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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T28424 | PKUMDL-WQ-2101 | Dehydrogenase | |
PKUMDL-WQ-2101 is a selective allosteric inhibitor of phosphoglycerate dehydrogenase with anti-tumor activity. | |||
T36935 | PKUMDL-LC-101-D04 | GPX4-Activator-1d4,PKUMDL-LC-101-D04 | GPX |
PKUMDL-LC-101-D04 is a potent allosteric activator of glutathione peroxidase 4 (GPX4), a regulator of iron death. GPX4 activity was increased to 150% of control levels when used at a concentration of 20 μM in a cell-free... | |||
T28425 | PKUMDL-WQ-2201 | ||
PKUMDL-WQ-2201 is a selective allosteric inhibitor of phosphoglycerate dehydrogenase (PHGDH) with Anti-tumor Activity, it binds to site II. | |||
T28423 | PKUMDL-LTQ-301 | ||
PKUMDL-LTQ-301 is a potent inhibitor of HipA toxin. PKUMDL-LTQ-301 also inhibits E. coli persistence. | |||
T82004 | JNT-517 | ||
JNT-517 is an orally administered allosteric inhibitor of SLC6A19, utilized in the research of phenylketonuria (PKU) [1]. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T7117 | Sapropterin dihydrochloride | Sapropterin Hydrochloride,6R-Tetrahydro-L-biopterin dihydrochloride,6R-BH4 dihydrochloride | Hydroxylase |
Sapropterin dihydrochloride (6R-BH4 dihydrochloride) is phenylalanine hydroxylase agonist that is approved for the treatment of BH4 responsive PKU. | |||
T5290 | (S)-2-Hydroxy-3-phenylpropanoic acid | L-(−)-3-Phenyllactic acid | Others , Endogenous Metabolite |
(S)-2-Hydroxy-3-phenylpropanoic acid (L-(−)-3-Phenyllactic acid) is a chiral aromatic compound involved in phenylalanine metabolism. It is likely produced from phenylpyruvate via the action of lactate dehydrogenase. The ... | |||
T5251 | Phenylpyruvic acid | 2-Oxo-3-phenylpropanoic acid,3-Phenylpyruvic acid | Others , Endogenous Metabolite |
Phenylpyruvic acid (3-Phenylpyruvic acid) is a keto-acid that is an intermediate or catabolic byproduct of phenylalanine metabolism. It has a slight honey-like odor. Levels of phenylpyruvate are normally very low in bloo... | |||
T5308 | 2-Hydroxyphenylacetic acid | Ortho-Hydroxyphenylacetic acid,2-HPAA,2-Hydroxybenzeneacetic Acid | Others , Endogenous Metabolite |
2-Hydroxyphenylacetic acid (Ortho-Hydroxyphenylacetic acid) can be found in a number of food items such as natal plum, lemon verbena, half-highbush blueberry, and parsley, which makes 2-Hydroxyphenylacetic acid a potenti... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02707 | PAH Protein, Human, Recombinant (415 Asn/Asp, His) | Human | Baculovirus Insect Cells |
PAH (phenylalanine hydroxylase), also known as PH, belongs to the biopterin-dependent aromatic amino acid hydroxylase family. It contains 1 ACT domain, N-terminal region of PAH is thought to contain allosteric binding si... | |||
TMPY-04400 | TLK2 Protein, Human, Recombinant (aa 397-772, His & GST) | Human | Baculovirus Insect Cells |
TLK2 Protein, Human, Recombinant (aa 397-772, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 71.3 kDa and the accession number is Q86UE8-1. | |||
TMPY-04420 | TLK1 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
Tousled-like kinase 1 (or protein kinase ubiquitous, PKU-beta/TLK1) is a serine/threonine protein kinase that is implicated in chromatin remodeling, DNA replication and mitosis. TLK1 has a function important for proper c... | |||
TMPY-04401 | TLK2 Protein, Human, Recombinant (aa 397-772) | Human | Baculovirus Insect Cells |
TLK2 Protein, Human, Recombinant (aa 397-772) is expressed in Baculovirus insect cells. The predicted molecular weight is 43.6 kDa and the accession number is Q86UE8-1. |