pdgfra — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T78843	MET/PDGFRA-IN-1		c-Met/HGFR
	MET/PDGFRA-IN-1 (compound 8c) serves as an inhibitor of MET and PDGFRA proteins, displaying an IC50 of 36 μM against MET. It impedes MET phosphorylation, thereby promoting apoptosis, and curtails the proliferation of var...		c-Met/HGFR
T78844	MET/PDGFRA-IN-2		c-Met/HGFR
	MET/PDGFRA-IN-2 (compound 8h) serves as an inhibitor of MET and PDGFRA proteins, promoting apoptosis in cells and impeding the proliferation of MET-positive cells with IC50 values of 9.7, 6.1, 12.0, 11.5, 8.6, and 34.4 μ...		c-Met/HGFR
T12396	PDGFRα kinase inhibitor 1		PDGFR
	PDGFRα kinase inhibitor 1 is a highly selective inhibitor of type II PDGFRα kinase (PDGFRα and PDGFRβ with IC50s of 132 nM and 6115 nM , respectively).		PDGFR
T8482	Ripretinib	DCC-2618	Apoptosis , VEGFR , FLT , PDGFR , c-Kit
	Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.		Apoptosis , VEGFR , FLT , PDGFR , c-Kit
T5109	Avapritinib	BLU-285	PDGFR , c-Kit
	Avapritinib (BLU-285) is a dual inhibitor of the mutant KIT receptor (KIT D816V, IC50: 0.27 nM) and PDGFRα (PDGFRα D842V, IC50: 0.24 nM).		PDGFR , c-Kit

Compounds

MET/PDGFRA-IN-1

T78843

PDGFRα kinase inhibitor 1

Target: Apoptosis, VEGFR, FLT, PDGFR, c-Kit

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01139	PDGFRA Protein, Human, Recombinant (His)	Human	HEK293
	PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived growth factor family. They are members of the class III subfami...
TMPK-00943	PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, ...
TMPK-00419	PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi)	Human	HEK293
	Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, ...
TMPK-00420	PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, ...
TMPY-05789	PDGFRA Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived growth factor family. They are members of the class III subfami...
TMPY-06921	PDGFRA Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived growth factor family. They are members of the class III subfami...
TMPY-05787	PDGFRA Protein, Mouse, Recombinant (His)	Mouse	HEK293
	PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived growth factor family. They are members of the class III subfami...
TMPY-00900	PDGFRA Protein, Human, Recombinant (hFc)	Human	HEK293
	PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived growth factor family. They are members of the class III subfami...
TMPY-03825	PDGFRA Protein, Rat, Recombinant (His)	Rat	HEK293
	PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived growth factor family. They are members of the class III subfami...
TMPY-03919	PDGFRA Protein, Rat, Recombinant (hFc)	Rat	HEK293
	PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived growth factor family. They are members of the class III subfami...
TMPY-05608	PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived growth factor family. They are members of the class III subfami...