaxel octadecanedioate is a prodrug form of paclitaxel that is comprised of paclitaxel conjugated to 1,18-octadecanedioic acid.1 Unlike paclitaxel, it does not promote tubulin polymerization in vitro when used at a ...
T28289	Paclitaxel-SMCC	SMCC taxol, Taxol-SMCC, Taxol SMCC,Paclitaxel with SMCC linker,SMCC-Taxol,Paclitaxel ADC conjugate.
	Paclitaxel-SMCC is a paclitaxel derivative with a SMCC linker. (Succinimidyl-4-( N -maleimidomethyl)cyclohexane-1-carboxylate). Paclitaxel-SMCC can be used to synthesize Paclitaxel bioconjugates with enzymes, antobodies,...
T3S2372	7-epi-Taxol	7-Epitaxol,7-epi-Paclitaxel	Others , Microtubule Associated
	1. 7-epi-Taxol (7-Epitaxol) is the major derivative of taxol found in cells and that its presence does not alter, in a major way, the overall biological activity of taxol.		Others , Microtubule Associated
T33861	Paclitaxel-MVCP
	Paclitaxel-MVCP ( MC-val-cit-pab-paclitaxel )is a paclitaxel derivative with an MC-Val-Cit-PAB linker, which can be used for the preparation of Paclitaxel conjugates for drug delivery and nanomedicine research.
T36896	6α-hydroxy Paclitaxel	6alpha-hydroxypaclitaxel	Drug Metabolite
	6α-hydroxy Paclitaxel (6α-OH-PTX) is a major metabolite of the anticancer compound paclitaxel and is partially cytotoxic.		Drug Metabolite
T70006	DHA-paclitaxel
	DHA-paclitaxel, also know as Taxoprexin, is prodrug comprised of the naturally occurring omega-3 fatty acid docosahexaenoic acid (DHA) covalently conjugated to the anti-microtubule agent paclitaxel. Because tumor cells t...
T70114	Paclitaxel Ceribate
	Paclitaxel Ceribate is a mitotic inhibitor used in cancer chemotherapy.
T20265	Paclitaxel Poliglumex	CT2103,Opaxio,PG-TXL,CT-2103,PPX,CT 2103
	Paclitaxel Poliglumex is cyclohexane isolated from the bark of the Pacific yew tree.
T17343	7-O-(Amino-PEG4)-paclitaxel		Others
	7-O-(Amino-PEG4)-paclitaxel is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteas...		Others
T17344	7-O-(Cbz-N-amido-PEG4)-paclitaxel		Others
	7-O-(Cbz-N-amido-PEG4)-paclitaxel is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-p...		Others
T78546	Abraxane	Nab-Paclitaxel
	Abraxane (nab-Paclitaxel) is an albumin-bound formulation of Paclitaxel nanoparticles known for its enhanced response rates and tolerability. Leveraging albumin as a delivery vehicle, this compound achieves a favorable p...
T24557	NSC756093	NSC-756093,NSC 756093	Others
	NSC756093 potentially inhibits GBP1:PIM1 interaction. NSC756093 can be used in ovarian cancer studies.		Others
T70005	LY3325656
	LY3325656 is a GPR142 agonist suitable for clinical testing in human. LY3325656 demonstrated anti-diabetic benefits in pre-clinical studies and ADME/PK properties suitable for human dosing. LY3325656 is the first GPR1...
T64325	(4S,5R)-3-tert-butoxycarbony-2-(4-anisy)-4-phenyl-5-oxazolidinecarboxylic acid		Others
	(4S,5R)-3-tert-butoxycarbony-2-(4-anisy)-4-phenyl-5-oxazolidinecarboxylic acid a.k.a. polyene-paclitaxel side chain is used as a pharmaceutical intermediate mainly for synthesizing the drug polyene-paclitaxel.		Others