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Search Results for " pku "

Targets

5

Compounds

4

Natural Products

4

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T28424 PKUMDL-WQ-2101 Dehydrogenase
PKUMDL-WQ-2101 is a selective allosteric inhibitor of phosphoglycerate dehydrogenase with anti-tumor activity.
T36935 PKUMDL-LC-101-D04 GPX4-Activator-1d4,PKUMDL-LC-101-D04 GPX
PKUMDL-LC-101-D04 is a potent allosteric activator of glutathione peroxidase 4 (GPX4), a regulator of iron death. GPX4 activity was increased to 150% of control levels when used at a concentration of 20 μM in a cell-free...
T28425 PKUMDL-WQ-2201
PKUMDL-WQ-2201 is a selective allosteric inhibitor of phosphoglycerate dehydrogenase (PHGDH) with Anti-tumor Activity, it binds to site II.
T28423 PKUMDL-LTQ-301
PKUMDL-LTQ-301 is a potent inhibitor of HipA toxin. PKUMDL-LTQ-301 also inhibits E. coli persistence.
T82004 JNT-517
JNT-517 is an orally administered allosteric inhibitor of SLC6A19, utilized in the research of phenylketonuria (PKU) [1].
Cat No. Product Name Synonyms Targets
T7117 Sapropterin dihydrochloride Sapropterin Hydrochloride,6R-Tetrahydro-L-biopterin dihydrochloride,6R-BH4 dihydrochloride Hydroxylase
Sapropterin dihydrochloride (6R-BH4 dihydrochloride) is phenylalanine hydroxylase agonist that is approved for the treatment of BH4 responsive PKU.
T5290 (S)-2-Hydroxy-3-phenylpropanoic acid L-(−)-3-Phenyllactic acid Others , Endogenous Metabolite
(S)-2-Hydroxy-3-phenylpropanoic acid (L-(−)-3-Phenyllactic acid) is a chiral aromatic compound involved in phenylalanine metabolism. It is likely produced from phenylpyruvate via the action of lactate dehydrogenase. The ...
T5251 Phenylpyruvic acid 2-Oxo-3-phenylpropanoic acid,3-Phenylpyruvic acid Others , Endogenous Metabolite
Phenylpyruvic acid (3-Phenylpyruvic acid) is a keto-acid that is an intermediate or catabolic byproduct of phenylalanine metabolism. It has a slight honey-like odor. Levels of phenylpyruvate are normally very low in bloo...
T5308 2-Hydroxyphenylacetic acid Ortho-Hydroxyphenylacetic acid,2-HPAA,2-Hydroxybenzeneacetic Acid Others , Endogenous Metabolite
2-Hydroxyphenylacetic acid (Ortho-Hydroxyphenylacetic acid) can be found in a number of food items such as natal plum, lemon verbena, half-highbush blueberry, and parsley, which makes 2-Hydroxyphenylacetic acid a potenti...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-02707 PAH Protein, Human, Recombinant (415 Asn/Asp, His) Human Baculovirus Insect Cells
PAH (phenylalanine hydroxylase), also known as PH, belongs to the biopterin-dependent aromatic amino acid hydroxylase family. It contains 1 ACT domain, N-terminal region of PAH is thought to contain allosteric binding si...
TMPY-04400 TLK2 Protein, Human, Recombinant (aa 397-772, His & GST) Human Baculovirus Insect Cells
TLK2 Protein, Human, Recombinant (aa 397-772, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 71.3 kDa and the accession number is Q86UE8-1.
TMPY-04420 TLK1 Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
Tousled-like kinase 1 (or protein kinase ubiquitous, PKU-beta/TLK1) is a serine/threonine protein kinase that is implicated in chromatin remodeling, DNA replication and mitosis. TLK1 has a function important for proper c...
TMPY-04401 TLK2 Protein, Human, Recombinant (aa 397-772) Human Baculovirus Insect Cells
TLK2 Protein, Human, Recombinant (aa 397-772) is expressed in Baculovirus insect cells. The predicted molecular weight is 43.6 kDa and the accession number is Q86UE8-1.
TargetMol