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Search Result

Search Results for " palb "

Targets

CDK

12

Compounds

5

Natural Products

3

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T6240 Palbociclib Isethionate Palbociclib (PD0332991) Isethionate,PD 0332991 isethionate CDK
Palbociclib Isethionate (PD 0332991 isethionate) is a selective inhibitor of CDK4/6 (IC50s: 11/16 nM). It exhibits no inhibition against a panel of 36 additional protein kinases.
T1785 Palbociclib PD 0332991 CDK
Palbociclib (PD 0332991) is a CDK inhibitor that inhibits CDK4 and CDK6 (IC50=11/16 nM) and is orally active. Palbociclib has anti-tumorigenic activity and has investigational potential for use in ER-positive and HER2-ne...
T6239 Palbociclib monohydrochloride PD 0332991 hydrochloride,Palbociclib hydrochloride,Palbociclib (PD-0332991) HCl CDK
Palbociclib monohydrochloride (PD 0332991 hydrochloride) is a selective inhibitor of CDK4/6 (IC50s: 11/16 nM). It exhibits no inhibition against a panel of 36 additional protein kinases.
T18515 Palbociclib-propargyl PROTAC CDK6 ligand 1 Others
Palbociclib-propargyl, a PROTAC ligand targeting the protein CDK6, connects to the CRBN ligand through a PEG linker to form PROTAC CP-10. CP-10 exhibits a potent DC50 value of 2.1 nM against CDK6[1].
T78130 N-Methyl Palbociclib Drug Metabolite
N-Methyl Palbociclib is an impurity of the orally active selective CDK4 and CDK6 inhibitor Palbociclib (PD 0332991).
T63634 Palbociclib dihydrochloride
Palbociclib (PD 0332991) dihydrochloride is an orally active, selective inhibitor of CDK4 (IC50: 11 nM) and CDK6 (IC50: 16 nM). Palbociclib dihydrochloride has anti-proliferative activity and cell cycle arrest in HR-posi...
T33865 Palbociclib-SMCC PD0332991-SMCC,Palbociclib-SMCC linker,PD 0332991-SMCC,PD-0332991-SMCC
Palbociclib-SMCC is a Palbociclib derivative with a SMCC linker.
T63576 Palbociclib hydrochloride
Palbociclib (PD 0332991) hydrochloride is a selective and potent inhibitor of CDK4 (IC50: 11 nM) and CDK6 (IC50: 16 nM). Palbociclib hydrochloride has anti-proliferative effects on cancer cells and induces cell cycle arr...
T12355 Palbociclib-d8 PD 0332991 D8,Palbociclib D8 CDK
Palbociclib D8 is a deuterium labeled Palbociclib. Palbociclib is a selective and orally active inhibitor of CDK4 and CDK6 (IC50s of 11 and 16 nM, respectively).
T64486 6-Desacetyl Palbociclib
6-Desacetyl Palbociclib is a useful organic compound for research related to life sciences and the catalog number is T64486.
T72507 Palbociclib orotate PD 0332991 orotate CDK
Palbociclib (PD 0332991) orotate, an orally active selective inhibitor of CDK4 and CDK6, exhibits IC50 values of 11 and 16 nM, respectively. This compound demonstrates potent anti-proliferative effects and induces cell c...
T28291 Palbociclib-Succinic acid Palbociclib-hemi Succinic acid,Palbociclib-Succinate,
Palbociclib-Succinic acid is a Palbociclib- derivative with a succinic acid linker. The carboxy group of Palbociclib-Succinic acid can be used to conjugate with other molecules such as peptides, proteins, or polymers. Pa...
Cat No. Product Name Synonyms Targets
T82055 Ipalbidine
Ipalbidine, an alkaloid derived from Ipomoea hardwickii Hemsl., exhibits dose-dependent analgesic effects [1].
TN1889 Lupalbigenin ERK , Akt , Topoisomerase
Lupalbigenin sensitizes detachment-induced cell death in human lung cancer cell through down-regulation of pro-survival proteins.
T12353 Palbinone Others
Palbinone is a terpenoid isolated from the roots of Paeonia albiflora Pallas, with anti-inflammatory activity.
T82054 Ipalbine
Ipalbine is an alkaloid of the hexahydroindolizine class, extractable from the plant Ipomoea alba L. [1].
TN4308 Isolupalbigenin Antifection
Isolupalbigenin shows promising cytotoxic effects toward HL-60 cells (IC50 4.3 ± 0.7 to 18.0 ± 1.7 uM), it also shows in vitro inhibitory activity toward human glyoxalase I. Isolupalbigenin shows two different antibacter...

Natural Products

Ipalbidine
T82055
Synonym:
Target:
Lupalbigenin
TN1889
Synonym:
Target: ERK, Akt, Topoisomerase
Palbinone
T12353
Synonym:
Target: Others
Ipalbine
T82054
Synonym:
Target:
Isolupalbigenin
TN4308
Synonym:
Target: Antifection

Recombinant Proteins

Species：
Human (2)
Cynomolgus (1)
Expression System：
HEK293 Cells (3)
Tag：
C-His (1)
His (1)
N-His (1)
Cat No. Product Name Species Expression System
TMPY-01756 Transthyretin Protein, Human, Recombinant (His) Human HEK293 Cells
Transthyretin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is E9KL36.
TMPK-01090 Transthyretin/Prealbumin Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
Transthyretin is a highly conserved homotetrameric protein, mainly synthetized by the liver and the choroid plexus of brain. The carrier role of TTR is well-known; however, many other functions have emerged, namely in th...
TMPY-00261 Meprin beta Protein, Human, Recombinant (His) Human HEK293 Cells
MEP1B (Meprin A Subunit Beta) is a Protein Coding gene. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the me...
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